Vocab for Body Systems Flashcards

(431 cards)

1
Q

Drugs

A

Medicines/Substances used to prevent or treat a condition or disease

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2
Q

L.A.D.M.E.

A

Liberation
Absorption
Distribution
Metabolism
Excretion

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3
Q

Addiction

A

Physical & Psychological dependence on and craving for a drug

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4
Q

Additive Action

A

Drug action in which the combination of two similar drugs is equal to the sum of the effects of each

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5
Q

Aerosol

A

Particles of drug suspended in air

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6
Q

Anaphylaxis

A

Exaggerated hypersensitivity reaction to a previously encountered drug or foreign protein

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7
Q

Antagonistic Action

A

Combination of two drugs give less than an additive effect

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8
Q

Antidote

A

Agent given to counteract an unwanted effect of a drug

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9
Q

Brand Name

A

Commercial name for a drug
Trademark or Trade name

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10
Q

Chemical Name

A

Chemical formula for a drug

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11
Q

Generic Name

A

Legal noncommercial name for a drug

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12
Q

Contraindications

A

Factors that prevent the use of a drug or treatment

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13
Q

Controlled Substances

A

Drugs that produce tolerance and dependence that have potential for abuse or addiction

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14
Q

Dependence

A

Prolonged use of a drug that may lead to a physiologic need for its actions in the body

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15
Q

Dose

A

Amount of drug administered

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16
Q

FDA

A

Food & Drug Administration
US Government agency with legal responsibility to enforce proper drug manufacture and clinical use

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17
Q

Iatrogenic

A

Condition caused by treatment given by physicians or medical personnel

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18
Q

Idiosyncratic Reaction

A

Unexpected effect produced in a particularly sensitive patient, but not seen in most people

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19
Q

Medicinal Chemistry

A

Study of new drug synthesis
Relationship between chemical structure & biological effects

