Vocab #2 Flashcards

(54 cards)

1
Q

Catabolic pathway

A

A metabolic pathway that releases energy by breaking down complex molecules to simpler molecules

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2
Q

Anabolic pathway

A

A metabolic pathway that consumes energy to synthesize a complex molecule from simpler molecules

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3
Q

Oxidation

A

The complete or partial loss of electrons from a substance involved in a redox reaction

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4
Q

Reduction

A

The complete or partial addition of electrons to a substance involved in a redox reaction

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5
Q

Exergonic

A

A spontaneous chemical reaction, in which there is a net release of free energy

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6
Q

Endergonic

A

A non spontaneous chemical reaction, in which free energy is absorbed from the surroundings

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7
Q

ATP

A

An adenine-containing nucleotide triphosphate that releases free energy when its phosphate bonds are hydrolyzed. This energy is used to drive endergonic reactions in cells.

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8
Q

Catalyst

A

A chemical agent that selectively increases the rate of a reaction without being consumed by the reaction.

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9
Q

Enzyme

A

A macromolecule serving as a catalyst, a chemical agent that increases the rate of a reaction without being consumed by the reaction. Most are proteins.

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10
Q

Activation Energy

A

The amount of energy that reactants must absorb before a chemical reaction will start; also called free energy of activation

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11
Q

Substrate

A

The reactant on which an enzyme works

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12
Q

Active Site

A

The specific region of an enzyme that binds the substrate and that forms the pocket in which catalysis occurs

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13
Q

Competitive inhibitor

A

A substance that reduces the activity of an enzyme by entering the active site in place of the substrate, whose structure it mimics.

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14
Q

Noncompetitive inhibitor

A

A substance that reduces the activity of an enzyme by binding to a location remote from the active site, changing the enzyme’s shape so that the active site no longer effectively catalyzes the conversion of substrate to product

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15
Q

Allosteric regulation

A

The binding of a regulatory molecule to a protein at one site that affects the function of the protein at a different site

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16
Q

Feedback inhibition

A

A method of metabolic control in which the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway

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17
Q

Cellular respiration

A

The catabolic pathways of aerobic and anaerobic respiration, which break down organic molecules and use an electron transport chain for the production of ATP

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18
Q

Photosynthesis

A

The conversion of light energy to chemical energy that is stored in sugars or other organic compounds; occurs in plants, algae, and certain prokaryotes

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19
Q

Chemiosmosis

A

An energy-coupling mechanism that uses energy stored in the form of a hydrogen ion gradient across a membrane to drive cellular work, such as the synthesis of ATP. Under aerobic conditions, most ATP synthesis in cells occurs by this process

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20
Q

Citric acid cycle (krebs cycle)

A

A chemical cycle involving eight steps that completes the metabolic breakdown of glucose molecules begun in glycolysis by oxidizing acetyl CoA (derived from pyruvate) to carbon dioxide; occurs within the mitochondrion in eukaryotic cells and in the cytosol of prokaryotes; together with pyruvate oxidation, the second major stage in cellular respiration

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21
Q

Glycolysis

A

A series of reactions that ultimately splits glucose into pyruvate. It occurs in almost all living cells, serving as the starting point for fermentation or cellular respiration.

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22
Q

Substrate-level

A

The enzyme-catalyzed formation of ATP by direct transfer of a phosphate group to ADP from an intermediate substrate in catabolism.

23
Q

Phosphorylation

A

The process of generating ATP from ADP and phosphate by means of chemiosmosis, using a proton-motive force generated across the thylakoid membrane of the chloroplast or the membrane of certain prokaryotes during the light reactions of photosynthesis.

24
Q

Oxidative phosphorylation

A

The production of ATP using energy derived from the redox reactions of an electron transport chain; the third major stage of cellular respiration.

