VIRUSES Flashcards

(44 cards)

1
Q

a small amount of DNA surrounded by a
protein envelope

A

virus

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2
Q

a retrovirus that attacks the immune system and is
the causative agent of AIDS

A

human immunodeficiency virus (HIV

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3
Q

a disease caused by the human immunodeficiency
virus, which is characterized by low T cell counts
leading to infections that often prove fatal

A

acquired immunodeficiency syndrome (AIDS)

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4
Q

a complete virus particle consisting of
nucleic acid and coat protein

A

virion

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5
Q

the protein coat of a virus

A

capsid

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6
Q

s a small amount of genetic material surrounded by
a protein envelope

A

Virus

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7
Q

They are pathogens
of

A

bacteria, plants, and animals.

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8
Q

The classic viral shape most
often seen in the literature has

A

hexagonal capsid, rod sticking

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9
Q

a method for treating a genetic
disease by introducing a good copy of a defective
gene

A

gene therapy

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10
Q

a genetic disease that affects DNA synthesis in the
cells of the immune system

A

severe combined immune deficiency (SCID)

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11
Q

a vector
commonly used in gene therapy

A

Maloney murine leukemia virus (MMLV)

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12
Q

in gene therapy, the
assemblage that contains the gene being
transferred

A

expression cassette

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13
Q

a simple DNA virus that is often used
for gene therapy

A

adenovirus

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14
Q

the proteins that make up the
capsid or protein coat that surrounds the genetic
material of a virus

A

coat proteins (CP)

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15
Q

the enzyme that
directs the synthesis of DNA on an RNA template

A

reverse transcriptase (RT)

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16
Q

proteins found in the
outer membrane of a virus

A

envelope proteins (EP

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17
Q

a disease in which
the immune system attacks the body’s
own tissues

A

Auto immune disease

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18
Q

a weakened or killed form of an infectious agent that is injected into an organism so that it will
make antibodies against the true infectious agent

19
Q

white blood cells that play an important
role in the functioning of the immune system

20
Q

the first line of defense in the
immune system

A

innate immunity

21
Q

innate immunity cells that are the
first to encounter viruses or bacteria

A

dendritic cells

22
Q

cells of the innate immune system
that digest cellular debris and pathogens

23
Q

cells of the innate
immune system that kill cells which have been
infected or are cancerous

A

natural killer (NK) cells

24
Q

protein that displays an antigen on the surface of
cells of the immune system

A

major histocompatibility complex (MHC)

25
components of the human immune system; the target of the AIDS virus
helper T cells (TH cells
26
cells of the immune system that display antigens on their surface and activate the acquired immunity system
antigen-presenting cells (APCs
27
soluble protein factors produced by one cell that affect another cell
cytokines
28
components of the human immune system
killer T cells
29
white blood cells that play an important role in the immune system and play a role in the production of antibodies
b cells
30
a type of white blood cell; a major component of the immune system
lymphocytes
31
one of two kinds of white blood cells important in the immune system—a killer T cell, which destroys infected cells, or a helper T cell, which is involved in the process of B-cell maturation
T cells
32
Where t cells mainly found?
thymus gland
33
Where b cells mainly found?
Bone marrow
34
substances that trigger an immune response
Antigens
35
proteins that play a role in the immune system
interleukins
36
the process by which the immune system responds selectively to antibodies actually present in an organism
clonal selection
37
(immunoglobulins) glycoproteins that bind to and immobilize a substance that the cell recognizes as foreign
antibodies
38
binding sites for antibodies on an antigen
epitopes
39
a kind of cell produced by fusing lymphocytes and mouse myeloma cells
hybridoma
40
antibodies produced from the progeny of a single cell and specific for a single antigen
monoclonal antibodies
41
the spread of cancer throughout the body
metastasis.
42
a gene that encodes a protein that inhibits cell division
tumor suppressor
43
the first virus to be shown to cause cance
Rous sarcoma virus
43
normal eukaryotic genes that are very similar in sequence to a cancer causing gene
proto-oncogenes