vinca alkaloids Flashcards
(6 cards)
1
Q
used in what regiments
A
in various cancer chemotherapy regiments
2
Q
what route
A
intravenously
3
Q
in combo with what
A
Often in combination with intrathecal methotrexate
4
Q
why do we need 2 know this
A
Administration of intravenous vinca alkaloids via the intrathecal route is almost always fatal
5
Q
therefore as a result
A
In the UK and many other countries, guidance and protocols have been issued that specify the exact processes required for the administration of intravenous vincristine (and other vinca alkaloids) in patients also receiving intrathecal chemotherapy
6
Q
UK intrathecal guidance Includes: (5)
A
- Designated centres
- Local register
- Intrathecal (IT) medication prescribed on separate prescription / audit trail
- IT and IV chemotherapy separated in TIME and LOCATION, and in appearance
- Administration checks