Viruses And prions

Question 1

What is a DNA virus that is enveloped

Answer 1

Herpes Simplex Virus

Question 2

HSV-1 prefers to be in the?

Answer 2

Oral mucosa

Question 3

HSV-1 causes

Answer 3

Oral herpes

genital herpes

Question 4

HSV-1 transmission

Answer 4

Oral secretions

Question 5

HSV-1 Pathogenesis

Answer 5

• Infects cells around site of entry (oral mucosa)
• Remains latent in trigeminal nerve ganglia
• Can travel back to oral mucosa —>active infection

Question 6

HSV-1 activation is associated with :

Answer 6

UV light
Emotional Stress
Mensuration

Question 7

Oral herpes Signs/symptoms

Answer 7

Cold sores: painful, short-lived vesicles on outer margin of lips

Question 8

Oral herpes DX

Answer 8

Clinical assessment

Nucleic acid infection

Question 9

Oral herpes Tx

Answer 9

Acyclovir & Valacyclovir

Question 10

HSV-2 prefers to be in ?

Answer 10

Genital mucosa

Question 11

HSV-2 causes

Answer 11

Genital herpes

Oral herpes

Question 12

HSV-2 transmission

Answer 12

Sexual conduct

Question 13

HSV-2 Pathogenesis

Answer 13

• Infects cells around site of entry (genital mucosa)
• Remains latent in sacral nerve ganglia
• Can travel back to genital mucosa —> active infection

Question 14

HSV-2 activation Is associated with ?

Answer 14

Emotional distress

Menstruation

Question 15

Genital Herpes Signs/symptoms

Answer 15

Vesicles on genitals

Burning during urination

Question 16

Genital herpes DX

Answer 16

Clinical assessment

Nucleic acid identification

Question 17

Genital herpes Tx

Answer 17

Acyclovir

Valacyclovir

Question 18

RNA virus that is enveloped

Answer 18

Rabies virus

Question 19

Rabies virus causes ?

Answer 19

Rabies

Question 20

Rabies virus transmission

Answer 20

Saliva from bite of infected animal

Question 21

Rabies virus most common reservoirs ?

Answer 21

Raccoons, skunks, bats

Question 22

Rabies pathogenesis

Answer 22

-Rabies virus injected into body —> enter
muscle cells and replicate
-Rabies virus enters motor neuron and
travels to CNS —>brain
-Rabies virus can travel to salivary glands
and other organs

Question 23

Rabies signs/symptoms

Answer 23

Tingling around bit, muscle spasms, weakness, fever

Question 24

What are the two forms of clinical rabies

Answer 24

Furious rabies

Paralytic rabies

Question 25

Genital Warts signs/symptoms

Answer 25

Bumps of genitals

Question 26

Genital warts DX

Answer 26

Clinical assessment | Nucleic acid identification

Question 27

Genital warts Tx

Answer 27

Gels for warts (not antivirals)

Question 28

Human papilloma virus Pathogen

Answer 28

Infects epithelial cells

Question 29

HOV-6 and HPV-11

Answer 29

DNA remains extra chromosomal | Infected cells increase keratin production

Question 30

HPV-16 and HPV-18

Answer 30

DNA integrates into host cell’s chromosome | HPV-16 and -18 DNA encode proteins that suppress host cell tumor suppressor proteins

Question 31

Human Papillomavirus (HPV)

Answer 31

Over 200 types DNA viruses Non-enveloped

Question 32

HPV cause genital warts | Most common?

Answer 32

HPV-6 & HPV-11

Question 33

HPV Can cause cancer | Most common ?

Answer 33

HPV-16 & HPV-18

Question 34

HPV transmission

Answer 34

Sexual contact

Question 35

Some virus contains oncogenes that means ?

Answer 35

Oncogenic viruses

Question 36

Oncogenic virus :

Answer 36

Human papilloma virus

Question 37

Cancer is caused by

Answer 37

Mutagens Viruses Inherited

Question 38

Oncogene

Answer 38

gene with ability to convert normal cell to | cancer cell

Question 39

Cancer

Answer 39

Abnormal cells divide uncontrollably

Question 40

Rabies Dx

Answer 40

Nucleic acid identification | Negri bodies in cytoplasm of nerve cells

Question 41

Rabies Tx

Answer 41

start ASAP after bite from infected animal) - Rabies vaccine + immune globulin injections - Once clinical rabies signs/symptoms appear, treatment is usually ineffective

Question 42

Paralytic rabies signs/symptoms

Answer 42

Muscle paralysis Viral encephalitis Coma

Question 43

Furious Rabies signs/symptoms

Answer 43

Hydrophobia Excessive salivation Aggression Viral encephalitis