Virology

Question 1

Adenovirus

Answer 1

conjunctivitis, pharyngitis

dense basophilic intranuclear inclusion bodies

diarrhea in infant

infectious genome

icosadeltahedral capsid with fibers

poorly chlorinated swimming pools

Question 2

Bunyaviruses

Answer 2

California encephalitis viruses: Celux mosquito, arbovirus, woods, LaCrosse virus, encephalitits, meningitis

Hantoviruses: hemorrhagic, petechiae, ecchymosis, bleeding tissues, rodent feces and urine

Question 3

Coronaviruses

Answer 3

Common cold

SARS

Fecal-oral and respiratory spread

Question 4

HSV

Answer 4

Enveloped, large, DNA, Cowdry type A inclusion bodies, neurotropic, Tzanck smear, multinucleated giant cells, stress-induced recurrence, encephalitis, destruction of temporal lobe, blindness, neonatal HSV

Question 5

CMV

Answer 5

owl’s eye nuclear inclusion body

swollen cells

opportunistic disease

mononucleosis-like syndrome

congenital CMV

intracerebral calcifications microcephaly

Question 6

Epstein-Barr Virus

Answer 6

Mononucleosis, fatigue, pharyngitis, heterophile antibody, atypical lymphocytes, rash, monospot test, ampicillin-induced rash

Question 7

Varicella zoster virus

Answer 7

Crops of vesicular lesions

All stages of lesions at once

Vesicles, latency

multinucleated giant cells

Cowdry type A

nuclear inclusion bodies

Neurotropic

Thymidine kinase

Shingles

Chicken pox

Question 8

Hepatitis A

Answer 8

Fecal-oral spread

Acute, sudden-onset hepatitis

day care center

food-borne

shellfish

picornavirus

Question 9

Hepatitis E

Answer 9

Fecal-oral spread

Acute, sudden-onset hepatitis

Pregnant women

Norovirus

Question 10

Hepatitis B

Answer 10

Serum hepatitis, chronic, Dane particle, insidious onset, HbsAg, hepadnavirus

Question 11

Hepatitis C

Answer 11

Non-A, non-B hepatitis, chronic, flavivirus

Question 12

Hepatitis D

Answer 12

Fulminant hepatitis, HBV helper virus

Question 13

HIV

Answer 13

AIDS CD4 Chemokine coreceptor opportunistic disease: PCP, Kaposi’s sarcoma, C. albicans thrush, CMV retinitis, pneumonitis, reverse transcriptase

Question 14

Parainfluenza virus

Answer 14

Croup, barking seal, pneumonia, syncytia, paramyxovirus

Question 15

RSV

Answer 15

infant, bronchiolitis, paramyxovirus

Question 16

Measles

Answer 16

Koplik’s spots (blue-gray spots in mouth) 3C’s + photophobia, high fever, rash Paramyxovirus

Question 17

Norovirus

Answer 17

Parotitis: chipmunk cheeks

Orchitits pancreatitis and aseptic meningitis or encephalitls

(5%) paramyxovirus

Question 18

Mumps

Answer 18

Parotitis: chipmunk cheeks Orchitits pancreatitis and aseptic meningitis or encephalitls (5%) paramyxovirus

Question 19

Norovirus

Answer 19

Outbreaks of diarrheal disease

Nausea

Watery diarrhea and vomiting

schools

cruise ships

Question 20

Orthomyxovirus

Answer 20

influenza segmented genome = reassortment hemagglutinin and neuraminidase antigenic drift (minor mutations) (outbreak/epidemic) vs shift (reassortment = pandemic)

Question 21

Papillomovirus

Answer 21

warts, koilocyes, CIN, cervical cancer, STD

Question 22

Polyomaviruses

Answer 22

JC, demyelination, abnormal oligodendrocytes, opportunistic disease, PML

Question 23

Parvovirus B19

Answer 23

Fifth disease slapped cheek lacy pattern rash anemia

Question 24

Coxsackie and ECHO viruses

Answer 24

Fecal-oral vesicular lesions Cosackie B for body Picornavirus

Question 25

Poliovirus

Answer 25

Asymmetrical flaccid paralysis major disease minor disease Fecal-oral Picornavirus

Question 26

Rhinovirus

Answer 26

Runny nose, many serotypes, heat and pH labile, picornavirus

Question 27

Poxviruses

Answer 27

Large-brick shaped virus Replicates in cytoplasm vesicular lesion zoonosis molluscum contagiosum: skin-colored papules smallpox: synchronized crop of vesicular lesions (smallpox), vaccinia vaccine

Question 28

Prions

Answer 28

Spongiform encephalopathy, CJD, vCJD, beef, no inflammation, presenile dementia, shakes, resistant to inactivation

Question 29

Rabies

Answer 29

Dog bite bats aerosol hydrophobia coma salivation Negri bodies Rhabdovirus

Question 30

Rotavirus

Answer 30

Watery diarrhea in young child Double capsid and double-stranded segmented RNA

Question 31

Rubella

Answer 31

Rash, vaccine, congenital disease, arthritis, eratogen, cataracts, togavirus

Question 32

Togavirus

Answer 32

Arbovirus Encephalitis viruses: mosquito, seasonal encephalitis, swamps Hemorrhagic viruses: blood everywhere, petechiae

Question 33

Flavivirus

Answer 33

Arbovirus Encephalitis viruses: mosquito, seasonal encephalitis, swamp Hemorrhagic viruses: blood everywhere, petechiae