Virulence Factor actions Flashcards Preview

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Flashcards in Virulence Factor actions Deck (18):
1

icam 1

allows binding to human cells

2

capsule

prevents phagocytosis

3

lipooligosacch

helps cells bind to non-ciliated epithelial cells

4

fungal spores

phagocytes of IC not fast enough!
spores germinate and penetrate host tissue== necrosis :(

5

hyaluronic acid capsule

prevents phagocytosis

6

m protein

prevents phagocytosis

7

Spe A-C, erythrogenic toxin A-C

damage capillary walls= scarlet fever

these toxins are super Ag that stim immune cells and cause toxic shock

8

M protein in RHD

protein in antigenic and Bcells make Ab to m protein... these ab also react with heart proteins

9

Diphtheria toxin

ADP ribosylation of host cell elgongation factor

10

CX3CR1 or heparin sulfate

allows RSV to bind and infect human cells

11

flu hemagglut and neuramindase

hemaglutt: bind to host cells

neuram: helps mature flu escape host cells

12

Shift

change in type of H/N

13

drift

mutation in H/N

14

pertussis filamentous hemagglut

attachment to ciliated epithelial cells

15

pertussis cytotox

kills cells that line trachea

16

pertuss toxin

ADP ribosylating G protein, causes majority of tracheal cell damage

17

myco plas cytadherence organelle

adhere to ciliated columnar epithelial airway cells

18

pseudomonas alginate production

exopolysacch that allows binding to host cells. part of biofilm matrix which protects cells from phagocytosis