Viral Causes of Skin Disease Flashcards

1
Q

Importance of viral skin disease

A

More common in large animal practice
Many LA viral skin diseases are NOTIFIABLE

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2
Q

Why are viral skin diseases notifiable?

A

Serious economic losses associate with infections
Some also zoonotic

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3
Q

Notifiable viral skin diseases

A

○ Foot and Mouth Disease
○ Vesicular Stomatitis
○ Swine Vesicular Disease
○ Bluetongue Virus
○ Rinderpest
○ Lumpy skin disease
○ Scrapie
○ Classical Swine Fever
○ African Swine fever
○ Sheep Pox
○ Goat Pox

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4
Q

What must you do if you diagnose a notifiable disease?

A

Legal obligation to report to APHA
Usually no treatment
Slaughter and disposal or infected/in-contact animals
Quarantine/protection zones
Movement restrictions
+/- vaccination
Eradication programmes
Surveillance programmes

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5
Q

Types of viral skin infections

A

Vesicular diseases
Papillomaviruses
Poxviruses
Parapoxviruses
Post-weaning Multisystemic Wasting Disease (PMWD)
Circovirus
Border disease - pestivirus

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6
Q

Vesicular disease clinical signs

A

Vesicles -> erosions/ulcers -> crusts
Locations:
○ Muzzle
○ Oral mucosa
○ Tongue
○ Udder/teats
○ Coronary band
Can cause shedding of hooves and horns

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7
Q

What species do vesicular diseases affect?

A

Wide range
Cloven foot species

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8
Q

Importance of vesicular disease

A

Many are notifable
Often difficult to differentiate from non-notifiable vesicular disease
Wide economic loss
Some are zoonotic

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9
Q

Non-notifiable vesicular diseases

A

○ Mucosae disease
○ Malignant catarrhal fever
○ Infectious Bovine Rhinotracheitis
○ Bovine herpes mammillitis

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10
Q

Notifiable vesicular diseases

A

○ Foot and Mouth Disease
○ Vesicular Stomatitis
○ Swine Vesicular Disease
○ Bluetongue Virus
○ Rinderpest

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11
Q

Characteristics of papillomaviruses

A

Epitheliotropic
* Proliferative lesions
* Papillomas
Host specific
Enter via microabrasions
Usually occur in young animals
Regress spontaneously
Rarely undergo malignant transformation to SSC

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12
Q

Papillomavirus in cattle

A

Bovine Papilloma Virus (BPV)
* Very common
* Transmitted by fence posts, halters, tagging equipment

Can induce sarcomas/fibrosarcomas

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13
Q

Papillomaviruses in horses

A

BPV can cause equine sarcoids
* Transmitted by flies or tack

Equine papillomavirus
* ‘grass warts’ in young horses
Self limiting
* Aural plaques in pinna in older horses
Persist

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14
Q

Papillomaviruses in dogs

A

Canine Papilloma virus
○ Warts
Young dogs
Self-limiting
○ Pigmeneted viral plaques
French bulldogs
Lesions may persist

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15
Q

Pox virus characteristics

A

Macules - colour change
Papules
Vesicles
Pustules
Crusts

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16
Q

Examples of pox diseases

A

Cowpox
Horsepox - rare
Swinepox - mild
Sheep pox
Lumpy skin disease (capripox virus)
Myxomatosis

17
Q

Cowpox

A

Rare in cattle
Causes disease in cats
Infected by rodent bite
Zoonotic

18
Q

Sheep pox

A

Notifiable
Not in UK

19
Q

Lumpy skin disease

A

In cattle
Notifiable
Rare but reported

20
Q

Myxmatosis

A

Common disease of rabbits
Transmitted by fleas
Oedematous thickened eyelids, lips, genitalia

21
Q

Parapoxviruses examples

A

Similar to pox viruses
* Contagious pustular dermatitis (orf)
* Pseudocowpox
* Bovine papular stomatitis

22
Q

Contagious pustular dermatitis (orf)

A

Common disease in sheep
* Oral lesions on lambs
* Teat lesions on ewes (mastitis)

Economic and welfare importance

23
Q

Pseudocowpox

A

Common teat disease in cattle

24
Q

Bovine papular stomatitis

A

Mild disease
Oral/muzle lesions
Differential diagnosis for FMD

25
Q

Post-weaning Multisystemic Wasting Disease (PMWD)/ Porcine Dermatitis Nephropathy Syndrome (PDNS)

A

Ubiquitous circovirus infection
May have blotchy purpuric skin lesions
Differential diagnosis for classic/african swine fever

26
Q

Border disease

A

Pestivirus in sheep
Congential infections
Small weak hairy lambs with skeletal muscle tremors
Causes abortion/still birth

27
Q

Diagnosis for viral skin disease

A

Virus isolation
PCR/RT-PCR
Histopathology
Immune-fluoresce
Haemagglutination
ELISA
Serum Neutralisation
Complement fixation

28
Q

Protozoal skin disease

A

Leishmaniasis - caused by leishmania spp.
* Transmitted by blood sucking sandflies
* Not currently endemic in UK
○ Seen in imported dogs
* Causes wide range of skin and systemic signs
○ Long incubation
○ Slowly progressive
* Can control but not cure