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20
Q

Molecular Pharmacology

A

Study of interaction of drugs and their target molecules

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21
Q

Oral Administration

A

Drugs are given by mouth

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22
Q

Sublingual Administration

A

Drugs are given by placement under the tongue
SL

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23
Q

Rectal Administration

A

Drugs are inserted through the anus into the rectum

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24
Q

Inhalation

A

Administration of drugs in gaseous or vapor form through the nose or mouth

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25
Topical Application
Drugs are applied locally on the skin or mucous membranes of the body
26
Parenteral Administration
Drugs are given by injection into the skin, muscles or veins Intracavitary; Intradermal; Intramuscular (IM); Intrathecal; Intravenous (IV); Subcutaneous (SC) or (SQ) or (subQ)
27
Pharmacist
Pharmacology Professional - PharmD Specialist in preparing and dispensing drugs
28
Pharmacy
Location for preparing and dispensing drugs The study of preparing and dispensing drugs
29
Pharmacologist
Pharmacology Professional - MD or PhD Specialist in the study of properties, uses, and side effects of drugs
30
Pharmacodynamics
Study of a drug's effects in the body
31
Pharmacokinetics
Study of a drug's absorption, distribution into body compartments, metabolism, and excretion over a period of time
32
Pharmacology
Study of the preparation, properties, uses, and side effects of drugs
33
PDR
Physician's Desk Reference Reference book that lists drug products
34
Receptor
Target substance with which a drug interacts in the body
35
Resistance
Lack of beneficial response
36
Response
Desired and beneficial effect of a drug
37
Schedule
Exact timing and frequency of drug administration
38
Side Effect
Adverse reaction, usually minor that routinely results from use of a drug
39
Synergism
Combination of two drugs causes an effect that is greater than the sum of the individual effects of each drug alone
40
Syringe
Instrument for introducing or withdrawing fluids from the body
41
Tolerance
Larger and larger drug doses must be given to achieve the desired effect
42
Toxicity
Harmful effects of a drug
43
Toxicology
Study of harmful chemicals and their effects on the body
44
Transport
Movement of a drug across a cell membrane into body cells
45
USP
United States Pharmacopeia Authoritative list of drugs, formulas, and preparations that sets a standard for drug manufacturing and dispensing
46
Vitamin
Substance found in foods and essential in small quantities for growth and good health
47
A.C. or AC
Before meals
48
ACE
Angiotensin-converting enzyme
49
Ad-lib
Freely; As desired
50
APAP
Acetaminophen
51
ARB
Angiotensin II Receptor Blocker
52
B.I.D. or BID
Two times a day
53
C-
With
54
Caps
Capsules
55
CC
Cubic Centimeter
56
GM or G
Gram
57
GTT
Drops
58
H
Hour
59
H.S. or HS
At bedtime
60
H2 Blocker
Histamine h2 receptor antagonist
61
HRT
Hormone Replacement Therapy
62
INH
Isoniazid-antituberculosis agent
63
MAOI
Monoamine oxidase inhibitor
64
MG
Milligram
65
ML
Milliliter
66
NPO
Nothing by mouth
67
NSAID
Non-steroidal anti-inflammatory drug
68
P-
After
69
P.C. or PC
After Meals
70
PCA
Patient controlled analgesia
71
P.O. or PO
By Mouth
72
P.R.N. or PRN
As needed; as necessary
73
PT
Patient
74
Q
Every
75
Q.H. or QH
Every hour
76
Q2H
Every 2 hours
77
Q.I.D. or QID
Four times a day
78
Q.S. or QS
Sufficient quantity
79
QAM
Every morning
80
QPM
Every evening
81
RX
Prescription
82
S-
Without
83
SERM
Selective estrogen receptor modulator
84
SIG.
Directions - how to take medication
85
S.O.S.
If it is necessary
86
SSRI
Selective serotonin reuptake inhibitor
87
TAB
Tablet
88
TCA
Tricyclic antidepressant
89
T.I.D. or TID
Three times daily
90
Angiotensin Converting Enzyme (ACE) Inhibitor
Lowers blood pressure by dilating blood vessels. Block the conversion of angiotensin I to angiotensin II (a powerful vasoconstrictor).
91
Amphetamine Caffeine
Central nervous system stimulant
92
Analgesic
Relieves pain
93
Androgen
Male hormone
94
Anesthetic
Reduces or eliminates sensation; general and local
95
Angiotensin II Receptor Blocker
Lowers blood pressure by preventing angiotensin from acting on receptors in blood vessels
96
Antacid
Neutralizes acid in the stomach
97
Antiandrogen
Blocks formation of androgens or interferes with their effect in tissues
98
antiarrhythmic
Treats abnormal heart rhythms
99
Antibiotic
Chemical substance, produced by a plant or microorganism, that has the ability to inhibit or destroy foreign organisms in the body
100
Anticoagulant
Prevents blood clotting
101
Anticonvulsant
Prevents convulsions (abnormal brain activity)
102
Antidepressant
Relieves symptoms of depression
103
Antidiabetic
Given to prevent or treat diabetes mellitus
104
Antidiarrheal
Prevents diarrhea
105
Antiemetic Antinauseant
Prevents or relieves nausea and vomiting
106
Antihistamine
Blocks the action of histamine and helps prevent symptoms of allergy
107
Antimicrobial
Agent that kills microorganisms or stops their growth
108
Antiplatelet
Reduces the tendency of platelets to stick together and form a clot
109
Antiulcer
Inhibits the secretion of acid by cells lining the stomach
110
Antiviral
Acts against viruses such as herpes viruses and HIV
111
Aromatase Inhibitor
Reduces estrogen in the blood by blocking the enzyme aromatase
112
Beta Blocker Beta-Blocker
Blocks the action of epinephrine at sites on receptors of heart muscle cells, the muscle lining of blood vessels, and bronchial tubes; antiarrhythmic, antianginal, and antihypertensive.
113
Bisphosphonate
Prevents bone loss in osteoporosis
114
Calcium Channel Blocker Calcium Antagonist
Blocks the entrance of calcium into the heart muscle and muscle lining of blood vessels; used as an antiarrhythmic, antianginal, and antihypertensive;
115
Cardiac Glycoside
Drug that treats heart failure by increasing the force of contraction of the heart -Digoxin is an example
116
Cardiovascular Drug
Acts on the heart and blood vessels. Includes ACE Inhibitors, Beta Blockers, Calcium Channel Blockers, Statins, and Diuretics
117
Cathartic
Relieves constipation
118
Cholesterol-Binding Drug
Binds to dietary cholesterol and prevents its uptake from the gastrointestinal tract
119
Cholesterol-Lowering Drug Statin
Lowers cholesterol by preventing its production by the liver
120
Diuretic Antihypertensive
Increases the production of urine and thus reduces the volume of fluid in the body
121
Emetic
Promotes vomiting
122
Endocrine Drug
Hormone or Hormone-like drug - Androgens, Estrogens, Progestins, SERMS, Thyroid Hormones & Glucocorticoids
123
Estrogen
Female Hormone that promotes development of secondary sex characteristics and supports reproductive tissues
124
Gastrointestinal Drug
Relieves symptoms of diseases in the gastrointestinal tract - Antacids, Antiulcers, Antidiarrheals, Cathartics, Laxatives, Purgatives, and antiemetics.
125
Glucocorticoid
Hormone from the adrenal cortex that raises blood sugar and reduces inflammation
126
Hypnotic
Produces sleep or a trance-like state
127
Laxative
Weak cathartic
128
Narcotic
Habit-forming drug (potent analgesic) that relieves pain by producing stupor or insensibility - Morphine and Opium
129
Progestin
Female hormone that stimulates the uterine lining during pregnancy and is also used in treatment of abnormal uterine bleeding and for hormonal replacement therapy.
130
Purgative
Relieves constipation Strong cathartic
131
Respiratory Drug
Treats asthma, emphysema, and infections of respiratory system Bronchodilators
132
Sedative
Mildly hypnotic drug that relaxes without necessarily producing sleep Benzodiazepines
133
Stimulant
Excites and promotes activity Caffeine and amphetamines
134
Thyroid Hormone
Stimulates cellular metabolism
