Vitamin A (Retinol) Flashcards

1
Q

Vitamin A is a ____ carbon lipid molecule obtained in the diet either directly or indirectly from ______________

A

20/B-cartoene

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2
Q

when b carotene is cleaved what forms

A

vitamin A1(retinol)

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3
Q

when the oxidation of alcohol to aldehyde of vitamin a1 (retinol) forms:

A

11-cis-retinal (visual pigment)

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4
Q

when 11-cis retinal is exposed to visible light it forms

A

all trans retinal which is a neual signal to brain

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5
Q

when the aldehyde of 11 cis retinal is oxidized to acid it forms?

A

retonic acid which is a hormal signal epithelial cells

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6
Q

what is the function of retinoic acid?

A

is a singal compound that binds to receptor proteins inside the cells,
the ligand-receptor complexes binds then to chromosomes and regulate gene expression during cell differentiation

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7
Q

what is the function of retinal

A

light senstive compound (As said earler) so important in vision
retinal is a prosthetic group of the protein rhodopsin
absorption of photon of light by retinal triggers a neural impulse

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7
Q

what are dietary sources of vitamin A?

A

1 oily fish
2 liver
3 eggs
4 whole milk
5 butter

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8
Q

what are dietary sources of b carotene

A

1 carrots
2 sweet potatoes
3 yellow vegtables

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9
Q

what happens in the defeciency of vitamin a

A

1 dryness of the skin, eyes and mucous membranes
2 retarted development and growth
3 night blindness
4 tendencay to form inflammation

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10
Q

Toxicity primarily affects central nervous system and results in ________, ___________, _________, ____________.

A

ataxia, anorexia,sickness, headache

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11
Q

what is heptamegalia?

A

histological changes in the liver

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12
Q

what is hyperlipidemia?

A

thickness in long bones

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13
Q

what is hypercalcemia?

A

dryness in skin

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14
Q

what happens when a pregnant uses lots of vitamin A

A

affects the fetus development and cause malformations

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