VIII - Mycology

Question 1

Single celled, budding form of fungi

Answer 1

Yeast

Question 2

Hyphaeted, mitotic form of fungi

Answer 2

Molds

Question 3

Fungal form at room temp

Answer 3

Molds

Question 4

Fungal form at body temp

Answer 4

Yeast

Question 5

Amanita mushroom toxin, causing liver necrosis

Answer 5

Amanitin, phyllodin

Question 6

Aspergillus flavus toxin, causing liver CA

Answer 6

Aflatoxin

Question 7

Aspergillus spp causing bronchopulmonary aspergillosis

Answer 7

Aspergillus fumigatus

Question 8

Fungi agar

Answer 8

Sabouraud agar

Question 9

Antifungal, squalene oxidase inhibitor

Answer 9

Terbinafine

Question 10

Antifungal, disrupts microtubule function

Answer 10

Griseofulvin

Question 11

Antifungal, inhibits glucan synthase

Answer 11

Echonocandins

Question 12

Antifungal, disrupts ergosterol synthesis

Answer 12

Azoles

Question 13

Antifungal, binds to ergosterol, forms pores

Answer 13

Amphotericin

Question 14

3 important dermatophytoses

Answer 14

Microsporum canis, Trichophyton tonsuras, Epidermophyton floccosum

Question 15

Enzyme of dermatophytes, allows infection of superficial keratinized structures

Answer 15

Keratinase

Question 16

green fluorescence on Wood’s lamp

Answer 16

Dermatophytoses (tinea)

Question 17

Tinea versicolor

Answer 17

Malassezia furfur

Question 18

Spaghetti and meatball findings on microscopy

Answer 18

Malassezia furfur

Question 19

DOC for tinea versicolor

Answer 19

Miconazole

Question 20

Etiology of Valley fever (desert bump, lung inflitrates, meningitis)

Answer 20

Coccidioides immitis

Question 21

Coccidioides in soil, form

Answer 21

Molds

Question 22

Coccidioides in tissue, form

Answer 22

Spherules

Question 23

Transmission of Coccidoides

Answer 23

Arthrospores

Question 24

DOC in Coccidioides

Answer 24

Amphotericin B

Question 25

Mycosis, mimics pTB

Answer 25

Histoplasmosis

Question 26

2 forms of Histoplasma

Answer 26

macroconidia, microconidia

Question 27

Transmissible form of Histoplasma

Answer 27

Microconidia

Question 28

Found in bird droppings and bat guano

Answer 28

Histoplasma microronidia

Question 29

Microscopic findings in Histoplasma

Answer 29

Budding yeast in macrophages

Question 30

DOC in Histoplasma

Answer 30

Amphotericin

Question 31

Round yeast with broad based bud

Answer 31

Blastomyces dermatitidis

Question 32

MCC of fungal pneumonia

Answer 32

Blastomyces dermatitidis

Question 33

DOC in Blastomycosis

Answer 33

Itraconazole

Question 34

Mariner's wheel morphology, fungi

Answer 34

Paracoccidioides brasiliensis

Question 35

DOC in Paracoccidioides

Answer 35

Itraconazole

Question 36

2 forms of Candida albicans

Answer 36

Germ tubes (blood), chlamydospores (culture)

Question 37

Pseudomembranous esophagitis

Answer 37

Candid albicans

Question 38

DOC oral candidiasis

Answer 38

Nystatin swish and swallow

Question 39

DOC systemic candidiasis

Answer 39

Amphotericin B

Question 40

Oval yeast, narrow based buds, thick capsule

Answer 40

Cryptococcus neoformans

Question 41

Transmission of Cryptococcus

Answer 41

Yeast in pigeon droppings

Question 42

MCC of meningitis in HIV

Answer 42

Cryptococcus neoformans

Question 43

DOC in cryptococcosis

Answer 43

Amphotericin B

Question 44

Exist only as molds

Answer 44

Aspergillus fumigatus

Question 45

Septate hyphae are V-shaped, acute angles

Answer 45

Aspergillus fumigatus

Question 46

Presents with fungus ball in lung cavities and allergic bronchopulmonary aspergillosis

Answer 46

Aspergillus fumigatus

Question 47

DOC in Aspergillosis

Answer 47

Amphotericin B

Question 48

Nonseptate hyphae, right angles

Answer 48

Mucormycosis, Rhizopus oryzae

Question 49

MC AIDS-defining illness

Answer 49

Pneumocystis carinii pneumonia

Question 50

CD4 count for PCP

Answer 50

CD4 <200