135
Tranquilizer
Controls anxiety and severe disturbances of behavior
136
Integumentary System
The skin and its accessory structures (hair, nails, & glands) Integument means covering
137
Epidermis
Thin, Cellular Membrane Layer Contains Keratin Lacks blood vessels, lymphatic vessels, & connective tissue (elastic fibers, cartilage, fat) Made of multilayered cells that die at the same rate they are replaced Within 3-4 weeks after beginning as a basal cell in the deepest part, keratinized cells are sloughed off from the surface of the skin. Constantly renewing itself, process slows with age
138
Squamous Epithelium Stratified Squamous Epithelium
Cells that make up the epidermis, they are flat and scale-like Cells are arranged in several layers to form this
139
Basal Layer
Deepest region of the epidermis Cells are constantly growing and multiplying As cells divide, they are pushed upward and away from the blood supply by a steady stream of younger cells.
140
Stratum Corneum
Most superficial layer of the epidermis Cells flatten, shrink, lose nuclei, die and become filled with keratin.
141
Keratin
Hard protein material found in epidermis, hair, and nails Means horn and is commonly found in the horns of animals
142
Keratinocytes
Cells that are composed of keratin Come from the stratum corneum
143
Melanocytes
Special cells in the basal layer that contain the pigment that is transferred to other cells and give color to the skin. Number in all human races is the same
144
Melanin
Pigment that gives color to skin Amount within each cell accounts for the color differences among the races Eu is black-brown pigment Pheo is red-yellow pigment
145
Albinism
Condition wherein melanin is not formed in the skin leaving hair and skin white Eye color varies and ranges from red to blue to brown depending on the amount of melanin present in the iris.
146
Occulocutaneous Albinism
Affects eyes, skin, and hair
147
Ocular Albinism
Affects the eyes only
148
Dermis
Dense, Fibrous, Connective Tissue layer Composed of interwoven elastin and collagen fibers.
149
Elastin
Protein that is elastic and helps skin to return to its original position when pinched or poked During pregnancy, overstretching of the skin may break the fibers resulting in striae.
150
Collagen
Fibrous protein material found in bone, cartilage, tendons, ligaments and the skin. Tough and resistant but also flexible. In infancy, loose and delicate, becomes harder as the body ages. Support and protect the blood and nerve networks that pass through dermis. Diseases affect connective tissues of the body - ex: scleroderma
151
Striae
Stretch Marks
152
Subcutaneous Layer SubQ
Thick, Fat-Containing Tissue Specializes in the formation of fat Adipocytes are predominant Important in protection of the deeper tissues of the body, as a heat insulator and for energy storage
153
Adipocytes
Fat Cells Manufacture and store large quantities of fat Disposition varies in different areas of the body and among individual people
154
Hair Follicles
Sacs within which each hair fiber grows
155
Lunula
Semilunar whitish region at the base of the nail plate
156
Cuticle
Narrow band of epidermis at the base and sides of the nail plate
157
Paronychium
Soft tissue surrounding the nail border
158
Onycholysis
Loosening of the nail plate with separation from the nail bed
159
Sebaceous Gland
Located in the dermal layer of the skin over entire body with exception of palms, soles, lips. Secrete oily substance Ducts open into hair follicles through which sebum is released Influenced by sex hormones, which can cause them to hypertrophy at puberty and atrophy in old age.
160
Sebum
Oily substance secreted by the sebaceous glands Contain lipids Lubricate the skin and minimize water loss Increased production during puberty contributes to blackhead formation and acne
161
Sweat Glands
Tiny, coiled glands found on almost all body surfaces Most numerous in the palm and sole Originate deep in the dermis and straighten out to extend up through the epidermis
162
Eccrine Sweat Glands
Most numerous sweat-producing exocrine gland in the skin
163
Pore
Tiny opening on the surface of the skin at the end of a sweat gland
164
Sweat Perspiration
Almost pure water, with dissolved materials such as salt making up less than 1% of the total composition Colorless and odorless - odor comes when sweat accumulates on the skin and is caused by the action of bacteria on the sweat Cools the body as it evaporates Controlled by the sympathetic nervous system
165
Apocrine Sweat Glands
Large dermal exocrine glands located in the axilla and genital areas Secretes sweat that in action with bacteria is responsible for human body odor
166
Lesion
Area of abnormal tissue anywhere on or in the body. May be caused by disease or trauma
167
Crust Lesion
Collection of dried serum and cellular debris - Scab: forms from the drying of a body exudate
168
Cyst Lesion
Thick-Walled, closed sac or pouch containing fluid(s) or semisolid material(s) - Pilonidal: found over the sacral area of back in midline and contains hairs - Epidermoid: collection of yellowish, cheesy sebum commonly found on the scalp, vulva, and scrotum
169
Erosion Lesion
Wearing away or loss of epidermis Do not penetrate below the dermo-epidermal junction Occur as a result of inflammation or injury and heal without scarring
170
Fissure Lesion
Groove or crack-like sore - Anal: break in the skin lining of the anal canal
171
Macule Lesion
Flat, pigmented measuring less than 1 cm in diameter Freckles, tattoo marks, flat moles - Patch: large macule, greater than 1 cm in diameter
172
Nodule Lesion
Solid, round or oval elevated measuring 1 cm or more in diameter Enlarged lymph node and solid growths
173
Papule Lesion
Small, solid elevation less than 1 cm in diameter May become confluent and form plaques which are elevated - Skin Tag: small benign growths usually attached to the skin via a stalk (pedunculated) - Pimples
174
Pustule Lesion
Papule containing pus Small abscess (collection of pus) on the skin
175
Ulcer Lesion
Open sore on the skin or mucous membranes - Bedsore: pressure that results from lying in one position (decubitus) - Pressure: usually involve loss of tissue substance and pus or exudate formation
176
Vesicle Lesion
Small collection of clear fluid (serum) Form in skin after burns and may be seen with allergies or dermatitis - Blisters
177
Wheal Lesion
Smooth, swollen (edematous) papule or plaque that is centrally redder than the surrounding skin May be papular, like mosquito bites, or may involve a wide area, as in some allergic reactions Often accompanied by itching and see in hives, anaphylaxis, and insect bites
178
Alopecia Alopecia Areata
Absence of hair from where it normally grows Can be hereditary or may be caused by disease, injury, treatment or may occur with old age Autoimmune disease where hair falls out in round patches without scarring or inflammation
179
Ecchymosis
Bluish-Purplish mark (bruise) on the skin Caused by hemorrhages into the skin from injury or spontaneous leaking of blood from vessels
180
Petechia
Small pinpoint hemorrhage Smaller versions of ecchymoses
181
Purpura
Bleeding into the skin
182
Pruritus
Itching Condition, NOT an inflammation. Make sure it's spelled right Symptom associated with most forms of dermatitis and with other conditions as well Arises as a result of stimulation of nerves in the skin by substances released in allergic reactions or by irritation caused by substances in the blood or by foreign bodies
183
Acne
Chronic papular and pustular eruption of the skin with increased production of sebum
184
Acne Vulgaris
Caused by buildup of sebum and keratin in the pores of the skin
185
Blackhead
Open comedo or comedone which forms when the pore is partially blocked by a sebum plug
186
Whitehead
Closed comedo or comedone which forms when the pore becomes completely blocked
187
Burns
