Virology Flashcards

(34 cards)

1
Q

Which virus doesn’t replicate at body temperature well? Note: so when latent but can’t shed

A

Canine herpes which also results in neonatal death- herpes parties for bitches

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2
Q

Which herpes lead to secondary bacterial infection?

A

Bovine Rhinotrachitis and Feline Rhinotrachitis

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3
Q

Procine herpes [aujeszky disease] is unique because

A

It is the only alpha herpes that goes across species but is not zoonotic

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4
Q

In equine herpes mylencephalitis which tissue is infected by virus

A

The brain and spinal cord, endothelium

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5
Q

No clinical signs in reservoir host and transmission is NOT between susceptible hosts; it has to go through the reservoir
[Hint: infects lymphocytes]

A

Gammaherpes - Carharral Malignant Fever

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6
Q

Which virus is only reproductive and results in mummification before the 70day gestation mark?

A

Porcine parvovirus SMEDI

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7
Q

Which transplacental infection results in abortion and cerebellar hypoplasia?

A

Feline panleukopenia - feline parvovirus

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8
Q

Which dsDNA virus is non-enveloped
herpes, parvo, poxvirus

A

Parvovirus - can survive in the environment/ feces

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9
Q

Which type of pox is zoonotic and epidermal?

A

Leporipox on rabbits and squirrels

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10
Q

Leporipox is different because it affects ___ cells

A

mesenchymal cells and not epithelial cells

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11
Q

With poxvirus what gives life long immunity vs transient immunity

A

Systemic infection gives life long immunity
Local infection gives transient immunity

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12
Q

Which strand + or- can go directly to ribosome?

A

The positive sense strand goes to the ribosome directly to be transcribes but the Negative sense RNA has to make a complementary positive sense strand first

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13
Q

Which virus is associated with old dog encephalitis? [Note: will see keratinized nose and paw]

A

Canine distemper
Old dog encephalitis happens years after recover and leads to neurological deterioration and death
Highly immunogenic with vaccine

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14
Q

Which bovine diseases are associated with paramyxovirus and the bovine respiratory disease complex?

A

Bovine parainfluenza 3 and bovine respiratory synactia virus

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15
Q

What is the rabies flow from peripheral nerves to the brain called?

A

Retrograde axoplasmic flow

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16
Q

Feline panleukopenia/ parvovirus is…
Canine distemper is….
Rabies is…
Vesicular Stomatitis is…

17
Q

Subclinical infection exists in this rhabdovirus and this paramyxovirus

A

Vesicular Stomatitis
Canine distemper

18
Q

BRSV vs BI3 which is immunosuppressive

19
Q

Hemagglutinin

A

Antigen on othromyxovirus for attachment and fusion

20
Q

Neuraminidase

A

Antigen on orthomyxovirus for cleaving viral receptors and increase entry of vision and increased transmission

21
Q

In terms of H/N reassortment, what are pigs?

A

Reassortment host

22
Q

What is unique about the CPE in orthomyxoviruses

A

no inclusion bodies

23
Q

Genetic reservoir for influenza? Generation of new subtypes come from this animal

A

Aquatic birds

24
Q

3 SYSTEMS AFFECTED BY CORONA

A

GI, respiratory, CNS

25
Feline corona virus explained with 2 virus names, mutation in ___ and ____ leading to immune mediated ____
Feline Enteric coronavirus into feline infectious peritonitis Because of spike protein change in monocytes and macrophages Leading to immune mediated vacuities if not cured
26
TGE vs Porcine Epidemic Diarrhea virus
Both cause diarrhea and baby pig mortality TGE is a coronavirus
27
This blunts the intestinal villi of bovines causing diarrhea and less absorption
Betacoronavirus Bovine coronavirus
28
The bovine viral diarrhea virus with non cytopathic strain before 150 days results in...
Shedding and persistent infection
29
Shedding and persistent infection of BVDV can lead to mucosal disease how
with new cytopathic strain added or with a mutation
30
BVDV is from what family
Pestivirus ssRNA vertical or horizontal transmission
31
What changes when the Prpc becomes the Prpsc
It goes from a alpha helical structure to a beta stealth which is strong and resistant to protease so it accumulates in the neurons
32
Why is a prion not immunogenic?
because its a protein not a virus
33
Deer is to Chronic wasting disease as bovine is to
Bovine Spongiform encephalopathy (humans can get this too)
34
Oncogenes retrovirus name 2 and how they differ
Feline Leukemia (FeLV) and Bovine Leukosis (BLV)