Week 1 Flashcards
Drug
exogenous chemical agent used to modify
Pharmacology –
study of the use of chemical..agents for therapeutic purposes
Toxicology –
Adverse effects of a drug
Receptor –
site of action of a drug
Agonist –
Drug that mimics a biological effect
Antagonist –
Drug that inhibits a biological effect
What is pharmacodynamics?
Pharmacodynamics is the study of how a drug acts to achieve a response. what the drugs be doing.. it is the existing biology to inhibit or increase it.
What is the basic principle of pharmacodynamics?
The basic principle is that drugs have specific molecular targets (receptors) in the body.
How does lidocaine function?
Lidocaine blocks the activity of Na+ channels and prevents the transmission of sensory signals.
How does penicillin work?
Penicillin binds to proteins that build the cell wall and prevents the bacterium from replicating. good antibiotic agent
What is pharmacodynamics vs pharmacokinetics
pharmacodynamtics is whta the drug does to the body while kinetics is what the drug is actually doing within the body
What are Voltage Gated Ion Channels?
They are ion channels that open or close in response to changes in membrane potential.
What are Ionotropic (ligand-gated) Ion Channels?
They are ion channels that open in response to the binding of a ligand.
Name a type of Ionotropic Ion Channel.
Glutamate receptors.
Name another type of Ionotropic Ion Channel.
5-hydroxytryptamine (5-HT3) receptor.
Name another type of Ionotropic Ion Channel.
G-aminobutyric acid receptors.
Name another type of Ionotropic Ion Channel.
Glycine receptors.
What effect do Ionotropic Ion Channels have on the membrane?
They can depolarize or hyperpolarize the membrane.
Which ions are involved in the function of Ionotropic Ion Channels?
Na+, K+, Ca2+.