Injury to tissues cause by heat contact Can be caused by dry heat (fire), moist heat (steam or liquid), chemicals, lightning, electricity, or radiation. First-Degree: Superficial epidermal lesions, erythema, hyperesthesia, and no blisters Second-Degree: Epidermal and dermal lesions, erythema, hyperesthesia and blisters. Wound is painful and very sensitive to touch and air Third-Degree: Epidermis and dermis are destroyed (necrosis of skin), subcutaneous (subQ) layer is damaged, leaving charred, white tissue. Wound is insensate Second and Third Degree cause breaches in the skin's protective layer and expose underlying issues, allowing pathogens and toxins direct access to the internal environment of the body. Breach also causes loss of water and electrolytes.
188
Cellulitis
Diffuse, acute infection of the skin marked by local heat, redness, pain and swelling Abscess formation and tissue destruction can occur if appropriate antibiotic therapy is not given Poor lymphatic drainage areas are susceptible to this infection
189
Eczema (Atopic Dermatits)
Inflammatory Skin Disease with erythematous, papulvesicular, or papulosquamous lesions Often begins on face, hands, and at elbow crease or back of knee crease Atopic means pertaining to atopy, meaning out of place or unusual
190
Exanthematous Viral Diseases
Rash due to viral infection - Rubella: German Measles - Rubeola: Measles - Varicella: Chickenpox No longer as common in children because of vaccination programs
191
Erythema Infectiosum
Common exanthematous viral disease marked by fever and rash that has "slapped cheek" appearance on the face and later the arms, buttocks, and trunk Caused by parvovirus
192
Hand-Foot-and-Mouth Disease
Common viral illness in children caused by an enterovirus
193
Gangrene
Death of tissue associated with loss of blood supply Ischemia resulting from injury, inflammation, frostbite, diseases such as diabetes, or arteriosclerosis can lead to necrosis of tissue followed by bacterial invasion and putrefaction (proteins are decomposed by bacteria)
194
Impetigo
Bacterial inflammatory skin disease characterized by vesicles, pustules, and crusted-over lesions Contagious pyoderma, caused by staphylococci or streptococci Systemic use of antibiotics combined with proper cleansing of lesions is effective treatment
195
Psoriasis
Chronic, recurrent dermatosis marked by itchy, scaly, red plaques covered by silvery gray scales Commonly involves forearms, knees, legs, and scalp Isn't infectious or contagious Autoinflammatory disease that can run in families Treatment is palliative (relieves doesn't cure)
196
Scabies
Contagious, parasitic infection of the skin with intense pruritus Commonly affects areas such as the groin, nipples, and skin between the fingers Topical medicated cream to destroy the scabies mites is treatment
197
Scleroderma
Chronic progressive disease of the skin and internal organs with hardening and shrinking of connective tissue Fibrous scar-like tissue forms in the skin, and the heart, lungs, kidneys, and esophagus may be affected as well Skin is thick, hard, and rigid, with areas of both depigmentation and hyperpigmentation Autoimmune disease for which palliative treatment consists of immunosuppressive and anti-inflammatory agents, antifibrotics, and physical therapy
198
Systemic Lupus Erythematosus (SLE) - - - - - - - - - - - Discoid Lupus Erythematosus (DLE) - - Lupus Vulgaris
Chronic inflammatory autoimmune disease Affects joints, skin, kidneys, central nervous system, heart, and lungs Primarily affects females Meaning wolf-like, the shape and color of the erosive skin lesions and tissue loss resembling a wolf attack. Produces a characteristic “butterfly” pattern of redness over the cheeks and nose In more severe cases erythema increases all exposed areas may be involved High levels of certain autoantibodies are found in the patient’s blood Corticosteroids and immunosuppressive drugs are used to control symptoms Photosensitive, scaling, plaque-like eruption of the skin confined to the face, scalp, ears, chest, arms and back Heals with scarring Cutaneous form of tuberculosis
199
Tinea
Infection of the skin caused by a fungus. Antifungal agents are used for treatment Corporis - Ringworm Pedis - Athlete's Foot Capitis - On the Scalp Barbae - Under the Beard Unguium - Affects the nails
200
Urticaria Hives
Acute allergic reaction in which red, round wheals develop on skin Often a reaction to foods or medication. Histamine is released into bloodstream causing pruritus and edema.
201
Vitiligo
Loss of pigment in areas of the skin Form of leukoderma Epidermal melanocytes are completely lost in depigmented areas through an autoimmune process and there is an increased association with autoimmune disorders such as thyroiditis, hyperthyroidism, and diabetes mellitus
202
Callus
Increased growth of cells in the keratin layer of the epidermis caused by pressure or friction
203
Keloid
Excess hypertrophied thickened scar developing after trauma or surgical incision
204
Cicatrix
Normal scar left by a healed wound
205
Keratosis - Actinic Keratosis - Seborrheic Keratosis
Thickened and rough lesion of the epidermis Associated with aging or skin damage Caused by long-term UV light exposure A precancerous lesion that can evolve into squamous cell carcinoma Benign lesion, dark in color, results from overgrown of the upper epidermis
206
Leukoplakia
White, thickened patches on mucous membrane tissue of the tongue or cheek Evolves into squamous cell carcinoma One type is a precancerous lesion that is common in smokers and may be caused by chronic inflammation
207
Nevus Dysplastic Nevi
Pigmented lesion of the skin Commonly known as moles Moles that have atypical cells that may progress to malignant melanoma
208
Verruca - - - - Verruca Vulgaris Plantar Warts Juvenile Warts Venereal Warts
Epidermal growth caused by a virus Commonly known as warts Removed with acids, freezing with liquid nitrogen (cryosurgery), or immune therapy If virus remains in the skin, the wart frequently regrows Most frequent type of wart Occur on the soles of the feet Occur on the hands and face of children Occur on the genitals and around the anus
209
Basal Cell Carcinoma BCC
Malignant tumor of the basal cell layer of the epidermis Most common cancer in humans and most common skin cancer Slow-growing tumor that usually occurs on chronically sun- exposed skin Almost never metastasizes
210
Squamous Cell Carcinoma SCC
Malignant tumor of the squamous epithelial cells in the epidermis. Tumor may grow in places other than the skin, where squamous epithelium is found (mouth, larynx, bladder, esophagus, lungs). Advanced lesions are often nodular and ulcerated. Treatment is removal by surgical excision, cryotherapy, electrodesiccation and curettage, or radiotherapy.
211
Malignant Melanoma
Cancerous growth composed of melanocytes Usually occurs after prolonged exposure to sunlight in sunburned or darkly tanned areas of the skin Usually begins as a mottled, light brown to black macule with irregular borders May turn shades of red, blue and white and may crust on the surface and bleed Frequently appear on upper back, lower legs, arms, head and neck Biopsy is required to confirm the diagnosis of melanoma, and prognosis is best determined by tumor thickness and by the presence of spread to lymph nodes. Treatment of initial lesions consists of excision of tumors and regional lymphadenectomy. Often metastasize to the lung, liver, bone, and brain. For metastatic disease, patients receive drugs that target B-RAF mutations or immunotherapy.
212
ABCDEs of Melanoma
ASSYMETRY - one half unlike the other half BORDER - irregular or poorly circumscribed border COLOR - varies from one area to another; shades of tan, brown, black and sometimes white, red or blue DIAMETER - usually larger than 6 mm (size of a pencil eraser) EVOLUTION - change in lesion over time
213
Kaposi Sarcoma
