Virology Memorization

Question 1

What vaccines are live attenuated viruses?

Answer 1

1. Smallpox
2. Yellow Fever
3. Sabin Polio (OPV)
4. MMR
5. Nasal Flu

Question 2

What vaccines are killed viruses?

Answer 2

1. Rabies
2. Injected Flu
3. HAV

Question 3

What type of vaccine is HBV?

Answer 3

Recombinant - HBsAg

Question 4

What type of vaccine is HPV?

Answer 4

Recombinant - HPV 6, 11, 16, 18

Question 5

What viruses have DNA genomes? Which one is ss?

Answer 5

Herpesviruses - HSV, EBV, CMV, VZV
Hepadnevirus - HBV
Adenovirus
Parvovirus (ss) - B19
Papillomavirus - HPV
Polyomavirus - JC, BK
Poxvirus - Smallpox, vaccinia (cowpox), m. contagiosum

HHAPPPPy viruses

All are ds except Parvo (ss)

Question 6

What DNA viruses have a circular genome?

Answer 6

Papillomavirus (HPV)
Polyomavirus (JC and BK)
Hepadnavirus (HBV)

Question 7

What is the only dsRNA virus?

Answer 7

Reovirus (repeatovirus)

Question 8

Are viruses haploid or diploid?

Answer 8

All are haploid except HIV (which is diploid - two identical copies of ssRNA genome)

Question 9

What is the only DNA virus to replicate in the cytoplasm?

Answer 9

Poxviruses (smallpox, vaccinia, m. contagiosum)

Question 10

What is the only RNA virus to replicate in the nucleus?

Answer 10

Influenza

Question 11

Where do enveloped viruses get their envelope?

Answer 11

From plasma membrane, except herpesviruses (gets it from the nuclear membrane)

Question 12

What are the naked viruses?

Answer 12

Papilloma
Adeno
Picorna
Polyoma
Calci
Parvo
Reo
Hepevirus

“PAPP smears and CPR for NAKED Heppy (hippy)”

Question 13

DNA viruses?

Answer 13

Hepadna
Herpes
Adeno
Pox
Parvo
Papilloma
Polyoma

“HHAPPPPy viruses”

Question 14

What are the polyomaviruses?

Answer 14

JC - PML in HIV pts

BK - kidney dz in transplant pts

Question 15

What are the pox viruses?

Answer 15

Smallpox
Vaccinia (cowpox)
Molluscum contagiosum

Question 16

What is the Hepadnavirus?

Answer 16

HBV

Question 17

What is the parvovirus? What does it cause?

Answer 17

B19 - “slapped cheek” 5th disease; aplastic crisis in Sickle cell dz

Question 18

What is the largest DNA virus?

Answer 18

Pox - replicates in cytoplasm

Question 19

What virus can cause temporal lobe encephalitis?

Answer 19

HSV-1

Question 20

Mononucleosis?

Answer 20

EBV (+ monospot) and CMV (- monospot)

Question 21

What virus causes roseola?

Answer 21

HHV-6, high fever for days then diffuse rash

Question 22

What virus causes Kaposi?

Answer 22

HHV-8

Question 23

Owl’s eye inclusions?

Answer 23

CMV

Question 24

Test of choice for HSV dx?

Answer 24

PCR

Question 25

Tzanck smear?

Answer 25

HSV-1, -2, VZV

Question 26

What cells do EBV infect? Via what?

Answer 26

B cells via CD21

Question 27

Atypical lymphocytes in mono are what?

Answer 27

REACTIVE CYTOTOXIC T CELLS (not infected B cells)

Question 28

What kind of virus is norovirus?

Answer 28

Reo, so it is dsRNA

Question 29

What are the picornaviruses?

Answer 29

PERCH ``` Polio Echo Rhino Coxsackie HAV ```

Question 30

What are the - sense RNA viruses?

Answer 30

``` Arena Bunya Paramyxo Orthomyxo Filo Rhabdo ```

Question 31

What are the + sense RNA viruses?

Answer 31

``` Picorno Hepevirus Calici Flavi Toga Retro Corona ```

Question 32

What are the hepeviruses?

Answer 32

HEV

Question 33

What are the flaviviruses?

Answer 33

``` HCV Yellow fever Dengue St. Louis West Nile ```

Question 34

What are the togaviruses?

Answer 34

Rubella | Eastern/Western equine encephalitis

Question 35

What are the retroviruses?

Answer 35

HTLV | HIV

Question 36

What are the coronaviruses?

Answer 36

coronoavirus - SARS/common cold

Question 37

What are the orthomyxoviruses?

Answer 37

Influenza

Question 38

What are the paramyxoviruses?

Answer 38

Parainfluenza - croup RSV Measles Mumps

Question 39

What are the rhabdoviruses?

Answer 39

Rabies

Question 40

What are the filoviruses?

Answer 40

Ebola

Question 41

What are the Arenaviruses?

Answer 41

LCMV | Lassa fever

Question 42

What are the bunyaviruses?

Answer 42

California encephalitis Sandlfy/Rift valley fever Crimean-Congo hemorrhagic fever HANTAVIRUS --> ARDS

Question 43

What are the deltaviruses?

Answer 43

HDV

Question 44

How are picornaviruses spread?

Answer 44

All by fecal-oral except rhinovirus (which is acid labil)

Question 45

Common cold?

Answer 45

Rhino virus

Question 46

Infantile gastroenteritis?

Answer 46

Rotavirus

Question 47

Rash that starts on head and moves down?

Answer 47

Rubella (part of ToRCHeS)

Question 48

All paramyxoviruses have what? What is the tx?

Answer 48

F protein (Fusion) Palivizumab = mab for F protein

Question 49

What is the target of tamiflu?

Answer 49

Neuramidase

Question 50

Koplik spots?

Answer 50

Red spots whit white center on buccal mucosa Measles

Question 51

What is a long term sequelae of measles?

Answer 51

SSPE - subacute sclerosing panencephalitis

Question 52

What are the symptoms of Mumps?

Answer 52

Parotitis Orchitis Meningitis Parotid and testes as bigs as POM-poms

Question 53

How does HCV change its antigens?

Answer 53

Lacks 3'-->5' endonuclease so it is prone to mistakes.

Question 54

What is the clinical definition of AIDS?

Answer 54

CD4+ less than 200 or an AIDS defining infection