Virology past questions Flashcards

1
Q

Polyomavirus causes latent infections

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Adenovirus causes enteritis in mammals/birds

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The morphology of Adenovirus?

A
  • medium-sized
  • non-enveloped (without outer lipid bilayer) viruses
  • icosahedral nucleocapsid
  • dsDNA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What type of virus is Varicella Viruses?

A

Herpesvirales (alpha)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pox virus causes skin lesions

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Capripox cause skin lesions

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of virus is Hepadnviridae – VtRT – ?

A

DNA virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The morphology of Circoviridae?

A
  • circular ssDNA
  • 20nm icosahedral capsid
  • non enveloped
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Parvo causes enteritis

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How is the transmission of Birnaviridae?

A

By contact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Rotavirus causes neonatal enteritis

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the host of Teschovirus?

A

Pigs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does Parechovirus cause?

A

Enteritis - inflammation of small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dicistroviridae is a virus of honey bees

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Avastrovirus causes what in chickens?

A

Nephritis – inflammation of the kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How is rabbit haemorrhagic disease transmitted?

A

Direct contact with infected animal or fomite(nonliving object capable of carrying infectious organisms)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Border disease causes abortion in sheep

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Arteriviridae affect stallions

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

The Influenza host(avian)?

A

Wild water birds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The surface protein of Influenza?

A

Hemagglutinin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Parainfluenza virus 3 infects?

A

cattle, sheep – “shipping fever”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What type of virus is canine distemper virus?

A

Morbillivirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Cowpox/pseudocowpox is zoonotic

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Herpes virus is an arbovirus(transmitted by insects)

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What does herpesvirus cause?

A

Disease, lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

How is ephemerovirus transmitted?

A

By mosquito

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Nairovirus is an arbovirus

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What lesions does a retrovirus cause?

A

Lesions in skin and brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

TSE(transmissible spongiform encephalopathies) affect mainly cattle/minks/cats

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Prions are resistant to proteases

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Name of TSEs(transmissible spongiform encephalopathies) in sheep?

A

Scrapie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

African horse sickness is caused by which virus?

A

Orbivirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Genera of the Picornaviridae are?

A

Entro-, Tescho-, Hepato-, Avihepato-, Tremo-, Cardio-, Aphtho-, Erbo-, Parecho-, Kobuvirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Alphaviruses:

A) Transmitted by ticks
B) May be zoonotic
C) Only present in America
D) Do not show cross reaction

A

B) May be zoonotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Torovirus can cause?

A

Chicken, swine and human gastroenteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Reservoir host of mamastrovirus?

A

Human, mammals and verterbrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Human and bovine pathogen viruses are found in the:

A) Alpha
B) Beta
C) Gamma

A

A) Alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Prion pathogens does not contain?

A

Nucleic acid - proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Animals are susceptible to:

A) Mumps
B) Measles
C) Influenza 1

A

C) Influenza 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Affinity chromatography uses?

A

Separating biochemical mixtures, adsoption of viruses, rinsing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Lesions caused by Pox on CAM embryonic egg are called?

A

Vesicular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Which disease was recently eradicated from earth?

A

Rinderpest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Kidney lesions in chickens are caused by?

A

Avastrovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

How did virus get its name?

A

A scientist used a filter that had smaller pores than bacteria, and found out that the filtered solution contained a new form of infectious agent. He observed that the agent multiplied only in cells that were dividing, but as his experiments did not show that it was made of particles, he called it a contagium vivum fluidum (soluble living germ) and re-introduced the word virus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Prions causes what in sheep?

A

Scrapie, TSE’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

How is airborne viruses contracted?

A

Via the respiratory tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

The host of Hantavirus?

A

Rodents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

What is given name for goose disease?

A

Goose parvovirus – Derzsy’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Adeno and orthomyxo viruses, name disease for calves

A

Pneumoenteritis for calves(Influenza)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

What does Aujesky disease cause in canines?