Malignant, vascular, neoplastic growth characterized by cutaneous nodules. Frequently on arms and legs Range in color from deep pink to dark blue and purple One form of condition is associated with AIDS
214
Angioedema
Swelling around the face
215
Bacterial Analyses
Samples of skin are examined for presence of microorganisms
216
Purulent
Pus-filled
217
Exudate
Fluid that accumulates
218
Fungal Tests
Scrapings from skin lesions, hair specimens, or nail clippings are sent to a lab for culture and microscopic identification of fungal infection
219
Cryosurgery
Use of subfreezing temperature achieved with liquid nitrogen application to destroy tissue
220
Curettage
Use of a sharp dermal curette to scrape away a skin lesion
221
Electrodesiccation
Tissue is destroyed by burning with an electric spark
222
Mohs Surgery
Thin layers of malignant tissue are removed and each slice gets examined microscopically to check for adequate extent of resection
223
Skin Biopsy
Epidermal melanocytes are completely lost in depigmented areas through an autoimmune process
224
Punch Biopsy
Surgical instrument removes a core of tissue obtained by rotation of its sharp, circular edge
225
Shave Biopsy
Tissue is excised using a cut parallel to the surface of the surrounding skin
226
Skin Tests
Substances are injected intradermally or applied to the skin, and results are observed
227
Patch Test
Allergen treated piece of gauze or filter paper is applied to the skin, and if the skin becomes red or swollen, the result is positive
228
Scratch Test
Several scratches are made in the skin, and a very minute amount of test material is inserted into the scratches
229
Schick Test
Used to check for diptheria
230
Purified Protein Derivative (PPD) or Mantoux Test
Used to check for tuberculosis
231
Rule of Nines
Tool medical providers use to quickly assess and estimate the severity of burns, which helps guide their treatment decisions. Adults: arm is 9 (4.5%), leg is 18 (9%), torso is 36 (18%), head is 9 (4.5%), and groin is 1 (1%). Numbers are adjusted for children and infants because their proportions are slightly different. Children: shoulder to elbow is 4%, elbow to wrist is 3%, wrist to fingers is 2.5%, hip to knee is 4%, knee to ankle is 5.5%, ankle to toes is 3.5%, torso is 13%, neck is 2%, head is 6.5%, groin is 1%. Infant: arm is 9%, leg is 14%, torso is 13%, head is 18%, groin is 1%.
232
Psoralen Ultraviolet A Light Therapy (PUVA)
Treatment for psoriasis and other skin conditions
233
Biopsy (Bx)
Medical procedure where a sample of cells or tissue is taken from a patient for the purposes of examination and diagnosis
234
Bone
Dense, hard connective tissue compsing the skeleton Long (femur), short (carpal), flat (scapula), sesamoid (patella)
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Cartilage
Flexible, connective tissue Found in immature skeleton, at the epiphyseal growth plate, and on joint surfaces
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Ossification Osteogenesis
Bone Formation - process in which cartilage is replaced with bone Formation depends largely on proper supply of calcium and phosphorus to bone tissues
237
Osteogenic Cells
Found deep in bone tissues Only bone cells that can undergo mitosis (dividing to make new cells) Undifferentiated bone cells that develop into osteoblasts
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Osteoblasts
Immature osteocytes that produce bony tissue replacing cartilage during ossification These work with osteoclasts throughout life to keep bones healthy and strong When a bone breaks, these lay down mineral bone matter (calcium salts)
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Osteocytes
Osteoblasts that have become trapped in the matrix of bone Responsibility is to nourish and maintain bone tissue Most common bone cells
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Osteoclasts
Large cells that function to reabsorb, or digest, bony tissue Also called bone phagocytes Digest bone tissue from inner sides of bone to enlarges inner bone cavity so the bone does not become overly thick and heavy Originate from two types of white blood cells: monocytes and macrophages These work with osteoblasts throughout life to keep bones healthy & strong When a bone breaks, these remove excess bone debris (smooth out bone)
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Vitamin D
Necessary to facilitate the movement of calcium across the lining of the intestines
242
Calcium
In bones combines with phosphorus to give bones rigid structure Important from proper muscle and nervous tissue function Level in blood is tightly regulated by hormones that stimulate release from bones when blood levels are low and stimulate storage when blood levels are high
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Calcium Phosphate
Major calcium salt in bones
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Phosphorus
In bones combines with calcium to give bones rigid structure
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Fracture
Most common pathologic condition of bones Usually a result of trauma Can be result of severe muscle spasms and/or weakening of the bone from disease Classification is based on complexity, location, and other distinguishing characteristics Some types occur only in specific bones
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Pathologic Fracture
Result from the weakening of bone because of disease such as neoplasms, Paget's disease, or osteoporosis
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Depression Fracture
Happens when a piece of skull is broken free and is pushed inward (depressed) toward the brain
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Fracture Treatment
Involves putting the bone back into proper place, if necessary, and then immobilization
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Reduction
Process of putting bone back into proper place for fracture treatment Can be performed open or closed. Closed - performed through manipulation of the affected area to ease bone back into position Open - surgical procedure performed by opening skin around affected area and manipulating bone directly - often includes fixation with rods, plates, screws, etc.
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Immobilization
Most of the time can be achieved by use of a cast Some areas, such as clavicle or ribs, cannot be casted, so other means are used
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Osseous Tissue
Specialized connective tissue that bones are chiefly composed of
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Diaphysis
Shaft, or middle region, of a long bone
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Epiphysis
Each end of a long bone
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Epiphyseal Line or Plate
Represents an area of cartilage tissue that is constantly being replaced by new bone tissue as the bone grows Commonly knows as the growth plate Cartilage cells at the edges form new bone which is responsible for lengthening bones during childhood an adolescence Plate calcifies and disappears when bone has achieved full growth
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Metaphysis
Flared portion of bone that lies between epiphysis and diaphysis, adjacent to epiphyseal plate
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Periosteum
Strong, fibrous, vascular membrane that covers the surface of long bones, except at ends of epiphyses. Has extensive nerve supply Covers all bones
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Articular Cartilage
Very smooth, strong, slick tissue that covers the end of long bones and the surface of any bone that meets another bone to form a joint Cushions joint and allows it to move smoothly and efficiently When two bones come together to form a joint, the bones do not touch, this that caps the end of one bone comes into contact with this that caps the other bone Does not disappear like cartilage of epiphyseal line or plate, but is present throughout life
