Virology Blitz

Question 1

Enveloped DNA viruses

Answer 1

Herpes, Hep B and Smallpox

Question 2

Nonenveloped DNA virus

Answer 2

Parvo-, adeno-, papilloma-virus

Question 3

Nonenveloped RNA viruses

Answer 3

Entero, rhino and reo

Question 4

Enveloped RNA virus

Answer 4

Influenza and parainfluenza, RSV, MMR, rabies, HTLV, HIV

Question 5

Acute febrile illness associated with abrupt onset of HA, myalgias, fever leading to rash, shock, and bleeding

Answer 5

Ebola

Question 6

Mammalian filamentous virus

Answer 6

Ebola virus

Question 7

Filoviruses such as Marburg virus and Ebola virus can cause what disease?

Answer 7

Hemorrhagic fevers

Question 8

Biosafety level of Ebola and Marburg virus

Answer 8

Level 4

Question 9

Ebola virus specie in the Philippines

Answer 9

Reston

Question 10

Monkey for Reston (Ebola virus)

Answer 10

Cynomolgus Macaques

Question 11

Incubation period of 7-10 days
Flu-like sxs continued fever joined by diarrhea, chest pain (associated with cough), prostration, depressed mentation with maculopapular rash (day5-7) followed by desquamation

Answer 11

Ebola virus

Question 12

Herpangina, HFMD are caused by what virus

Answer 12

Coxsackie Also

Question 13

Pleurodynia (Bornholm disease), myocarditis, pericarditis are caused by what virus?

Answer 13

Coxsackie B

Question 14

Group of rotavirus that is the principal cause of human disease

Answer 14

Group A rotavirus

Question 15

Groups of rotavirus that are known to cause disease in humans

Answer 15

Groups A, B, C

Question 16

Virus that is the leading cause of morbidity among Filipino children and 5th leading cause of infant mortality

Answer 16

Rotavirus

Question 17

Gold standard for diagnosing rotavirus

Answer 17

Viral culture

Question 18

4 conditions that are associated with Parvoviridae

Answer 18

Erythema infectiosum
Pure red cel aplasia
Transient aplastic crisis
Hydrops fetalis

Question 19

Slapped cheek appearance + lacy appearing rash

Answer 19

Erythema infectiosum, fifth’s disease, parvovirus B19

Question 20

HHV6, 6th disease, exanthem subitum, 6months to 2 years

Answer 20

Roseola

Question 21

Only DNA virus that replicates in the cytoplasm

Answer 21

Poxvirus

Question 22

Poxvirus infection that is more virulent

Answer 22

Variola

Question 23

Poxvirus infection that is less virulent

Answer 23

Vaccinia

Question 24

Who introduced vaccination with live cowpox virus in 1798?

Answer 24

Edward Jenner

Question 25

Control of smallpox by deliberate infection with mild forms (i.e. Vaccinia) of the disease

Answer 25

Variolation

Question 26

Inclusion bodies in Small pox

Answer 26

Guarnieri bodies

Question 27

Inclusion bodies of Rubeola

Answer 27

Warthin finkeldey bodies

Question 28

Inclusion bodies of Molluscum contangiosum

Answer 28

Henderson-Peterson bodies

Question 29

Dermatome affected in Shingles

Answer 29

Thoracic

Question 30

Tzanck smear is an assay used for:

Answer 30

HSV and VSV

Question 31

DOC for CMV

Answer 31

Ganicyclovir

Question 32

Heterophile positive | Heterophile negative

Answer 32

Heterophile positive EBV | Heterophile negative CMV

Question 33

Monospot test or Heterophile antibody test (Paul-Bunnel) is diagnostic of what disease?

Answer 33

Infectious mononucleosis

Question 34

What to look for Monospot test?

Answer 34

Agglutination of RBCs

Question 35

HHV8 is associated with what conditions?

Answer 35

Kaposi sarcoma, AIDS associated B-cell lymphoma, multiple myeloma

Question 36

Primary method for detection of HHV8

Answer 36

PCR amplication

Question 37

Enzyme used for PCR amplication

Answer 37

Taq polymerase (heat stable enzyme)

Question 38

HPV16 and HPV18 associated in CIN mechanism

Answer 38

Inactivation of tumor suppressor proteins p53 and p110-Rb by viral protein E6 and E7

Question 39

HPV 1, 2, 4 causes?

Answer 39

Plantar warts

Question 40

Exanthematous phase of measles

Answer 40

Red maculopapular eruption beginning on forehead (around the hairline), behind the ears, and on upper neck spreading downwards to the torso and extremities

Question 41

Most common complication of measles

Answer 41

Otitis media