Virology

Question 1

Soon after interaction with the host cell vision is disrupted infetivity is lost

Answer 1

Eclipse period

Question 2

Virus replication cultured only on

Answer 2

Monkey kidney cell

Duck egg cell

Question 3

Rhinovirus host receptor

Answer 3

ICAM 1

Question 4

HIV host receptor

Answer 4

CD4 +T cells

Question 5

Host receptor

Rabies virus

Answer 5

ACH receptors

Question 6

Host receptor

HSV 1

Answer 6

Fibroblast growth factor receptor

Question 7

Appropriate pH and ionic concentration require counter ion

Answer 7

Magnesium ion

Question 8

Refers to the entry of viral particle into the cytoplasm of the host cell

Answer 8

Penetration

Question 9

Penetration carried out through

Answer 9

Endocytosis ( receptor mediated)
Direct penetration ( viropexis)
Cell fusion ( giant cells )

Question 10

Refers to the physical separation of the viral capsid from the viral genome

Answer 10

Uncoating

Question 11

Steps in viral infection

Answer 11

Attachment and absorption 
Penetration
Uncoating
Early viral mRNA synthesis
Early viral protein synthesis

Question 12

Infectious nucleic acid

If - stranded virus

Answer 12

Non infectious nucleic acid

Question 13

Can bypass the host range specificity provided by the protein host cell receptor interaction

Answer 13

Eg poliovirus

Question 14

1st step in gene expression

Answer 14

mRNA synthesis

Question 15

DNA viruses except ——- replicate in the nucleus , use host cell DNA dependent RNA polymerase synthesize mRNA

Answer 15

Pox virus

Question 16

DNA virus are double stranded

Answer 16

Both + and - strands used as templates

Question 17

Doesn’t have access on the RNA polymerase on host cell nucleus

Answer 17

Pox virus

Question 18

Pox virus should have RNA polymerase

Answer 18

Synthesize mRNA

Question 19

Pox virus replication

Answer 19

Cytoplasm

Question 20

RNA viruses are single stranded

Answer 20

Can be positive or negative

Used as template can synthesize RNA

Question 21

Positive polarity RNA viruses

Answer 21

Picornaviruses
Togaviruses
Flaviviruses

Question 22

Negative polarity

Synthesize own mRNA

Answer 22

Orthomyxovirus
Paramyxovirus
Fill virus
Bunyavarius

Question 23

Negative polarity must be converted to positive strand through

Answer 23

RNA -RNA dependent mRNA -> transcription

Question 24

2 processes of release

Answer 24

Rupture or lysis of cell membrane

Budding through the outer membrane

Question 25

Budding process begin when virus specific proteins enter the cell membrane at specific sites

Answer 25

Herpesviruses - nuclear membrane Pox viruses - inclusion bodies Coronaviruses - endoplasmic reticulum

Question 26

HIV virus / retro virus

Answer 26

Require a DNA intermediate for replication RNA- DNA-RNA

Question 27

Smallest of all microorganism with size ranging from 20-300nm, smallest of which is

Answer 27

DNA virus or parvovirus

Question 28

Smallest RNA virus

Answer 28

Picornavirus

Question 29

Largest and most complex

Answer 29

Poxvirus (also a DNA virus)

Question 30

Do not have structures that compromise the cell

Answer 30

Not cells

Question 31

Almost all viruses are spherical in shape with very few exceptions

Answer 31

Rhabdovirus - bullet shaped Pox virus - brick shaped Bacteriophage - tadpole t shaped Tobacco mosaic virus - rod shaped

Question 32

Viruses posses only one type of nucleic acid

Answer 32

Either DNA or RNA never both

Question 33

Basis for their classification

Answer 33

Nucleic acid

Question 34

They do not have a machinery to produce copies of their own genome. They rely on their host cell for its energy -yielding apparatuses

Answer 34

Obligate intracellular parasites

Question 35

Multiply through the process of

Answer 35

Replication

Question 36

Viruses doesn't have

Answer 36

Cell wall and ribosomes that ps why antibiotics is not effective

Question 37

Not only viruses can induce interferon production but other bacteria like rickettsia

Answer 37

Not virus specific

Question 38

Most of the viruses are haploid, cainta ins one canopy of their genes except

Answer 38

Retroviruses that are diploid

Question 39

Composed of nucleic acid , viral genome

Answer 39

Core

Question 40

Surround the viral genome

Answer 40

Capsid

Question 41

Capsid composed of repeating subunits known as

Answer 41

Capsomeres

Question 42

Capsid can assume any symmetry

Answer 42

Icosahedral - 20 small triangle | Helical - arranged in hallow coil that appear rod shaped

Question 43

Outside the viral capsid composed of lipoprotein that are derived from the viral host cell membrane

Answer 43

Envelope

Question 44

Viruses with envelope

Answer 44

Enveloped viruse

Question 45

Virus without envelope

Answer 45

Naked viruses

Question 46

Paano mo masasabi na complet e pag naked

Answer 46

May nucleic acid | Capsomeres or viral capsid

Question 47

Paano naman kung envelope virus

Answer 47

Envelope Nucleic acid Capsomeres or capsid

Question 48

Particle that contains the host cell DNA instead of a viral DNA

Answer 48

Pseudovirion

Question 49

Particles consist solely of a single molecule of circular RNA without a protein coat or envelope

Answer 49

Viroids

Question 50

Infectious protein particles composed solely of proteins

Answer 50

Prions

Question 51

Example of prions

Answer 51

Mad cow

Question 52

Double stranded DNA except

Answer 52

Parvovirus

Question 53

Naked except

Answer 53

Herpes Hepadna Pox virus

Question 54

Icosahedral symmetry except

Answer 54

Poxviruses

Question 55

Replicate in the nucleus of the host cell except

Answer 55

Pox viruses which replicate in the cytoplasm of the host cell

Question 56

SS RNA except

Answer 56

Reovirus

Question 57

Enveloped except

Answer 57

Reovirus | Picornavirus

Question 58

Helical symmetry except

Answer 58

Reovirus Picornavirus Flavivirus Togavirus

Question 59

Replicate in the cytoplasm except

Answer 59

Orthomyxovirus | Retroviruses

Question 60

Table in family, envelope, symmetry, DNA structure and important viruses

Answer 60

Nasa trans

Question 61

Viruses multiply only

Answer 61

In living cells