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Compact (Cortical) Bone
Layer of hard, dense bone that lies under periosteum in all bones and is located chiefly around the diaphysis of long bones
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Haversian Canals
System of small canals in the compact (cortical) bone containing blood vessels that bring oxygen and nutrients to the bone and remove waste products like carbon dioxide
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Medullary Cavity
Area of compact bone that is tunneled out in the central shaft of the long bones that contains yellow bone marrow
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Yellow Bone Marrow
Composed chiefly of fat cells
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Cancellous Bone
Sometimes called spongy or trabecular bone Much more porous and less dense that compact bone Mineral matter laid down in series of separated bony fibers making up spongy latticework Spaces contain red bone marrow
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Trabeculae
Interwoven fibers found largely in epiphyses and metaphyses of long bones and in the middle portion of most other bones
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Red Blood Cells
Consists of immature and mature blood cells in various stages of development
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Hematopoeisis
Production of all types of blood cells in the bone marrow
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Sutures
Name of the joints where cranial bones join each other
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Fontanelles
Soft Spots - "Little Fountains" Gaps of unossified tissue in the skull at birth
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Frontal Bone
Forms the forehead and the roof of the bony sockets that contain the eyes
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Parietal Bone
Two bones (one bone on each side of the skull) that form the roof and upper part of the sides of the cranium
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Temporal Bone
Two bones that form the lower sides and base of the cranium Each bone encloses an ear and contains a fossa for joining with the mandible
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Temporomandibular Joint (TMJ)
Area of connection between temporal and mandibular bones
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Mastoid Process
Round process of the temporal bone behind the ear
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Styloid Process
Projects downward from the temporal bone
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Occipital Bone
Forms the back and base of the skull and joins the parietal and temporal bones, forming a suture
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Foramen Magnum
Opening in the inferior portion of the occipital bone that the spinal cord passes through
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Sphenoid Bone
Bat-shaped bone that extends behind the eyes and forms part of the base of the skull Serves as an anchor to hold frontal, occipital and ethmoid bones together
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Sella Turcica "Turkish Saddle"
Depression in the sphenoid bone where the pituitary gland is located
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Ethmoid Bone
Thin, delicate bone that supports nasal cavity and forms part of the sockets of the eyes Composed primarily of spongy, cancellous bone that contains numerous small holes
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Bone Process
Enlarged areas that extend out from bones and serve as attachments for muscles, tendons, and ligaments
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Bone Depression
Openings or hollow regions serving as connections between bones, or passageways for blood vessels and nerves
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Bone Head
Rounded end of bone
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Condyle
Rounded knuckle-like process, at the end of a bone
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Epicondyle
Small rounded process above condyle
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Trochanters
Large and small processes for tendon attachments on the femur
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Tuberosity Tubercle
Round elevation where tendons and muscles attach on the humerus, calcaneus (heel bone), and pelvis)
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Fissure (Depression)
Narrow groove or slit-like opening ie: orbital fissure (eye socket)
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Foramen (Depression)
Opening for blood vessels and nerves ie: foramen magnum of the skull
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Fossa (Depression)
Shallow cavity in or on a bone ie: olecranon (elbow) fossa on humerus
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Sinus (Depression)
Hollow cavity within bone ie: sinuses of the skull
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Nasal Bones
Two slender bones that support the bridge of the nose They join with the frontal bone superiorly and form part of this septum
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Lacrimal Bones
Two small, thin bones located at corner of each eye Contain fossae for the gland and canals for passage of the duct
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Maxillary Bones
Two large bones that compose massive upper jawbones Joined by suture in median plane
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Cleft Palate
When the two bones of the maxillary do not come together normally before birth
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Mandibular Bone
Lower jawbone joins skull at the region of the temporal bone forming the TMJ on either side of the skull Only facial bone capable of movement which is necessary for activities such as chewing and speaking
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Mastication
Chewing
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Alveoli
Both maxilla and mandible contain these sockets that have teeth embedded in them
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Zygomatic Bones
Two bones, one on each side of the face, that form high portion of the cheek
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Vomer
Thin, single, flat bone that forms lower portion of nasal septum
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Sinuses Air Cavities
Located in specific places within the cranial and facial bones to lighten the skull and warm and moisten the air as it passes through
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Vertebral (Spinal) Column
Composed of 26 bone segments that are arranged in five divisions from base of skull to tailbone
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Vertebrae
Name of bone segments in spinal column
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Intervertebral Discs
Fibrocartilaginous structures that separate the bones of the spinal column Provides flexibility and absorbs shocks to spinal column
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Spinal Disc Herniation
Occurs when tear in an intervertebral disc causes a portion of the disc to bulgd out into the neural canal
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Vertebral Body
Inner, thick, round anterior portion of each bone segment in the spinal column
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Spinous Process
Bony projection off the posterior of each vertebra Serves to attach muscles and ligaments
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Transverse Process