A

Lethal CNS disease(deadly encephalitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

True/False on immunosuppression:

Leakaemia
Lymphocytes
Enterocytes
Encephalomyelitis

A

Leakaemia TRUE
Lymphocytes FALSE
Enterocytes TRUE
Encephalomyelitis TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

What virus is propagated in Chorio Allantoin?

A

Pox-, herpesvirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

What is eclipse?

A

Specific, depends on the nucleic acids that the virus contains- expression of genetic information, transcription, translation and nucleic acid replication – a step in virus multiplication.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

What is it called when virus enters the blood?

A

Viremia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Genetic part of virion?

A

DNA/RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

The role of Rdrp in retrovirus?

A

Replication of RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

How do bacteriophage get into host cell?

A

Penetration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

What is prions?

A

Prions are proteins that reproduce on their own and become infectious

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Virions always contain lipids

A

FALSE

60
Q

Virions with quasihelical nucleocapsid are enveloped

A

TRUE

61
Q

Virions with icosahedral capsid are never enveloped

A

FALSE

62
Q

Pleomorphic viruses may not have nucleocapsid

A

TRUE

63
Q

Please mark which statement is true:

A) Mutations are more frequent in cellular organisms than in viruses
B) The effects of mutations are always advantageous for the viruses
C) Mutation may alter the host specificity of a virus
D) Mutant viruses cannot be used as vaccine strains

A

C) Mutation may alter the host specificity of a virus

64
Q

How do we call the process when the antigenic structure of a virus suddenly changes due to reassortment?

A

Antigenic shift

65
Q

Polyomaviruses may cause persistant infections in kidney cells

A

TRUE

66
Q

Papillomaviruses often cause encephalitis and diarrhea in swine

A

FALSE

67
Q

Serological cross-reactions may occur between adenovirus species within the same genus

A

TRUE

68
Q

Atadenovirses may cause disease in birds

A

TRUE

69
Q

Please mark which statement is true
The Aujeszky’s disease is caused by the:

A) Suid herpesvirus type 1
B) Canid herpesvirus type 2
C) Porcine parvovirus type 1
D) Porcine circovirus type 2

A

A) Suid herpesvirus type 1

70
Q

Which virus family contains viruses with positive sense, single-stranded RNA genome and helical capsid?

A

Coronaviridae

71
Q

What virus cause abortions?

A

Varicellovirus, Orbivirus, Flavivirus, Equine arteritis virus, Phlebovirus

72
Q

How does the enveloped virus enter the cell?

A

Membrane fusion

73
Q

Virus can only propagate in living cells

A

TRUE

74
Q

What disease is caused in hen by astrovirus?

A

“White chicks” condition

75
Q

What kind of theories of the origin of viruses are there?

A
  1. Cell degeneration

2. Cell autonomy

76
Q

Which of the following is direct virus detection?

A

Virus isolation: EM, IF, NA hybridisation, HA

77
Q

Where do you inject Blue tongue virus?

A

Intravenously into embryonated hen egg

78
Q

Which area of the embryonate egg do we use for haemagglutination test?

A

Allantoic fluid

79
Q

What does a ‘medium’ contain?

A

Salts, amino acids, carbohydrates, indicator, antibiotics and antimimetikum

80
Q

What is Trypsin-EDTA used for?

A

Digestion between the cells of in vitro tissue culture

81
Q

Are there cancer cell cell cultures?

A

Yes, aneuploid cell culture

82
Q

What is a buffy coat?

A

White blood cell culture

83
Q

Virus extraction methods?

A
  1. Freezing-thawing three times
  2. Ultrasound
  3. Detergent
84
Q

With what is virus concentration by precipitation possible?

A

Ammonium sulphate, PEG, alcohol

85
Q

Are there definitely lipids in virions?

A

Definitely not, because they are found in the external layer/envelope

86
Q

Are quasi helical viruses always enveloped?

A

Yes

87
Q

What is characteristic of complex viruses?

A

No capsomere, complete symmetry (pox virus)

88
Q

Pleomorph viruses have no nucleocapsid

A

True

89
Q

What can we label Nucleic acid hybridisation samples with?

