W10: Antifungals / Antivirals

Question 1

What are the 2 types of fungal infections and what is an example of each?

Answer 1

Opportunistic (in pts who are immunocompromised or immunosuppressed, take antibiotics, chemo, etc) Ex: candidiasis (thrush)

Pathogenic (can occur in healthy patients.) Ex: histoplasmosis - caused by breathing in spores of fungus found in bird droppings

Question 2

antifungal drugs are also knowns as ____

Answer 2

Antimycotic drugs

Question 3

What is the difference between a fungistatic and fungicidal drug?

Answer 3

Fungistatic inhibits growth of fungi, fungicidal kills fungus

Question 4

What is an example of an antifungal drug for systemic infections?

Answer 4

Amphotericin B

Question 5

How is amphotericin B distributed?

Answer 5

IV only.

Question 6

Is amphotericin B broad spectrum or narrow spectrum?

Answer 6

Broad spectrum

Question 7

Patients taking amphotericin B should be closely monitored for

Answer 7

Delirium, hemodynamic instability, wheezing and hypoxia

Question 8

____ is a topical antifungal medication

Answer 8

Nystatin

Question 9

Antivirals can be used to treat:

Answer 9

Influenza, herpes, hepatitis A, B & C

Question 10

___ is an antiviral used for influenza A & B

Answer 10

Oseltamivir (Tamiflu)

Question 11

Oseltamivir is only effective if given within ____ hours of onset of symptoms

Answer 11

48 hours

Question 12

Patients with ____ should use oseltamivir with caution

Answer 12

Renal impairment

Question 13

____ is an antiviral used to treat herpes.

Answer 13

Acyclovir