VIRAL GI - ROTAVIRUS Flashcards
(6 cards)
1
Q
who does rotavirus infect most
A
young children
2
Q
Appearance of rota virus
A
Naked virus - no envelope
spherical in appearance
3
Q
what does rotavirus cause
A
Infant accosiated gastroenteritis - faecal oral transmission
4
Q
is there a vaccination for rotavirus?
A
yes there is a vaccination but the symptoms are usually self limiting when you take electrolytes and fluid replacement
5
Q
how does rotavirus enter and infect
A
it infects mature enterocytes
virus enters via an endosome
the endosome then releases the viral particle into the cytoplasm
the lipid droplets help form viroplasm where new viral particles are produced
exists via cell lysis
6
Q
symptoms of rotavirus
A
watery stools - diarrhoea
abdominal cramps
