VIRUS Flashcards

(27 cards)

0
Q

Salk

A

first vaccine for polio

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1
Q

Jenner

A

discovered first vaccine

scratched cow pox into son to give immunity to small pox

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2
Q

Pasteur

A

discovered vaccine for rabies

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3
Q

Sabin

A

discovered oral vaccine for polio

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4
Q

ways to keep the immune system healthy:

A

healthy eating

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5
Q

capsid

A

rigid protein shell which protects the genetic code

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6
Q

capsomere

A

protein building block which binds with others to make up a capsid

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7
Q

viral envelope

A

outer cloak made of fat (from the ruptured cell of a host)

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8
Q

protease

A

special chemical used to cut up protein chains into usable lengths

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9
Q

DNA virus

A

contains DNA who’s genetic code is copied into viral RNA

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10
Q

RNA virus

A

contains RNA which is released directly into the ribosomes

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11
Q

retro virus

A

transcripts viral RNA into DNA and then back into RNA

HIV

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12
Q

why is retro virus the most lethal?

A

it inserts itself directly into the cells genome so it is there forever

there is a greater chance of mutations

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13
Q

4 groups of viruses?

A

plant, animal, bacterial, amoeba

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14
Q

3 groups of viruses based on genetic content?

A

DNA, RNA, retro

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15
Q

structures within an HIV virus?

A

gp120, gp41, p17, p24, RNA, reverse transcriptase, protease, integrase

16
Q

glycoprotein 120

A

120000 H atoms
on outer surface of virus
VAP which attaches to CD4 receptors of the white blood cell (Helper Tcell)

17
Q

glycoprotein 41

A

41000 H atoms
within outer envelope
anchors gp120 to membrane of virus

18
Q

protein 17

A

capsid (capsomeres (protein))
beneath surface of envelope
protective shell of p24

19
Q

protein 24

A

smaller cone-shaped capsid (capsomeres)
inside p17
builds protective shell for genetic code

20
Q

RNA

A
nucleic acid (2 strands)
inner capsid
constructs viral protein
21
Q

reverse transcriptase

A

enzyme
inner capsid; attached to RNA
transcribes code from RNA to DNA; allows for mutations

22
Q

protease

A

enzyme; special chemical scissors
inner capsid
cuts viral protein into usable lengths

23
Q

integrase

A

enzyme; chemical scissors
inner capsid
cuts host DNA and inserts viral code

24
viral replication steps
1. recognition 2. attachment 3. penetration 4. uncoating 5. latent cycle 6. lytic cycle 7. modification 8. assembly 9. lysis
25
recognition
VAP recognizes receptor of host cell
26
attachment
VAP binds to cell receptor