Vessels, Heart Structure And Function, Cardiac Cycle, Heart Disease Flashcards

(47 cards)

1
Q

Why do large organisms, like mammals, require a circulatory or transport system?

A

Larger organisms have smaller surface area to volume ratios, so a transport system is needed to supply oxygen and glucose to every metabolically active cell in their large volume.

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2
Q

What does ‘Double Circulatory System’ mean?

A

It means that the blood passes through the heart twice for each complete circuit of the body, once in the pulmonary circuit to the lungs and once in the systemic circuit to the rest of the body tissues.

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3
Q

Why does the right ventricle not need to generate much pressure?

A

The pulmonary circuit to the lungs is only a short circuit.

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4
Q

What is the advantage of the low pressure in the pulmonary circuit?

A

There is more time for gas exchange between the alveoli and the capillaries of the lungs.

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5
Q

Why is the wall of the left ventricle much more muscular?

A

The blood in the systemic circuit must be under large enough pressure to deliver glucose and oxygen quickly to our organs and tissues as well as take wastes away quickly.

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6
Q

What is the advantage to mammals of having a 4 chambered heart and double circulation?

A

Oxygenated blood can be delivered quicker and at a greater pressure to all the cells. This allows mammals to be larger and lead active lives with high energy demands.

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7
Q

What is the disadvantage of a single circulatory system, as seen in fish?

A

As there is only a single circuit, once blood has passed through the gill capillaries, its pressure is reduced which means less pressure behind the blood flow to other body organs.

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8
Q

What is the role of the elastic tissue in the thick walls of arteries?

A

Elastic tissue allows arteries to 1. Stretch/distend to withstand the high pressure.
And 2. Recoil between heart beats to maintain pressure and push blood along

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9
Q

What is the role of smooth muscle in the thick walls of arteries?

A

Smooth muscle controls blood flow to organs via vasoconstriction (narrowing of lumen when smooth muscle contracts) and vasodilation (widening of lumen). It helps to maintain blood pressure via vasoconstriction.

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10
Q

What is the role of the inner squamous endothelium layer of both arteries and veins?

A

It provides a smooth surface for reducing friction to blood flow.

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11
Q

What is the role of the thin outer fibrous layer of arteries and veins?

A

Protection.

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12
Q

What is the significance of having less smooth muscle and elastic tissue, a larger lumen and the presence of valves in veins when compared to arteries?

A

The blood is under much lower pressure in veins, therefore less elastic tissue and smooth muscle is needed. The large lumen means that there is little resistance to blood flow. The valves prevent backflow of blood.

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13
Q

What is the only tissue layer that arteries, veins and capillaries have in common?

A

The squamous endothelium.

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14
Q

What happens in the capillaries?

A

The exchange of gases, solutes and wastes between the blood and the tissue fluid surrounding cells and tissues.

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15
Q

How are capillaries adapted for exchange?

A

They have thin permeable walls to reduce diffusion distance, a narrow lumen which reduces diffusion distance and allows RBCs to squeeze through slowly, and huge networks of capillaries that increase surface area for diffusion.

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16
Q

Why does both blood pressure and velocity drop when blood reaches the capillaries?

A

The arterioles branch into millions of capillaries in huge capillary networks which causes a large increase in surface area.

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17
Q

How is the heart muscle ‘myogenic’?

A

Myogenic means that it can generate its own electrical impulses to cause contraction.

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18
Q

How is the heart supplied with the oxygen and glucose it needs to maintain its high metabolic rate?

A

The coronary arteries supply the cardiac muscle with oxygen and glucose.

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19
Q

How are cardiac muscle cells adapted to their function?

A

They are branched and have bridges to enable conduction of electrical impulses through walls of atria and ventricles.

20
Q

Why are the atria only thin-walled?

A

They need less cardiac muscle as they only receive blood (from the body or the lungs).

21
Q

Why do the ventricles have thicker walls?

