Viral infections Flashcards
(18 cards)
Varicella causative agent
Varicella zoster virus
Lesions in varicella
Vesicle over the red base(dew drop on rose petal appearance)
Pleomorphic rash
Shingles
Acute, cutaneous, segmental eruption
Clinical features of shingles
Pre eruptive:
Fever
Malaise
Excruciation dermatomal burning pain
Eruptive phase:
Unilateral
Dermatomal
Painful grouped vesicles on red base
Complication of shingles and treatment of it
Post eruptive neuralgia
Amitriptaline
Pregabalin
Gabapentin
Treatment of varicella and Herpes zoster
Acyclovir 800 mg 5 times/day * 7 days
Valacyclovir 1g 3 times/day * 7 days
Variants of shingles
Herpes zoster ophthalmicus
Herpes zoster oticus/Ramsay hunt syndrome
Nerves involved in Herpes zoster ophthalmicus and Herpes zoster oticus
Trigeminal nerve frontal branch
Geniculate ganglion - Facial nerve
Triad of Herpes zoster oticus
Facial nerve LMN palsy
Otalgia
Vesicles in EAC
Infectious mononucleosis:
causative organism, clinical features, malignancies
Epstein barr virus
Fever, Pharyngitis, Posterior cervical lymphadenopathy
Drug reaction: Ampicillin induced maculopapular rash
Burkitt’s lymphoma
Hodgkins lymphoma
Nasopharyngeal carcinoma
Oral hairy leukoplakia: Seen in HIV infected patients
Molluscum Contagiousum:
Causative organisms
Benign, self limiting viral infection of keratinocytes
MCV -1 - in children, affects the face
MCV 2- adults, Anogenital region
Sites of Molluscum contagiosum
Face, neck, trunk, perigenitals
Transmission of Molluscum contagiosum
contact, fomites, sexual
Molluscum contagiosum : Clinical features
Incubation period - 2 weeks - 6 months
- Children : pearly white papules
Centrally umbilicated
size : 2-5 mm - Pseudokobeners phenomenon
- Anogenital region in sexually active adults
- Immunocompromised induviduals:
Giant, atypical, extensive, recalcitrant lesions
HIV patients with molluscum contagiosum like lesions
Skin only : Disseminated molluscum
Skin + lungs : Disseminated histoplasmosis
Skin + CNS(meningitis) : Disseminated cryptococcus
Complications of MC
Secondary infections
Conjunctivitis
Superficial punctate keratitis
Investigations of MC
Histopathology :
1. Cup shaped invagination of epidermis into dermis
2. Handerson Patterson bodies: Eosinophilic intracytoplasmic inclusion bodies
Treatment of MC
Expression / Curettage
Chemical cautery, Electrodissection, Cryotherapy
Topical : Imiquimod, KOH, Phenol, Catharidine, Cidofovir
Systemic : Levimasole, Cimetidine