Bony projection on either side of each vertebra Serves as a point of attachment for muscles that help move the vertebrae as well as ligaments that stabilize the vertebral column
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Lamina
Flattened or arched part of the vertebral arch, forming the roof of the spinal canal Provides support and protection for the backside of the spinal cord Connects spinous process and transverse process
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Neural Canal Spinal Canal
Space between the vertebral body and the vertebral arch through which the spinal cord passes
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Cervical Vertebrae
First seven bones of the vertebral column Form the bony aspect of the neck C1-C7 Do not articulate (join) with the ribs
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Thoracic Vertebrae
Second set of twelve vertebral bones T1-T12 These vertebrae articulate with the ribs
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Lumbar Vertebrae
Third set of five vertebral bones L1-L5 Strongest and largest of the vertebrae Do not articulate with the ribs
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Sacral Vertebrae Sacrum
Five separate bones that fuse in a young child. In an adult, the sacrum is a slightly curved, triangularly shaped bone.
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Coccyx
The tailbone - also a fused bone formed from four small coccygeal bones
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Clavicle
Collar Bone Slender bone, positioned anteriorly (ventrally), one on each side Connects the breastbone (sternum) to each shoulder blade (scapula)
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Scapula Plural: Scapulae
Shoulder Blade One of two flat, triangular bones on each dorsal side of the thorax
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Acromion
Extension of the scapula that joins with the clavicle to form a joint above the shoulder
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Acromioclavicular (AC) Joint
Formed by the joining of the the acromion and the scapula
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Glenohumeral Joint
Shoulder joint
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Sternum
Breastbone Flat bone extending ventrally down the midline of the chest Upper part articulates on the sides with the clavicle and ribs Lower, narrower portion is attached to the ribs, diaphragm and abdominal muscles
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Xiphoid Process
Lowest part of the sternum
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Manubrium
Uppermost portion of the sternum
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Ribs
There are twelve pairs 1-7 join with the sternum anteriorly and with the vertebral column posteriorly 8-10 join with the vertebral column posteriorly, but join the 7th anteriorly instead of attaching to the sternum 11 and 12 are completely free at their anterior ends
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Costal Cartilages
Cartilaginous attachments that join the first seven pairs of ribs to the sternum anteriorly
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True Ribs
Ribs one through seven Join with the sternum anteriorly and with the vertebral column posteriorly
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False Ribs
Ribs eight through ten Join with the vertebral column posteriorly but join the 7th anteriorly instead of attaching to the sternum
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Floating Ribs
Ribs eleven and twelve Completely free at their anterior ends
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Humerus
Upper Arm Bone Large head is rounded and joins with the glenoid fossa of the scapula to form the shoulder or the glenohumeral joint
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Labrum
Rim of fibrocartilage that guides the humerus as it moves in the glenoid fossa
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Rotator Cuff
Group of muscles with tendons that surround the shoulder joint
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Ulna
Medial forearm bone
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Olecranon
Proximal bony process of the ulna at the elbow Bony point formed when the elbow is bent Elbow bone
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Radius
Lateral forearm bone In line with thumb
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Carpals
Two rows of four bones in the wrist
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Metacarpals
Five bones in the palm of the hand
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Phalanges Singular: Phalanx
Finger bones Each finger (except the thumb) has three phalanges: a proximal, a middle, and a distal phalanx The thumb has only two phalanges: a proximal and a distal phalanx
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Pelvic Girdle Pelvis
Collection of bones that supports the trunk of the body Articulates with the femur to form the hip joint Adult is composed of three pairs of fused bones: iium, ischium, and pubis Joins with the single posteriorly (dorsally) located sacrum
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Ilium
Uppermost and largest portion of the pelvis
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Sacoiliac Joints
Joining of two parts of the ilium and the sacrum on either side Very firm and very little motion occurs in these joints
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Iliac Crest
Superior part of the ilium Filled with red bone marrow and serves as attachment for abdominal wall muscles as well as strong muscles of the him and buttocks
340
Ischium
Inferior or lower part of the pelvis, which along with ligaments, tendons and muscles attached to it are what you sit on
341
Pubis
Anterior part of the pelvis
342
Pubic Symphysis
Two pubic bones join by way of a cartilaginous disc Area is quite rigid
343
Pelvic Cavity
Region within the ring of bone formed by the pelvic girdle Rectum, sigmoid colon, bladder, and female reproductive organs lie within and are protected by the rigid architecture of the pelvic girdle
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Femur
Thigh bone Longest bone in the body At proximal end it has a rounded head that fits into a depression, or socket, in pelvis
345
Acetabulum
Socket in pelvis that femur fits into named because of resemblance to rounded cup Romans used for vinegar (acetum)
346
Hip Joint
Head of the femur and the acetabulum form this ball-and-socket joint
347
Patella
Kneecap Small, flat bone that lies in front of the articulation between the femur and the tibia Sesamoid bone surrounded by protective tendons and held in place by muscle attachments
348
Knee Joint
Created by meeting of femur, tibia, and patella
349
Tibia
Shin Bone Larger of the two bones of the lower leg Runs under the skin in the front part of the leg Joins with the femur and patella proximally
350
Fibula
Smaller of the two lower legs bones Thin bone, well hidden under leg muscles, runs parallel to tibia
351
Malleolus
Round process on both sides of the ankle joint
352
Medial Malleolus
Distal end of the tibia forms a flare creating bony prominence at the inside of the ankle
353
Lateral Malleolus
Distal end of the fibula forms a flare creating bony prominence on the outside of the ankle
354
Ankle Joint
Created by meeting of tibia, fibula and talus
355
Talus
First of the tarsal bones and one of the bones that forms the ankle joint
356
Tarsals
Bones of the hind and mid parts of the foot Seven short bones resemble carpal bones of the wrist but are larger
357
Calcaneus
Heel Bone Largest of the tarsal bones
358
Metatarsals
Five bones between the tarsals and phalanges Similar to metacarpals, each articulates with the phalanges of the toes
359
Phalanges of the toes
