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Viruses Flashcards

(61 cards)

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1
Q

SMEDI

A

Porcine parvovirus 1
Protoparvovirus
Parvoviridae family
small, non enveloped, negative sense DNA
capsid, 3 viral proteins: VP-1,2 (main neutralising antibodies),3
Uses cellular polymerase enzyme, so it will replicate in dividing cells

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2
Q

SMEDI biotypes

A

5 biotypes: 1. NADL-2: apathogenic, 2. Classical PPV-1: SMEDI, 3. Kresse strain: dermatitis, death of immunocompetent fetus, 4. Strain with skin symptoms, 5.Coinfections with PCV-2: PMWS, PRDC

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3
Q

Dog parvo

A

Canine Parvo Virus -2 (Pathogenic Serotype) Protoparvovirus
Parvoviridae family
CPV-1: original non pathogenic viruses of dogs
high resistance: month long survival → bleach disinfection!
In cats: in 10% feline panleukopenia is caused by CPV! (only A subtypes)

CPV2a, CPV2b, CPV2c

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4
Q

Feline panleukopenia / Feline distemper/ Feline parvo

A

Parvoviridae family
Carnivore Protoparvovirus (1)
FPLV- Feline Panleukopenia Virus

CPV-2a,b,c can also infect felidae

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5
Q

MEV

A

Mink enteritis disease virus (protoparvo, parvoviridae)
Patho, CS: like dog/ cat parvo
Vaccination: inactivated from 2 months of age, together with pseudomonas and botulism

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6
Q

ADV

A

Aleutian mink disease virus : parvovirus (amdoparvovirus)
ADV: aleutian mink disease virus (kills young animals as a result of massive humoral response to both the capsid and non-capsid viral proteins) Amdoparvovirus Parvoviridae
Aleutian genotype is more susceptible-defect in antigen presentation
young: intertitial pneumonia
older: hypergammaglobulinemia, glomerulonephritis
PLASMACYTOSIS
No virus neutralizing antibodies → Immuncomplexes → Type III hypersensitivity

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7
Q

Derzsy disease

A

Goose parvovirus , goose and muscovy duck are susceptible

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8
Q

Duck parvovirus- SBDS

A

Short beak and dwarfism syndrome
pathomechanism, dx, px like Derzsy
CS, patho different
only barbari and muscovy duck Geese isnt susceptible

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9
Q

PMWS

A

PCV-2, circovirus
post weaning multisystemic wasting syndrome

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10
Q

PDNS

A

porcine dermatitis nephropathy syndrome
PCV-2 but it may develop without PCV !!

high pcv ab titers –> type III hypersensitivity –> immunocomplex depositions in kidney, skin, blood vessels

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11
Q

PBFDV
PiCV
GoCV

A

PBFDV: psittaci beak and feather disease virus, young under 3 years
PiCV: pigeon Circovirus, 1-12 months
GoCV: goose circovirus, from 1week, coinfection with riemerella anatipestifer.

Immunosuppression, secondary bacterial infections
all circovirus genus, circoviridae family

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12
Q

CAV

A

chicken infectious anaemia
anelloviridae family, gyrovirus genus
it was a circovirus, but the replication cycle is a little bit different. First cell infected is the T progenitor cells and the myeloid progenitor cells.
Destroys red a white blood cells
anaemia and immunosuppression

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13
Q

Papillomatoses

A

papillomaviridae: linear dsDNA, non-enveloped, survives in the environment for months
Autovaccines are available
BoPV 1-6: bovine papillomatoses, delta (1,2), epsilon (5), xipapillomavirus (3,4,6)
1,2: infects horse, 1,2,3: skin lesions, 4: intestine 5,6: skin of udder. species specific immunity
EPV-2
Horse sarcoid: BoPV-1,2
dog, cat papillomatoses
human: >50 types

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14
Q

Horse sarcoid

A

BoPV 1,2

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15
Q

hemorrhagic nephritis and enteritis of geese

A

GHPV: goose hemorrhagic polyomavirus, polyomavirus genus, polyomaviridae
goose 4-10 w, muscovy duck (sero+, , symptomless, high titre)

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16
Q

pneumoenteritis of calves

A

1-4 months
Bovine mastadenovirus A-C, Bovine atadenovirus D-F
Hemorrhagic enteritis (C= BAdV-10)