A

They have more cardiac muscle to enable them to generate the pressure needed to pump the blood all around the body (left ventricle) and to the lungs (right ventricle).

22
Q

What is the job of the atrio-ventricular or AV valves (tricuspid and bicuspid)?

A

They prevent backflow into the atria when the ventricles contract.

23
Q

What is the job of the semilunar or pocket valves? (pulmonary and aortic)?

A

They prevent backflow from the pulmonary artery and the aorta into the ventricles during diastole.

24
Q

Why do the AV valves have chordae tendinae attaching them onto papillary muscles on the ventricle walls?

A

The chordae tendinae are tough, flexible structures needed to prevent the AV valves from turning inside out during ventricular contraction.

25
The semilunar valves are pocket valves. What does this mean?
They close when the pressure in the arteries leaving the heart is greater than in the ventricles but are pushed flat against the artery walls during systole so they don't impede flow out of the heart.
26
What are the valves made from?
Connective tissue.
27
What is the cardiac cycle?
The sequence of events that occur during one heart-beat.
28
In the cardiac cycle, what causes the AV valves to open initially?
The refilling of the atria during diastole increases the pressure in the atria to above that in the ventricles.
29
What causes the AV valves to then shut?
Ventricular systole begins which increases the pressure in the ventricles to above the pressure in the atria.
30
What causes the semi-lunar valves (pulmonary and aortic) to open?
During ventricular systole, when the pressure in the ventricles becomes greater than in the arteries, the semi-lunar valves are forced open.
31
What causes the semi-lunar valves (pulmonary and aortic) to slam shut?
The blood has left the ventricles and entered the arteries and ventricle walls relax making the pressure in the arteries greater than the pressure in the ventricles.
32
What causes the 2 heart sounds?
1. The AV valves shutting 2. The semi-lunar valves shutting.
33
Where does the electrical signal which causes the atria to contract originate?
The sino-atrial node or SAN, found in the wall of the right atrium.
34
Where does the electrical signal that causes the ventricles to contract originate from?
The atrio-ventricular node or AVN, found in the right atrium, closer to the AV valves.
35
How does the electrical signal from the AVN reach the ventricular walls?
The impulse travels down the septum, in the BUNDLE OF HIS to the apex of the heart and then up the ventricle walls in PURKINJE FIBRES.
36
Why is it important that ventricular systole is initiated from the bottom of the chambers (apex of heart) upwards?
This ensures that blood is pumped upwards and into the arteries leaving the heart.
37
What is an electrocardiogram (ECG)?
An ECG is a graphical representation of the electrical activity in the heart during the cardiac cycle.
38
What is atherosclerosis?
Atherosclerosis is the disease caused by thickening of the artery wall which reduces the size of the lumen and increases the blood pressure.
39
What is an atheroma?
An atheroma is a build-up of fatty deposits that form within an artery wall.
40
How does the atheroma grow and form a hardened plaque?
Within the artery wall, macrophages, cholesterol, dead smooth muscle cells, salts and fibrous tissue build up to form a hardened plaque.
41
How do atheromas and hardened plaques affect structure and function of the artery?
1. The atheromas/plaques narrow the lumen, which restricts blood flow and raises blood pressure. 2. The build-up of fibrous material reduces elasticity, reducing the ability to carry out vasoconstriction and vasodilation.
42
What is a thrombosis?
Thrombosis is the formation of blood clots within the blood vessels.
43
What is a coronary thrombosis?
Coronary thrombosis occurs when the blood clots are found in the coronary arteries.
44
What might cause the coronary thrombosis?
Damage caused by atherosclerosis and plaques rupturing.
45
What is an angiogram?
An angiogram is a special x-ray image produced which shows the journey of a contrast dye through the blood vessels.
46
What is an angiogram used for?
It shows up narrowing or damage to blood vessels.
47
What treatment may be used to treat narrowing of a coronary blood vessel?
Angioplasty, which uses a stent to dilate the relevant area.