Virus SSTI Flashcards

(48 cards)

1
Q

Papillomas Nodules

A

Warts

Molluscum

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2
Q

Warts

A

HPV

Papovaviridae family

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3
Q

Molluscum Contagiosum

A

Molluscum Contagiosum Virus

Poxyviridae family

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4
Q

Ulcers and purulent lesions

A

Herpes labialis
Chicken pox
Herpes zoster/ shingles
Small pox

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5
Q

Cold sores

A

Herpes labialis
Herpes simplex virus
Herpesviridae family

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6
Q

Chicken pox

A

Varicella zoster virus

Herpesviridae family

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7
Q

Herpes Zoster

A

Shingles
VZV reactivation
Herpesviridae family

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8
Q

Small pox

A

Variola virus

Poxiviridae family

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9
Q

Childhood rash & fever

A

Measles
German measles
Fifth disease / Erythema
Roseola infantum

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10
Q

Rubeola

A

Measles
Measles Virus
Paramyxovirus familly

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11
Q

German Measels

A

Rubella Virus

Togaviridae

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12
Q

Erythema infectiosum

A

Fifth Disease
B19 Parvovirus
Parvoviridae

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13
Q

Roseola infantum

A

HHV 6 & 7

Herpesviridae

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14
Q

HPV

A

Non enveloped dsDNA
Replication tied to tissue infected
Expansion of epithelial layer

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15
Q

HPV VF

A

E7 inhibits RB
E6 inhibits p53
100 serotypes

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16
Q

HPV Transmission

A

Direct contact cut/abraisons
New HPV virions form in
suprabasal layer of skin

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17
Q

HPV symptoms

A

Warts exophytic
Plantar warts
Punctate hemorrhage
Flat warts mouth

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18
Q

HPV Diagnose and treat

A
Clinical signts: Hyperkeratosis & Koilodal cells.
Cryotherapy
Cytotoxic chemical
Surgical removal
HPV vaccine 16 & 18
not cutaneous
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19
Q

MCV

A

Large dsDNA

Replicates in cytoplasm

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20
Q

MCV Transmission

A

Direct contact w/ lesion
STD
On face or genitals

21
Q

MCV Symptoms

A

Painless pearly nodules
Central depression purulent fluid
Molluscum bodies

22
Q

MCV Diagnose & Treat

A

Signs
Resolves w/ out or
Surgery cryotherapy

23
Q

HSV

A

Enveloped dsDNA
Latent n Lytic
HSV 1 oral
HSV 2 genital

24
Q

HSV Transmission

A

Direct contact w/ lesion or saliva.
Follows PNS
TGG

25
HSV Symptoms
1. cold sore 2. recurrent Simplex keratitis blindness Whitlow neonates toes Encephalitis
26
HSV Treat
Acyclovir
27
Varicella zoster virus
Enveloped dsDNA
28
VZV transmision
Resp secretions Saliva Direct contact
29
VZV Symptoms
Lesion mostly in trunk face and scalp Vesicle - postules - scabs Bacterial infection of lesions Pnuemonia or dissemination
30
VZV Diagnose & Treat
``` Signs Serology Vaccine - LIVE ATTENUATED Also helps against SHINGLES Acyclovir ```
31
VZV Shingles Symptoms
Paresthesia prodrome vesicular lesions on trunk unilateral fever malaise Postherpetic neuralgia
32
Variola virus
Large dsDNA Replicates in cytoplasm Own enzymes Strictly human
33
Variola Transmission
Aerosol Contact lesion Contagious until all scabs cleared
34
Variola symptoms
``` Abrupt high fever Malaise headache Myalgia nausea Lesion on mouth & skin Centrifugal and On palms and soles Resp tract Encephlitis Hemorrhagic Mortality higher ```
35
Variola Diagnose & treat
Vaccine LIVE ATTENUATED Eradicated
36
Measles Virus
Enveloped ssRNA F gene fusion HA attachement
37
Measles Transmission
Resp. shed in nasopharynx Highly contagious Infect up to 2 hr in air
38
Measles symptoms
``` Cough Coryza Conjunctivitis Kopliks spots Annorhexia, diarrhea otitis media, pneumonia encephalitis seizures and death ```
39
Measles diagnose & treat
Immuno prophalaxis Vaccine LIVE ATTENUATED
40
Rubella Virus
Enveloped | +ssRNA
41
Rubella transmission
Resp
42
Rubella signs
Maculopapular rash 1st face and the downward Fainter and don't coalesce arthralgia arthritis Newborns deafness blindness CHD
43
Rubella diagnose and treat
direct culture rtPCR serology VACCINE LIVE ATTENUATED to prevent congenital syndrome
44
B19
ssDNA Grows in mitotic active cells Uses host
45
B19 symptoms
Slap cheek Fever Rash lacelike Aplastic chrisis: chronic anemia arthralgia arthritis hydrop fetalis
46
HHV 6/7
Enveloped dsDNA
47
HHV 6/7 workings
Prim infect by 3 | Replicates in T and B cells
48
HHV 6/7 signs
High fever 4 days Maculopapular rash follows 7 - t cell infect later than 6