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17
Q

pneumoenteritis of sheep

A

Ovine mastadenovirus A-c, Ovine atadenovirus D, bovine adenovirus

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18
Q

Rubarth disease/ infectious hepatitis

A

blue eye disease
dogs with vomiting, diarrhoea, bleeding, icterus
CAdV-1 Mastadenovirus, Adenoviridae
1-3 m
peracute/ acute/ extended
Type III hs, DIC–> IC depots
Cowdry A inclusion bodies

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19
Q

Infectious laryngotracheitis of dogs

A

CAdV-2

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20
Q

Inclusion body hepatitis

A

FAdV-1,7,8 Aviadenovirus

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21
Q

Hepatitis hydropericardium syndrome in goose

A

FAdV-4 Aviadenovirus

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22
Q

Turkey hemorrhagic encephalitis

A

TAdV-3 Siadenovirus

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23
Q

Marble spleen disease pheasant

A

TAdV-3 Siadenovirus

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24
Q

Splenomegaly in chicken

A

TAdV-3 Siadenovirus

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25
EDSV
DAdV-1 Atadenovirus
26
EDSV goose
DAdV-1 Atadenovirus
27
Alphaherpesvirinae
Alphaherpesvirinae subfamily - short replication (fast), latency in neural tissue Simplexvirus - BoHV-2 Varicellovirus - BoHV-1, -5 (IBR), EHV-1, 3-4, 8-9, SuHV-1 (Aujeszky), CaHV-1, FeHV-1 Mardivirus - GaHV-2, -3 (Marek 1, 2), MeHV-1 (turkey herpes 1) CoHV-1 Iltovirus - GaHV-1 (ILTV), PsHV-1 (Pacheco’s disease)
28
Betaherpesvirinae
Betaherpesvirinae subfamily - longer replication time, latency in diff. tissues, freq in salivary gl. Cytomegalovirus - HHV-5 Muromegalovirus - MCMV-1, -2 Proboscivirus - ElHV-1 (elephant herpes) Roseolovirus – HHV-6,-7 Unassigned - SuHV-2 (inclusion body rhinitis), CvHV-2, TuHV-1
29
Gammaherpesvirinae
Gammaherpesvirinae subfamily - quite long replication time, lymphoproliferating ➔ tumor Lymphocryptovirus - HHV-4, (Epstein-Barr virus) Rhadinovirus - BoHV-4 (Movar herpesvirus) Macavirus - OvHV-2 (malignant catarrh), AlHV-1, -2, BHV-6, SuHV-3, -4, -5 Percavirus - EHV-2, -5 Species unassigned to subfamilies and genera (several): AnHV-1 (duck plaque)
30
IBR
alphaherpesvirus, varicellovirus, BoHV-1(5)
31
Bovine Herpes Mammilitis
BoHV-2, simplexvirus, alphaherpes
32
Inclusion body rhinitis , swine
SuHV-2 , unassigned, betaherpesvirus
33
Malignant catarrhal fever
Gammaherpes,Macavirus: AlHV-1, OvHV-2 cattle gets it from sheep, they are asymptomatic cattle does not infect other cattle fast spread tho no vax no tx
34
Aujeszky
alphaherpes, varicellovirus: SuHV-1 all mammals except humans, die too fast to shed pigs- all ages Mad itch- cattle, goat, sheep
35
Equine rhinopneumonitis/ epizootic abortion
EHV-1 : respiratory signs, abortion, CNS signs EHV-4: respiratory signs, (abortion) 75% DNA homology--> cross-reaction, but no cross-protection! abortion storms-30-40%, sudden vaccines are available: usually protect against respiratory forms
36
EHV-2,3,5
EHV-2: percavirus, gammaherpes, respiratory signs, only in young horses, can be isolated from many healthy horses, so the role is unknown EHV-3: coital exanthema, varicellovirus, alphavirus. benign venereal disease. NO abortion NO foethopathy EHV-5: percavirus, gammaherpes , role in EMPF: equine multinodular pulmonary fibrosis, but unknown exactly
37
Infectious rhinotracheitis in cat
FeHV-1, varicellovirus, alphaherpes, YOPI, adult: abortion >10 w most susceptible >1 y rarely
38
Canine herpes
CaHV-1, varicellovirus, alphaherpes all ages <3 w most susceptible, abortion in pregnant bitches (vax)
39
infectious laryngotracheitis of chickens (ILT)
