Voies métabolique Flashcards

1
Q

Quelles sont les 10 voies métaboliques

A
  1. Glycolyse
  2. Activation du cycle de Krebs
  3. Cycle de Krebs
  4. Gluconéogenèse
  5. Cycle futile
  6. Glycogénogenèse
  7. Glycogénolyse
  8. Lipogenèse
  9. B-oxydation
  10. Métabolisme du cholestérol
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2
Q

GLYCOLYSE

Enzymes clé, activateur et inhibiteurs

A
  1. Hexokinase ~ Insuline ~ G-6-P
  2. PFK-1 ~ AMP; F-2,6-diP ~ ATP; Citrate
  3. Pyruvate kinase ~ F-1,6-diP; insuline ~ ATP/ADP; acetyl-CoA; glucagon
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3
Q

ACTIVATION DU CYCLE DE KREBS

Enzymes clé, activateur et inhibiteurs

A

Pyruvate deshydrogenase ~ Pyruvate ~ Acetyl-CoA; ATP; NADH

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4
Q

CYCLE DE KREBS

Enzymes clé, activateur et inhibiteurs

A
  1. Citrate synthase ~ Acetyl-CoA ~ citrate; succinyl-CoA; ATP; NADH
  2. Isocitrate deshydrogenase ~ ADP; NAD+ ~ NADH; ATP
  3. a- cetoglutarate deshydrogenase ~ X ~ ATP/AMP; NADH; succinyl-CoA
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5
Q

GLUCONÉOGENÈSE

Enzymes clé, activateur et inhibiteurs

A
  1. Pyruvate carboxylase ~ Acetyl-CoA ~ X

2. Fructose-1,6-diphosphatase ~ X ~ F-2,6-diP

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6
Q

CYCLE FUTILE

Enzymes clé, activateur et inhibiteurs

A

PFK-2 ~ insuline; F-6-P ~ Glucagon

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7
Q

GLYCOGENOGENESE

Enzymes clé, activateur et inhibiteurs

A

Glycogene synthase ~ Insuline ~ Glucagon

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8
Q

GLYCOGENOLYSE

Enzymes clé, activateur et inhibiteurs

A

Phosphorylase ~ Glucagon ~ Insuline

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9
Q

LIPOGENESE

Enzymes clé, activateur et inhibiteurs

A

Acetyl-CoA carboxylase ~ citrate; acetyl-CoA; insuline ~ acyl-CoA; glucagon

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10
Q

B-OXYDATION

Enzymes clé, activateur et inhibiteurs

A
  1. Carnitine acyltransferase ~ X ~ Malonyl-CoA

2. Lipase ~ Glucagon ~ X

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11
Q

METABOLISME DU CHOLESTEROL

Enzymes clé, activateur et inhibiteurs

A

HMG-CoA reductase ~ Insuline ~ Glucagon; cholesterol

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