25
Electron transport chain
A sequence of electron carrier molecules (membrane proteins) that shuttle electrons down a series of redox reactions that release energy used to make ATP.
26
Mitochondrion
An organelle in eukaryotic cells that serves as the site of cellular respiration; uses oxygen to break down organic molecules and synthesize ATP.
27
Aerobic
A catabolic pathway for organic molecules, using oxygen (O2) as the final electron acceptor in an electron transport chain and ultimately producing ATP. This is the most efficient catabolic pathway and is carried out in most eukaryotic cells and many prokaryotic organisms.
28
Anaerobic
A catabolic pathway in which inorganic molecules other than oxygen accept electrons at the "downhill" end of electron transport chains.
29
Light reactions
The first of two major stages in photosynthesis (preceding the Calvin cycle). These reactions, which occur on the thylakoid membranes of the chloroplast or on membranes of certain prokaryotes, convert solar energy to the chemical energy of ATP and NADPH, releasing oxygen in the process.
30
Calvin cycle
The second of two major stages in photosynthesis (following the light reactions), involving fixation of atmospheric CO2 and reduction of the fixed carbon into carbohydrate.
31
Chlorophyll
A green pigment located in membranes within the chloroplasts of plants and algae and in the membranes of certain prokaryotes. Type a participates directly in the light reactions, which convert solar energy to chemical energy.
32
Chloroplast
An organelle found in plants and photosynthetic protists that absorbs sunlight and uses it to drive the synthesis of organic compounds from carbon dioxide and water.
33
Stomata (stoma, singular)
A microscopic pore surrounded by guard cells in the epidermis of leaves and stems that allows gas exchange between the environment and the interior of the plant.
34
Signal transduction pathway
The linkage of a mechanical, chemical, or electromagnetic stimulus to a specific cellular response.
35
Positive feedback
A form of regulation in which an end product of a process speeds up that process; in physiology, a control mechanism in which a change in a variable triggers a response that reinforces or amplifies the change.
36
Negative feedback
A form of regulation in which accumulation of an end product of a process slows the process; in physiology, a primary mechanism of homeostasis, whereby a change in a variable triggers a response that counteracts the initial change.
37
Chromosome
A cellular structure carrying genetic material, found in the nucleus of eukaryotic cells. Each consists of one very long DNA molecule and associated proteins. (In bacteria, they usually consist of a single circular DNA molecule and associated proteins. They are found in the nucleoid region, which is not membrane bounded.)
38
Mitosis
A process of nuclear division in eukaryotic cells conventionally divided into five stages: prophase, prometaphase, metaphase, anaphase, and telophase. It conserves chromosome number by allocating replicated chromosomes equally to each of the daughter nuclei.
39
Cytokinesis
The division of the cytoplasm to form two separate daughter cells immediately after mitosis, meiosis I, or meiosis II.
40
Sister chromatids
Two copies of a duplicated chromosome attached to each other by proteins at the centromere and, sometimes, along the arms. While joined, two sister chromatids make up one chromosome. Chromatids are eventually separated during mitosis or meiosis II.
41
Interphase
The period in the cell cycle when the cell is not dividing. During this phase, cellular metabolic activity is high, chromosomes and organelles are duplicated, and cell size may increase. It often accounts for about 90% of the cell cycle.
42
G0 phase
A nondividing state occupied by cells that have left the cell cycle, sometimes reversibly.
43
G1 phase
The first gap, or growth phase, of the cell cycle, consisting of the portion of interphase before DNA synthesis begins.
44
G2 phase
The second gap, or growth phase, of the cell cycle, consisting of the portion of interphase after DNA synthesis occurs.
45
S phase
The synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated.
46
Checkpoint
A control point in the cell cycle where stop and go-ahead signals can regulate the cycle.
47
Cyclin
A cellular protein that occurs in a cyclically fluctuating concentration and that plays an important role in regulating the cell cycle.
48
Cyclin-dependent kinase
A protein kinase that is active only when attached to a particular cyclin.G
49
Growth factor
(1) A protein that must be present in the extracellular environment (culture medium or animal body) for the growth and normal development of certain types of cells. (2) A local regulator that acts on nearby cells to stimulate cell proliferation and differentiation.
50
Density-dependent inhibition
The phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another.
51
Anchorage dependence
The requirement that a cell must be attached to a substratum in order to initiate cell division.
52
Tumor
A gene whose protein product inhibits cell division, thereby preventing the uncontrolled cell growth that contributes to cancer.
53
Metastasis
The spread of cancer cells to locations distant from their original site.
54
Mutation
A change in the nucleotide sequence of an organism's DNA or in the DNA or RNA of a virus.