Vinca Alkaloids. Flashcards
1
Q
What is the MOA of vinca alkaloids?
A
They prevent the assembly of
microtubules.
2
Q
What are the 3 vinca alkaloids?
A
VinBLAStine.
VinCRIStine.
VinORELBine.
3
Q
What is vinblastine used to treat?
A
Mast cell tumours.
4
Q
What drug can be used as a replacement for vincristine in
lymphoma protocols?
A
Vinblastine.
5
Q
What is vincristine used to treat?
A
Lymphomas.
6
Q
What are the unique side effects of vincristine?
A
It increases peripheral platelet count.
It is the most likely of the vincas to cause neurotoxicity.
7
Q
What is vinorelbine used to treat?
A
Pulmonary
carcinomas.