A

Isotopes or enzymes

90
Q

What can we show with PCR?

A

Nucleic acids

91
Q

What is needed for sequencing?

A

Primer, template, deoxynucleotides and marked dideoxynucleotides

92
Q

What cells are formed with the fusion of myeloma and B-cells?

A

Tetraploid hybrid cells

93
Q

Non-structural proteins do not integrate into the virion

A

TRUE

94
Q

What is budding?

A

A type of enveloped virus release

95
Q

Are mutations only a disadvantage?

A

No, they can be advantageous

96
Q

Can the external environment influence mutation?

A

Yes

97
Q

Where are there more mutations?

A

there are 10^9 in cells and 10^3 in DNA viruses 10^3 so there are more in RNA viruses

98
Q

With mutation, can species-specificity change?

A

Yes

99
Q

Are clutters thanks to/as a result of Interleukins?

A

No

100
Q

Is autointerference autoimmune?

A

No

101
Q

What is the reception of structural proteins?

A

Mixing of phenotypes

102
Q

Do two attenuated vaccines activate each other?

A

Yes

103
Q

Does intramolecular recombination only happen in DNA viruses?

A

No

104
Q

What causes cell cracking?

A

Depolarisation of the cytoskeleton

105
Q

How can you send samples?

A

Via courier, with exact legible details, +4°C, exact address

106
Q

What vectors spread rabbit haemorrhage fever?

A

Mosquitoes

107
Q

What infects bees?

A
  1. Dicistroviridae (Aparavirus: acute paralysis, acute Israeli paralysis, Kashmar paralysis, Cripavirus: black mother-pearl virus)
  2. Iflaviridae family (larvae cystic and wing deformity virus)
108
Q

What form does herpes latency appear as in the nucleus?

A

Episome (ganglion, gland, macrophage, lymphocyte)

109
Q

All Bunyaviridae are arboviruses

A

FALSE

110
Q

After taking samples, the samples have to be sent to the lab within how many hours?

A

Usually 24 hours (leukocytes: 6 hours)

111
Q

When are swab samples used?

A

With body fluid sample

112
Q

When can mutations happen?

A

During viral eclipse

113
Q

Are there any immune response during tolerated infections?

A

No

114
Q
Experimental animals can be used to spread viruses for:
 Diagnostic purposes
 Vaccine production
 Vaccine control/checks
 Cell line production
A

TRUE - Diagnostic purposes
TRUE - Vaccine production
TRUE - Vaccine control/checks
FALSE - Cell line production

115
Q

With Cell culture passage:

We can keep up/maintain breeding
We can increase the quantity of cell breeding/cultures
We can remove contaminated viruses
We can remove tumour cells

A

TRUE - We can keep up/maintain breeding
TRUE - We can increase the quantity of cell breeding/cultures
FALSE - We can remove contaminated viruses
FALSE - We can remove tumour cells

116
Q

The polymerase chain-reaction contains:

Sample (virus) DNA
Temperature resistant (Taq) DNA polymerase
Virus-specific oligonucleotide primers
Virus-specific monoclonal antibodies

A

TRUE - Sample (virus) DNA
TRUE - Temperature resistant (Taq) DNA polymerase
TRUE - Virus-specific oligonucleotide primers
FALSE - Virus-specific monoclonal antibodies

117
Q

Disinfectants:

Always damage the viral nucleic acid
Only act against enveloped viruses
Can be used in the environment or outer/external cover
Occasionally toxic or corrosive

A

FALSE- Always damage the viral nucleic acid
FALSE - Only act against enveloped viruses
TRUE - Can be used in the environment or outer/external cover
TRUE - Occasionally toxic or corrosive

118
Q

TRUE/FALSE:

Acridine orange turns the single-stranded nucleic acid orange/red.
With polymerase chain-reaction we can determine the infective titer of the virus.
With the virus neutralisation test we can separate the maternal and vaccine-induced antibodies.
With the haemagglutination inhibition test, we can show the African swine fever antibodies.

