Virulence Factor actions Flashcards Preview

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Flashcards in Virulence Factor actions Deck (18)
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1
Q

icam 1

A

allows binding to human cells

2
Q

capsule

A

prevents phagocytosis

3
Q

lipooligosacch

A

helps cells bind to non-ciliated epithelial cells

4
Q

fungal spores

A

phagocytes of IC not fast enough!

spores germinate and penetrate host tissue== necrosis :(

5
Q

hyaluronic acid capsule

A

prevents phagocytosis

6
Q

m protein

A

prevents phagocytosis

7
Q

Spe A-C, erythrogenic toxin A-C

A

damage capillary walls= scarlet fever

these toxins are super Ag that stim immune cells and cause toxic shock

8
Q

M protein in RHD

A

protein in antigenic and Bcells make Ab to m protein… these ab also react with heart proteins

9
Q

Diphtheria toxin

A

ADP ribosylation of host cell elgongation factor

10
Q

CX3CR1 or heparin sulfate

A

allows RSV to bind and infect human cells

11
Q

flu hemagglut and neuramindase

A

hemaglutt: bind to host cells
neuram: helps mature flu escape host cells

12
Q

Shift

A

change in type of H/N

13
Q

drift

A

mutation in H/N

14
Q

pertussis filamentous hemagglut

A

attachment to ciliated epithelial cells

15
Q

pertussis cytotox

A

kills cells that line trachea

16
Q

pertuss toxin

A

ADP ribosylating G protein, causes majority of tracheal cell damage

17
Q

myco plas cytadherence organelle

A

adhere to ciliated columnar epithelial airway cells

18
Q

pseudomonas alginate production

A

exopolysacch that allows binding to host cells. part of biofilm matrix which protects cells from phagocytosis