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BIOCHEMISTRY > Vitamins, RBC, COFACTORS, WBC > Flashcards

Vitamins, RBC, COFACTORS, WBC Flashcards

1
Q

Nicotinic acid

A

LIVER

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2
Q

Vit D plants

A

Ergocalciferol

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3
Q

CORN

A

Niacin

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4
Q

GPIa-IIa

A

Integrin

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5
Q

VwF

A

alpha granules

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6
Q

Laki-lorand

A

fibrinase

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7
Q

Greatest amount of plasma

A

Factor 1

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8
Q

Long half-life

A

factor XIII

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9
Q

Shortest half-life

A

Thromboxane A2

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10
Q

Hemolytic anemia

A

G6PD

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11
Q

Hereditary spherocytosis-

A

spectrin

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12
Q

Double-helical filaments of f-actin

A

Actin (band 5)

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13
Q

Immunodominant sugar for blood type A

A

GalNac transferase

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14
Q

can cause recurrent infections

A

Myeloperoxidase

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15
Q

respiratory burst, chronic granulomatous disease

A

NADPH oxidase

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16
Q

Beta chain changed from GAG to GTG

A

Sickle cell anemia

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17
Q

Conversion of 1,3-BPG to 2,3-BPG

A

2,3BPG mutase

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18
Q

RBCs generate ATP through –

A

GLYCOLYSIS

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19
Q

Ingest by endocytosis, present antigen on surface

A

Helper T cells

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20
Q

Recognize proteins that appear on host cells as a consequence of viral infection –

A

– Cytotoxic T cells

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21
Q

Activation of cytotostolic phospholipase A2

A

Arachidonic acid

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22
Q

Vit. that can cause lactic acidosis

A

Thiamine

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23
Q

Vit. that prevents oxidation of PUFA

A

Vit. E

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24
Q

Folate trap

A

Deficiency in Vit. B12

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25
Q

Toxicity of Niacin affects:

A

LIVER

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26
Q

Promotes transfer of Ca from bone to blood:

A

1,25-diOH-D3

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27
Q

Def of Vit. E

A

Hemolytic anemia

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28
Q

Fletcher factor

A

Prekallikrein

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29
Q

Deficiency of Riboflavin-

A

CHEILOSIS

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30
Q

Pellagra

A

Dementia

31
Q

carcinoid syndrome

A

Niacin

32
Q

Scurvy except:

A

demineralization

33
Q

deficiency found in vegetarians

A

Cobalamin

34
Q

Transporter chu for RBC

A

GLUT1

35
Q

Hemoglobin from methemoglobin:

A

CYTOCHROME B5 REDUCTASE (aka methmoglobin reductase)

36
Q

Deficiencies in amount of structure of alpha- or beta-spectrin, ankyrin, band 3, or band 4.1:

A

HEREDITARY SPHEROCYTOSIS

37
Q

NADPH oxidase deficiency

A

CGD:

38
Q

Polymerization of fibrin clot:

A

PEPTIDE BOND

39
Q

Fibrinogen do not aggregate because of:

A

Negative charge due to high aspartate, glutamate residues

40
Q

Serves as a receptor on platelet surface for factor IXa and X:

A

FACTOR VIII

41
Q

2nd most common enzyme deficiency asso. with Hemolytic anemia:

A

PYRUVATE KINASE

42
Q

Binding of GPIb-IX-V is mediated via:

A

von Willebrand Factor (vWF)

43
Q

Ingest and present antigens from phagocytes:

A

T helper cell

44
Q

Viral and malignant(? or neoplastic?? smth) transformations:

A

T cytotoxic cell

45
Q

Xerophthalmia can be manifested as

A

dry conjuntiva

46
Q

Avidin in egg

A

Biotin deficiency

47
Q

Prolonged antibiotic affects need administration of?

A

Vit. K

48
Q

Vitamin K is required for synthesis of

A

prothrombin

49
Q

First to arrive at site of inflammation

A

Neutrophil

50
Q

All phagocytize except

A

Lymphocyte

51
Q

Results in increase of eosinophils

A

allergy and parasitic infection

52
Q

Not a symptom of scurvy

A

bone demineralization

53
Q

Symptom of vit D toxicity

A

weakness

54
Q

Largest and forms into a macrophage-

A

monocytes

55
Q

Retinol esters are hydrolyzed in the

A

intestinal mucosa

56
Q

Riboflavin coenzymes are electron carriers in the ff reactions except –

A

Glycolysis

57
Q

Required daily folic acid intake for pregnant women

A

0.4mg

58
Q

Vit D RDA

A

200 IU

59
Q

Vit A intake in adults

A

greater than 1000 IU

60
Q

Vit E deficiency in premature infants

A

hemolytic anemia

61
Q

Associates with dry skin and paralysis

A

Beri-beri

62
Q

Vit B12 deficiency

A

Folate trap

63
Q

Dihydroxyfolate reductase

A

Trimethoprim (or methotrexate)

64
Q

Ergocalciferol

A

plants vit D

65
Q

Pruritic skin-

A

vit A

66
Q

Enzyme converting Homocysteine to methionine:

A

methyl transferase

67
Q

cephalosporin medication

A

Vit. K

68
Q

Lactic acidosis –

A

thiamin

69
Q

Deamination/ transamination reactions-

A

pyridoxine (b6)

70
Q

Forms carboxyglutamate:

A

vit K

71
Q

Liquid part of blood

A

plasma

72
Q

Rh- mother, Rh+ baby

A

Erythroblastosis fetalis

73
Q

Precursor to all blood cells-

A

hemocytoblast

74
Q

neither anti a or b antibodies, a and b antigens (what blood type)

A

AB blood type

BIOCHEMISTRY (5 decks)

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