Viral Hep Flashcards
(22 cards)
Risk of chronic hep in hep b
1 to 90%
What is 90% in hep b
Is HbeAg +
Chr hep in hep c
85%
Chr hep in hep A and E
0% coz its fecooral
Mc acute hep
Hep e
Hep e in preg
20% risk of mortality
Mx of hep b
If hbv dna >2000iu/ml
Tenofovir+ entecavir for 12 wks
Plus interferon alpha
Hep c tx
Previously: inf alpha ribavirin
Protease inh: previr( telaprevir)
NS5A replication inh: asvir(velpatasvir)
NS5B inh: osbu( sofosbuvir)
First line for hep c
Velpatasvir + sofasbuvir 12 wks
First antigen to rise
HBsag
Acute phase
Anti Hbc igM
Chronic phase
Anti Hbc igG
Recovery
Hbs antibody/ anti Hbs
Anti HBs can also mean
Vaccine
In window period
Only anti hbc
If HBe Ag raised
High infective
Anti HBe
Low infective
HBs ag + igG anti HBe +
Inactive carrier
HBsAg + igG anti HBe + alt raised and hbv dna > 2000
Precore mutant
Acute hep b + anti HDV +
Acute hep b and d co inf
Chronic hep b + anti HDV +
Super inf chronic hep b + d inf
Anti HBc igM+ HBeAg +
Window period