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Z Dermatology Clin Med > Viral Disorders of skin > Flashcards

Viral Disorders of skin Flashcards

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1
Q

Other names for Erythema Infectiosum?

A

-5ths disease -Slapped-cheek disease

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2
Q

Viral cause of Erythema Infectiosum?

A

Parvovirus B19

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3
Q

Predisposing conditions for Erythema infectiosum?

A

-Exposure -Late winter/early spring -Community outbreak

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4
Q

Treatment for Erythema infectiosum?

A

Supportive (NOT contagious once rash appears)

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5
Q

How long does Erythema infectiosum usually last?

A

A few days to several weeks

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6
Q

Clinical features of Erythema infectiosum? (In order of appearance)

A

-Incubation period of 4-14 days -Prodrome -burning, hot “slapped-cheek” -generalized reticular rash -may be asymptomatic

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7
Q

Complications with Erythema infectiosum?

A

-Recurrance (triggers: sun, exercise, bathing, stress) -Miscarriage -Hydrops fatalis in pregnancy

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8
Q

Definition of Hand, Foot, & Mouth Disease?

A

short-lived, contagious viral infection

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9
Q

Viral cause of Hand, Foot, & Mouth Disease?

A

-Coxsackie A 16 Virus -Enterovirus 71

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10
Q

Predisposing conditions of Hand, Foot, & Mouth Disease?

A

-Late summer/early fall -Children <5 -Household Contacts

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11
Q

Clinical features of Hand, Foot, & Mouth Disease? (in order of appearance)

A

-4-6 day incubation period -small vesicles form in mouth -square, yellow vesicles appear on hands, feet, and buttocks -vesicles –> bullae –> erosions

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12
Q

How long does Hand, Foot, & Mouth disease usually last?

A

7-10 days without complications

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13
Q

Treatment for Hand, Foot, & Mouth disease?

A

Symptomatic

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14
Q

Complications with Hand, Foot, & Mouth disease?

A

-Rare -Miscarriage -Fetal growth retardation

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15
Q

Definition of Herpes Simplex Virus?

A

Acute viral infection involving skin and mucous membranes

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16
Q

Viral cause of Herpes Simplex?

A

Herpes Simplex Virus 1 & 2

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17
Q

Predisposing conditions for Herpes Simplex?

A

-Direct contact -Droplet infection -Open skin

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18
Q

Clinical features for primary infection of Herpes simplex?

A

-Acute development of grouped macules –> painful vesicles –> eroding to crusts -possible prodrome -lymphadenopathy -lies dormant in dorsal root ganglia -many are asymptomatic

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19
Q

Clinical features for secondary infection of Herpes simplex?

A

-Reactivation of virus -Travels thru peripheral nerves -Predisposed via menses, fatigue, stress, trauma, sunlight -Fewer vesicles; localized -Rarely associated w/ constitutional symptoms

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20
Q

Where is Herpes simplex - primary infection - mostly manifested?

A

Facial/oral

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21
Q

Where is Herpes simplex - secondary infection - mostly manifested?

A

Genitalia

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22
Q

Treatment for Herpes simplex?

A

-Symptomatic -Topical/PO antivirals

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23
Q

Complications with Herpes simplex?

A

-Disseminated herpes simplex -herpetic whitlow -erythema multiforme

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24
Q

How to diagnose Herpes simplex?

