Viral Etiology of tumors Flashcards

(38 cards)

1
Q

Cervical cancer is linked to what virus

A

HPV

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2
Q

HTLV 1 infects what lymphocytes

A

CD4+ T lymphocytes

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3
Q

HTLV 1 retrovirus can be transmitted through

A

Blood transfer
Breast milk

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4
Q

HTLV 1 appears to drive cell growth through the expression of ………….. in latently infected cells

A

Tax

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5
Q

EBV is found in what cancers

A

Burkitt’s lymphoma
Nasopharyngeal carcinoma

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6
Q

Which cancer can be found in patients with AIDS

A

Kaposi’s sarcoma

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7
Q

Kaposi tumors generally appear on

A

Upper body
Oral areas

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8
Q

What virus causes hepatitis in humans

A

HBV

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9
Q

List the genes of the HBV genome

A

Pol
Env
Pre-core
X

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10
Q

List the main risk factors for the development of Hepatocellular carcinoma

A

HBV
HCV
Alcoholism
Aflatoxin intake

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11
Q

Viral families associated with Viral Hemorrhagic fever

A

Arenaviridae
Filoviridae
Flaviviridae
Bunyaviridae
Togaviridae

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12
Q

Arenaviridae transmission and human infection

A

•Transmitted through rodents
•Human infection-Excreta contact, contaminated materials, aerosols

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13
Q

Incubation period of Arenaviridae

A

2-21days

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14
Q

When do Fever and malaise occur in arenaviridae infection

A

2-6days

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15
Q

The hemorrhagic stage of Arenaviridae includes

A

Hemorrhage, Leukopenia, Thrombocytopenia

Neurological signs

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16
Q

Bunyaviridae transmission

A

Arthropods (except Hantavirus)

17
Q

RVF is transmitted by

A

Aedes mosquito

18
Q

CCHF is transmitted by

19
Q

Hantavirus is transmitted by

20
Q

Incubation period of RVF

21
Q

Incubation of CCHF

22
Q

Incubation period of Hantavirus

23
Q

Rate of abortion in animals afflicted with viruses from Bunyaviridae

24
Q

Reservoir of Filoviridae transmission

25
Filoviridae transmission
•Intimate contact •Nosocomial transmission •Aerosol transmission
26
The most severe hemorrhagic fever
Filoviridae in Humans
27
Incubation period of Filoviridae
2-21 days
28
Death due to filoviridae in humans could result in what day
7-11
29
What virus of filoviridae causes Ebola in non human primates
Ebola Reston Mortality-82%
30
Transmission of yellow fever and dengue viruses
Aedes aegypti •Sylvatic(jungle) cycle •Urban(epidemic) cycle
31
Transmission of Kasanur forest virus
Ixodid tick
32
Transmission of Omsk Hemorrhagic Fever virus
Muskrat urine, faeces, blood
33
Incubation period of Yellow fever
3-6days
34
Incubation period of Dengue Hemorrhagic Fever
2-5 days
35
Ribavirin treatment of VHF
Arenaviridae and Bunyaviridae only Effective in some individuals Not approved by FDA
36
Convalescent phase plasma is used in the treatment of
Argentine HF Bolivian HF Ebola
37
The most stable VHF in liquid or frozen states
Rift Valley fever
38
VHFs pose a threat as aerosolized agents T/F
T