Water soluble vitamins

Question 1

B1

Answer 1

Thiamine

Question 2

primary function of thiamine

Answer 2

decarboxylation of alpha-keto acids (carbohydrate metabolism)

Question 3

Deficiency of thiamine

Answer 3

Beriberi (peripheral neuropathy, heart failure)

Wernicke-Korsakoff syndrome

Question 4

B2

Answer 4

Riboflavin

Question 5

Primary function of riboflavin

Answer 5

Mitochondrial hydrogen carrier (FMN, FAD)

Question 6

Deficiency of riboflavin

Answer 6

Angular cheilosis, stomatitis, glossitis

Normocytic anemia

Question 7

B3

Answer 7

Niacin

Question 8

Primary function of niacin

Answer 8

Hydrogen acceptor (NAD/NADH)

Question 9

Deficiency of niacin

Answer 9

Pellagra (dermatitis, dementia, diarrhea)

Question 10

B6

Answer 10

Pyridoxine

Question 11

Primary function of pyridoxine

Answer 11

Transamination of AA (amino acid synthesis)

Question 12

Deficiency of pyridoxine

Answer 12

Cheilosis, stomatitis, glossitis

peripheral neuropathy

Question 13

B9

Answer 13

folate, folic acid

Question 14

Primary function of folate, folic acid

Answer 14

Hydroxymethyl/formyl carrier (purine and thymine synthesis)

Question 15

Deficiency of folate, folic acid

Answer 15

Megaloblastic anemia

Neural tube defects (fetus)

Question 16

B12

Answer 16

Cobalamin

Question 17

Primary function of cobalamin

Answer 17

Isomerase and methyltransferase cofactor (DNA and methionine synthesis)

Question 18

Deficiency of cobalamin

Answer 18

Megaloblastic anemia
Neurologic deficits (subacute combined degeneration of the spinal cord)

Question 19

Vit C

Answer 19

Ascorbic acid

Question 20

Primary function of ascorbic acid

Answer 20

Hydroxylation of proline and lysine (collagen synthesis)

Question 21

Deficiency of ascorbic acid

Answer 21

Scurvy