A

TRUE - acridine orange turns the single-stranded nucleic acid orange/red
FALSE - with polymerase chain-reaction we can determine the infective titer of the virus
FALSE - with the virus neutralisation test we can separate the maternal and vaccine-induced antibodies
FALSE - with the haemagglutination inhibition test, we can show the African swine fever antibodies

119
Q

What can we call the process where the cell division of cells of ectopic tissues are inhibited during contact?

A

Contact inhibition

120
Q

What is the concentration mode in which, with the help of osmotic pressure, water is removed from the virus suspension?

A

Dialysis

121
Q

What do we call the virus penetration method, whereby RNA-protein complexes can pass through the cytoplasmic membrane?

A

Translocation

122
Q

What is it called, when an mRNA codes for more than one protein?

A

Polycystronic

123
Q

What do we call the type of phenotypic mix, when one of the virus’ nucleic acids builds into the other virus’ capsid?

A

Phenotypic mixing(melange)

124
Q

What is the name of the method whereby, organ samples of dead animals are inoculated for cell cultures?

A

Cell cultivation or cell culture contamination

125
Q

What is the name of the virus detection method whereby, the antigen and antibody react with one another via an electric current?

A

(Electric current) immunoelectrophoresis

126
Q

What do we call an the ingredients of an inactive vaccine, which increases the vaccine intensity?

A

Adjuvant

127
Q

What kind of virus are usually Papilloma viruses?

A

Stenoxen viruses

128
Q

What does Alpha herpes viruses cause?

A

Latency in ganglionic nervecells

129
Q

What does Orthopox viruses cause?

A

Cowpox virus

130
Q

Beak and feather disease viruses have an immunosuppressive effect

A

TRUE

131
Q

Orthoreo viruses cause tenosynovitis in birds

A

TRUE

132
Q

The Ebola virus can cause bleeding fever in humans

A

TRUE

133
Q

The environmental owners/maintainers of the Mamaerena viruses are?

A

Rodents

134
Q

Viruses affecting humans and cattle?

A

Deltaretrovirus genus

135
Q

How are prion proteins usually spread?

A

Orally

136
Q

Which virus can cause kidney failure in chickens?

A

Gammacoronavirus (infectious bronchitis)

137
Q

Which virus causes a slowly-developing infection in horses?

A

Influenza virus

138
Q

Causes immunosuppression in cats:

Panleicopenia virus
Peritonitis virus infecting cats
Feline leukaemia virus
The infectious bursitis virus

A

FALSE - Panleicopenia virus
TRUE - Peritonitis virus infecting cats
TRUE- Feline leukaemia virus
FALSE - The infectious bursitis virus

139
Q

Causes abortion, respiratory and central nervous system symptoms:

Herpresmamillitis virus (BoHV-2)
Cattle affecting infectious rhinotracheitis virus (BoHV-2)
Equine rhinopneumonitis virus (EHV-1)
Aujeszky-disease virus (SuHV-1)

A

FALSE- Herpresmamillitis virus (BoHV-2)
TRUE- Cattle affecting infectious rhinotracheitis virus (BoHV-2)
TRUE - Equine rhinopneumonitis virus (EHV-1)
TRUE - Aujeszky-disease virus (SuHV-1)

140
Q

Small mammals are the hosts of:

Mammalian bornavirus
Mammaerenavirus
Mamastroviruses
Hantaviruses

A

TRUE - Mammalian bornavirus
TRUE - Mammaerenavirus
FALSE - Mamastroviruses
TRUE- Hantaviruses

141
Q

What is the name of the illness/disease caused by rhinovirus?

A

Rhinitis

142
Q

In what species does Border disease virus cause illness?

A

Sheep

143
Q

Which virus causes persistent infections in the sexual organs/tracts?

A

Arterovirus

144
Q

Which animal virus did they manage to get rid of on Earth?

A

Eastern cowpox and Morbillivirus

145
Q

Which virus causes glandular stomach disease in parrots?

A

Bornavirus

146
Q

What do they call the virus causing human immunodeficiency?

A

AIDS