Viral Infections of Skin

Question 1

What causes Chickenpox?

Answer 1

Varicella zoster or HHV-3

Question 2

What are the two main infections of varicella?

Answer 2

Chickenpox (primary)
Shingles herpes zoster (recurrent)

Question 3

What are the main symtpoms of chickenpox?

Answer 3

fever
headache
malaise
dry cough
sore throat
rash

Question 4

What season does chickenpox like?

Answer 4

winter and early spring

Question 5

Incubation period for chicky?

Answer 5

14-16 days

Question 6

Features of rash of CP?

Answer 6

Macule then papule then vesicle then pustule then crusted papule and finally a scar

Question 7

D/D of rash

Answer 7

Impetigo
Other viral infection
Insect bites
Contact dermatitis

Question 8

Dx of chickenpox?

Answer 8

Clinical
Tzank smear
Immunofluorescence
PCR
Culture
Histopathology

Question 9

Complications of chickenpox?

Answer 9

Gangrene
Thrombocytopenic purpura
Pneumonia
Encephalitis
Arthritis
SJS
Hepatitis

Question 10

Tx of chickenpox?

Answer 10

Children no tx
Adults - oral acyclovir 800 mg 5 times for 7 days
If complicated case then 10 mg/kg/IV every 8 hours for 7 days
Pregnancy - same as adults

Question 11

What is the preexposure prophylaxis for chickenpox?

Answer 11

Varicella live vaccine given 2 doses
if <13 years given with MMR
if >13 years 2 doses 4-8 weeks apart

Question 12

What is the postexposure prophylaxis for chickenpox?

Answer 12

VZIG
Vaccine
Oral Antivirals

Question 13

Herpes zoster is also called?

Answer 13

Shingles

Question 14

Causative agent in HZ?

Answer 14

Reactivation of varicella zoster

Question 15

Characteristics of HZ?

Answer 15

Dermatomal distribution (T1-L2 or CN V1)
Vesicle - pustule (3rd day) - dry crust (7-10 days)

Question 16

Why does reactivation of varicella zoster occur?

Answer 16

Aging
Immunosuppression
Trauma
Surgery
Stress

Question 17

What is post herpetic neuralgia?

Answer 17

Pain after resolution of rash of 1 month

Question 18

Tx of Shingles

Answer 18

Analgesics
Antiviral
in more than 50 years
It also decreases the risk of PHN

Question 19

Prevention of shingles

Answer 19

Zostavax if more than >60 years
It reduces the risk of infection and PHN

Question 20

Complications of Shingles

Answer 20

Cutaneous
Visceral
Neurological

Question 21

Cutaneous complications of Shingles?

Answer 21

Bacterial superinfection
Scarring
Zoster gangrenosum
Cutaneous dissemination

Question 22

Visceral complications of Shingles

Answer 22

Hepatitis
Cystitis
Pneumonia
Arthritis
Esophagitis
Gastritis
Pericarditis

Question 23

Neurological complications of shingles

Answer 23

Post herpetic neuralgia
Deafness
Transverse myelitis
Meningoencephalitis
Nerve palsies
Sensory loss
Ocular complications
Granulomatous angitis causing hemiparesis

Question 24

Herpes simplex virus have two types

Answer 24

HSV-I for oral and facial lesions
HSV-II for genital and rectal lesions

Question 25

HSV-1 lives in?

Answer 25

CN V

Question 26

HSV-2 lives in?

Answer 26

S2-S5

Question 27

Reactivation of HSV can occur due to

Answer 27

fever trauma stress surgery menses

Question 28

Tx of HSV

Answer 28

Self limiting Acyclovir 200mg 5x per day Famicyclovir Valacyclovir

Question 29

What causes warts?

Answer 29

HPV (6 and 11)

Question 30

How do warts spread?

Answer 30

skin to skin shaving

Question 31

Types of warts

Answer 31

Plantar warts Plane warts Filiform warts Common warts

Question 32

What does a wart look like?

Answer 32

brownish papule with rough surfaces cauliflower shaped

Question 33

What is pseudo koebner phenomenon?

Answer 33

IDK

Question 34

Tx of warts

Answer 34

Electrocautery Crytherapy Topical Imiquimod Ablative laser Surgery Podophylin

Question 35

HPV benign or little malignant potential

Answer 35

HPV 6 and 11

Question 36

HPV risk of CA

Answer 36

16, 18, 33 and 35

Question 37

Complications of HPV

Answer 37

C section Recurrent infections Precancerous SCC Fetus can catch it

Question 38

Vaccination of HPV

Answer 38

9 valent HPV (6, 11, 16, 18, 31, 33, 45, 52 and 58) Gardassi 9 (9vHPV)

Question 39

Molluscum contagiosum is caused by?

Answer 39

Pox virus

Question 40

How does molluscum contagiosum spread?

Answer 40

Skin to skin Towels Scratching Shaving STD

Question 41

Features of molluscum contagiousum

Answer 41

Umbilicated waxy shinny looking papule that upon rupture emits cheesy material

Question 42

Tx of molluscum contagiosu,

Answer 42

Self-limiting Cryotherapy Curettage Laser Imiquimod