A

-Clinical presentation -PCR -Tzanck smear -Serum assay

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25
Definition of Varicella?
highly contagious viral infection resulting in lifelong immunity
26
Viral cause of Varicella?
Varicella zoster virus (Herpes virus 3)
27
Predisposing conditions to Varicella?
- Exposure - Immunosuppression
28
Clinical features of Varicella?
- 10-23 day incubation period - HIGH contagiousness level - Prodrome for 1-2 days - Crops of pruritic macules --\> teardrop vesicles --\> crust over w/in 6-8 hours - Surrounding erythema
29
Treatment for Varicella?
- symptomatic in uncomplicated cases - antiviral agents if indicated
30
Distinguishing phrase for Varicella?
'Dew drop on a rose petal'
31
Complications of Varicella?
- Hemorrhagic varicella - Secondary infection - Encephalitis - Pneumonia - Myocarditis - Hepatitis - Can spread in utero during pregancy - 30% mortality to newborns
32
Definition of Herpes Zoster (Shingles)?
acute, unilateral, localized infection usually involving a single dermatome
33
Viral cause of Herpes zoster?
Reactivation of varicella zoster virus
34
Predisposing conditions for Herpes Zoster?
- Immunosuppression - Localized trauma - increased age (\>70) - lymphoma/malignancy - radiation/chemotherapy - steroids - stress
35
Clinical features of Herpes Zoster?
- 3-5 days of localized symptoms (PAINFUL) - Red macule --\> papular --\> vesicular - Surrounded by erythema - Vesicles group over 2-3 weeks, become pustular, scab over - Scabs fall off, leave white scar - Fever, chills, etc. may precede eruption
36
Treatment for Herpes Zoster?
- PO Antiviral - Gabapentin (nerve pain modulator) - rest - topical analgesics - steroids - sympathetic blocks
37
Complications with Herpes Zoster?
- post-herpetic neuralgia - disseminated herpes zoster - Ramsey-Hunt's syndrome - Herpes zoster ophthalmicus (can lead to blindness) - Bell's palsy - cerebellitis
38
Prevention for Herpes Zoster?
Vaccine (must be \>60 years)
39
Prevention for Varicella?
Childhood immunization (\>12 mo.)
40
Definition of Molluscum Contagiosum?
self-limiting mucocutaneous viral infection
41
Viral cause of Molluscum Contagiosum?
Poxvirus
42
Predisposing conditions to Molluscum Contagiosum?
- Swimming pools - children - communal bathing - atopic dermatitis - close contact - autoinoculation
43
Clinical features of Molluscum Contagiosum?
- Asymptomatic skin-colored papule - dome-shaped w/ central punctum
44
Treatment for Molluscum Contagiosum?
- Supportive - topical tretinoin - Aldara (immune modulator) - Cantharidin (erodes area) - liquid N2 - surgical/destructive tx
45
Complications of Molluscum Contagiosum?
Rare, but occasional scarring
46
Definition of Measles (Rubeola)?
highly contagious childhood viral infection; spreads from neck down
47
Viral cause of Measles?
Paramyxovirus group
48
Predisposing conditions of Measles?
- densely populated/socioeconomically depressed areas - winter/spring
49
Clinical features of Measles?
- 10-15 day incubation period - Prodrome of **3 C's** - cough, coryza, conjunctivitis - "Koplik spots" - blue/white on buccal mucosa during prodrome - red macules/papules on 4th day - face/neck/ears - become papules, spread to trunk & limbs w/in 3-4 days - lesions coalesce, clear in 3 days - leaves brown stain behind
50
Treatment for Measles?
- Symptomatic - Antibiotics if secondary infection develops
51
Complications for Measles?
- secondary bacterial infection - post-infectious encephalitis - myocarditis - viral pneumonitis - OM - GI problems - glomerulonephritis
52
Prevention of Measles?
Live-attenuated vaccine
53
Definition of Rubella?
common viral infection affecting skin, lymph nodes, and joints
54
Viral cause of Rubella?
Togavirus
55
Predisposing conditions for Rubella?
- alck of proper immunizations - springtime
56
Clinical features of Rubella?
- Incubation period 14-21 days - Prodrome follows - Small, pink macules coincide with prodrome - begins on face/scalp, spreads down - Macules become papular, then desquamate - Papules fade w/in 3 days - Red petechiae may occur on soft palate
57
Treatment for Rubella?
Symptomatic
58
Complications of Rubella?
Threat to unborn child
59
Prevention of Rubella?
MMR vaccination
60
Other terms for Rubella?
- German measles - "3 Day Measles"
61
Other terms for Roseola Infantum?
- Childhood exanthem - Exanthem subitum - 6th Disease
62
Viral cause of Roseola Infantum?
-Human Herpes Virus (HHV) 6 or 7
63
Predisposing conditions to Roseola Infantum?
- exposure - 6-24 month-olds, otherwise healthy
64
Clinical features of Roseola Infantum?
- incubation of 5-15 days - high fever each night, no day fever - followed by pink maculopapular rash 3-4 days later - usually trunk & neck - otherwise asymptomatic - febrile seizures common
65
Treatment of Roseola Infantum?
Symptomatic
66
Definition of Warts?
Common viral infections of skin and mucous membranes
67
Viral cause of warts?
Human papilloma virus (HPV)
68
Predisposing conditions of warts?
- Localized trauma - immunosuppression - communal bathing
69
4 different types of warts?
- Common - Plane (flat) - Plantar - Mosaic
70
Characteristics of Common Wart?
- Skin-colored/pink - Thrombosed capillaries (patches of black streaks) - Papules, smooth --\> rough - Hands, anywhere
71
Characteristics of Plane (Flat) warts?
- Skin-colored, pink - Smooth plaque surface (shiny) - Face, hands, limbs
72
Characteristics of Plantar warts?
- Skin-colored - thrombosed capillaries - raised, rough, thick - feet - can be painful
73
Characteristics of Mosaic warts?
- skin-colored - thrombosed capillaries - rough plaque - soles, heels, palmar, periungual (skinfolds underneath nails)
74
Treatment of warts?
- spontaneous involution - physical (N2, duct tape) - chemical - immunotherapy - phototherapy - chemotherapy
75
Complications of warts?
- recurrence - spread to contacts/self-innoculation - extension to tx periphery
76
Prevention of warts?
- keep surfaces clean/dry - aqua socks/flip flops/slippers in common areas

Z Dermatology Clin Med (18 decks)

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