GaHV-1 , iltovirus genus, alphaherpesvirinae no viraemia, no germinative infection mainly growers, adults >8-10 weeks very contagious, fast spread
40
Marek disease
GaHV-2,3 Mardivirus genus, Alphaherpesvirinae two serotypes: 1. marek disease : very virulent/virulent/low virulence/avirulent 2. apathogenic, + MeHV-1 --> vaccine strain 1-2 most suceptible neural form, visceral form tumour formation acute > 6 w, chronic >6 mo virus shedding through feather follicles no germinative infection diff.dx. reticuloendotheliosis -- diff only by lab!
41
Duck plaque
AnHV-1 unassigned, gammaherpes? duck, goose, swan- adults are more susceptible "duck viral enteritis" vax
42
Pigeon herpes
CoHV-1, Mardivirus genus, Alphaherpesvirinae mainly 2-6 months adults are asymptomatic carriers vax
43
Cowpox
orthopox genus, chordopoxvirinae zoonotic hemorrhagic lesions aka black spots
44
Pseudocowpox
no black spots as in cowpox parapox, chordopoxvirinae no lifelong immunity, coz it is parapox zoonotic Milker's nodule
45
Bovine pustular dermatitis
parapox, chordopoxvirinae no lifelong immunity coz it is parapox mouth and the skin around is affected only cattle, 1-6 m adult: carriers
46
Lumpy skin disease
notifiable, not in Europe capripox, chordopoxvirinae mechanical vector: mosquito wet season: generalised form, frequent dry season: localised form, mild
47
Contagious pustular dermatitis of sheep and goat ORF, ectyma contagiosa
Parapox notifiable zoonotic--> use gloves!
48
Swine pox
suipox
49
Sheep and goat pox
capripox two different viruses, both infect both sheep and goat eradicated from europe, Us, Aus widely distributed in Asia and Africa lymphoma like nodules in lungs, GIT, crosses fetus
50
Myxomatosis
notifiable leporipox hares arent susceptible but cotton tailed rabbits and domestic rabbit are mosquitoes! 2 types: south american and californian (higher V) forms typical nodular atypical
51
Fowl pox
Avipox
52
ASF
asfivirus g, asfarviridae, linear dsDNA hemorrhages everywhere, all ages, always abortus soft ticks! no vax
53
Porcine polioencephalomyelitis Teschen, Talfan
Teschovirus , porcine enterovirus I, picornavirales, picornaviridae Teschen: high V, all ages Talfan: low V, <4 m , mostly 5-8 w Po--> GI epithelium. Enteric phase.no CS, shedding 6-8 w--> recovery OR enters bloodstream --> viraemic phase--> CNS --> neural phase
54
Swine vesicular disease
picornaviridae , enterovirus serotype 9 vesicles from coxaci b5
55
Vesicular exanthema of swine
from sea mammals calicivirus, vesivirus
56
Avian encephalomyelitis
Tremovirus, picornaviridae all ages germinative infection: infected birds lay infected eggs, it does not kill embryo
57
Duck hepatitis
Type I Picornaviridae, Avihepatovirus, Duck hepatitis A virus Everywhere, clinically up to 6 weeks of age, highest virulence Incubation: 18-48 hours, every death within 1 week, up to 95% Type II Astroviridae, Avastrovirus, Duck astrovirus (+ssRNA, nonenveloped) UK, Up to 6 weeks of age Difficult to isolate, propagate’ Type III Picornaviridae, unassigned picornavirus 30% mortality Duck hepatitis B Hepadnaviridae, Avihepadnav, Duck hepatitis B (circ, dsDNA, envelope) China, older ducks and geese
58
Encephalomyocarditis
cardiovirus, picornaviridae rodents, swine, captive zoo animals, eg elephant
59
FMD
aphtovirus, picornaviridae cattle > swine> sheep , goat notifiable, human can be infected europe is currently free vaccination: only endemic areas stamping out policy shedding from 9hpi O, A, C, Sat 1,2,3, Asia 1
60
TGE
Porcine Transmissible Gastroenteritis Virus (TGEV) Alphacoronavirus 1a Coronaviridae +ssRNA, enveloped
61
Anthrax
Bacillus anthracis

Epidemiology (2 decks)

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