Bones of the forefoot Two phalanges in the big toe (a proximal and a distal phalanx) and three in each of the other toes (a proximal, a middle, and a distal phalanx)
360
Tendon
Fibrous connective tissue that binds muscles to bones
361
Ligament
Fibrous connective tissue that binds bones to other bones Bands, sheets, or strands located in and around joints Anchor one bone to another Add considerable strength to joint capsule in critical areas
362
Orthopedist
Medical doctor who specialize in bone, joint and muscle conditions
363
Physiatrist
Medical doctor specializing in rehabilitation
364
Joint Articulation
Coming together of tow or more bones
365
Suture Joints
immovable joints ie: between skull bones
366
Synovial Joints
Freely movable joints
367
Ball-and-Socket Type Joints
Hip Shoulder
368
Hinge Type Joints
Elbow Knee Ankle
369
Joint Capsule
Surrounds synovial joint Composed of fibrous tissue
370
Articular Cartilage
Smooth, glistening white tissue that covers bones at the joint
371
Synovial Membrane
Lies under the joint capsule in the synovial cavity
372
Synovial Cavity
Space between the bones Filled with special lubricating fluid produced by synovial membrane
373
Synovial Fluid
Contains water and nutrients that nourish articular cartilage Minimizes friction allowing joints to move smoothly Similar in viscosity to egg whites
374
Meniscus
Crescent-shaped fibrocartilaginous structure Partly divides joint cavity Acts as protective cushion Helps evenly transfer weight from one bone to another Present in a few joints, but most well known are ones in the knee
375
Bursa Plural: Bursae
Closed sac of synovial fluid lines with synovial membrane Located near, but not within joint Present wherever two types of tissue need to slide past one another with as little friction as possible Serve as layers of lubrication between tissues Common sites are between the following: * tendons and bones, * ligaments and bones * skin and bones where bony anatomy is prominent Common locations are the following: * elbow (olecranon) joint * knee (prepatellar) joint * shoulder (subacromial) joint
376
Arthritis
Inflammation of any joint
377
Ankylosing Spondylitis
Chronic, progressive arthritis with stiffening of joints, primarily of the spine
378
Gout Gouty Arthritis
Inflammation and painful swelling in an around joints Caused by uric acid crystal deposits
379
Hyperuircemia
Congenital defect in metabolism of uric acid causes too much to accumulate in the blood
380
Podagra
Name for gouty arthritis when it affects the big toe
381
Osteoarthritis (OA) Degenerative Joint Disease
Progressive, degenerative joint disease with loss of articular cartilage and hyper trophy of bone at articular surfaces
382
Rheumatoid Arthritis
Chronic joint condition with inflammation and pain Caused by autoimmune reaction against joint tissue, particularly the synovial membrane
383
Bony Ankylosis
Fibrous tissue forms and calcifies at the joint preventing movement
384
Pyrexia
Fever
385
Bunion
Enlargement of bone or tissue around the joint at base of big toe
386
Halux Valgus
Another name for bunion Great toe; abnormal angulation of the toe
387
Carpal Tunnel Syndrome
Compression of the median nerve as it passes between the transverse ligament, and bones and tendons of the wrist
388
Dislocation
Displacement of a bone from its joint
389
Shoulder Dislocation
Disruption of articulation between head of the humerus and the glenoid fossa of the scapula
390
Hip Disocation
Disruption of articulation between the head of the femur and the acetabulum of the pelvis
391
Reduction
Treatment for dislocation which restores bones to their normal positions
392
Subluxation
Partial or incomplete dislocation
393
Ganglion Cyst
Fluid-filled sac arising from joint capsules or tendons in the hand
394
Herniation of Intervertebral Disc
Abnormal protrusion of an intervertebral disc into the spinal canal or spinal nerves Commonly referred to as a "slipped disc"
395
Sciatica
Pain radiating down the leg
396
Microdiscectomy
Removal of a portion of the protruding disc
397
Lyme Disease Lyme Arthritis
Chronic, recurrent disorder marked by severe arthritis, myalgia or malaise Caused by bacterium carried by a tick
398
Sprain
Injury, often the result of trauma, involving overstretching of the ligaments around the joint
399
Strain
Injury involving overstretching of the muscle
400
Striated Muscle Tissue
Makes up the muscles connected to the bones of the skeleton Also known as skeletal muscle Voluntary muscles, controlled by the conscious mind through central and peripheral nervous system Move all bones, as well as controlling all facial expression and eye movements Cells have appearance of pattern of dark and light bands in the cytoplasm under the microscope Arranged un bundles and each connects with neuron of the of the nervous system providing a way to communicate with the brain. Don't work properly without effect communication from the nervous system Each cell has only one nucleus
401
Fibril
Pattern of dark and light bands in cytoplasm of striated muscles
402
Smooth Muscle Tissue
Found throughout body in visceral organs, secretory ducts, and walls of blood vessels Called visceral because of connection to visceral organs Involuntary muscles, not controlled by conscious mind Uniform shape and appearance under microscope Each cell has only one nucleus Arranged in sheets that wrap around structures Some interaction with nervous system Muscles can respond to hormonal and other local stimuli
403
Cardia Muscle Tissue
Only found in the heart Shares qualities with both skeletal and visceral muscle tissues Striated but structurally different due to branching appearance and have one or two nuclei. Involuntary muscle that cannot be controlled by the conscious mind Do not require interaction with nervous system for all functions Respond to hormonal and local stimuli and electronically communicate with surrounding cells to coordinate muscular contractions
404
Origin
Point of attachment of the muscle to the stationary bone Most often, lies proximal in skeleton For biceps, it's at the scapula
405
Insertion
Point of junction of the muscle to the bones that moves Most often, lies distal in skeleton For biceps, its at the radius
406
Orbicularis Oculi
Closes eyelids and wrinkles forehead
407
Sternocleidomastoid
Turns head
408
Pectoris Major
Adducts, Flexes, Rotates shoulder inward
409
Biceps Brachii
Flexes and supinates forearm
410
Triceps Brachii
Extends forearm and adducts arm
411
Deltoid
Abducts shoulder
412
Trapezius
Elevates shoulder
413
Masseter
Closes jaw for chewing
414
Temporalis
Closes Jaw
415
Occipitofrontalis
Raises eyelids and Draws scalp backward
416
Gluteus Maximus
Extends, Abducts, and Rotates thigh externally
417
Hamstrings
Flex the knee and Extend the hip Smimembranosus Biceps Femoris Semitendinosus
418
Gastrocnemius (Superficial)
Bends knee and lifts hill off ground
419
Soleus (Deep)
Raises the heel
420
Achilles Tendon
Helps with "push-off action when walking"
421
Gluteus Medius
Abducts the thigh
422
Quadriceps
Extends the knee
423
Flexion
Decreasing the angle between two bones Bending a limb
424
Extension
Increasing the angle between two bones Straightening out a limb
425
Abduction
Movement away from the midline of the body
426
Adduction
Movement toward the midline of the body
427
Rotation
Circular movement around an axis (central point). Internal: toward the center of the body External: away from center of the body
428
Dorsiflexion
Decreasing angle of the ankle joint so that the foot moves upward, toward the knee or ceiling
429
Plantar Flexion
Motion that moves the foot downward toward the ground as when pointing the toes or stepping on the gas pedal.
430
Supination
Hand and Forearm: where the elbow is bent, act of turning the palm up Foot : outward roll of the foot/ankle during normal motion
431
Pronation
Hand and Forearm: where the elbow is bent, act of turning the palm down Foot: inward roll of the foot/ankle during normal motion