week 1 - reproductive hormones Flashcards

(69 cards)

1
Q

what are the 15 reproductive hormones?

A
  • GnRH
  • LH
  • FSH
  • prolactin
  • oxytocin
  • estradiol
  • progesterone
  • testosterone
  • inhibin
  • activin
  • PGF2a
  • hCG
  • PGE2
  • eCG
  • placental lactogen
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2
Q

which hormones are neuropeptides?

A
  • GnRH
  • oxytocin
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3
Q

which hormones are glycoproteins?

A
  • LH
  • FSH
  • inhibin
  • activin
  • hCG
  • eCG
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4
Q

which hormones are proteins?

A
  • prolactin
  • placental lactogen
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5
Q

which hormones are steroids?

A
  • estradiol
  • progesterone
  • testosterone
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6
Q

which hormones are fatty acids?

A
  • PGF2a
  • PGE2
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7
Q

where does GnRH come from?

A
  • hypothalamus
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8
Q

where do LH and FSH come from?

A
  • anterior pituitary (gonadotrophs)
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9
Q

where does prolactin come from?

A
  • anterior pituitary (lactotrophs)
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10
Q

where does oxytocin come from?

A
  • synthesized in the hypothalamus (and corpus luteum in females)
  • stored in the posterior pituitary
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11
Q

where does estradiol come from in males?

A
  • sertoli cells
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12
Q

where does testosterone come from in males?

A
  • leydig cells
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13
Q

where do inhibin and activin come from in males?

A
  • sertoli cells
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14
Q

where does estradiol come from in females?

A
  • granulosa cells
  • placenta
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15
Q

where does progesterone come from in females?

A
  • corpus luteum
  • placenta
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16
Q

where does testosterone come from in females?

A
  • theca interna
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17
Q

where does inhibin come from in females?

A
  • granulosa cells
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18
Q

where does activin come from in females?

A
  • placental cells
  • granulosa cells
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19
Q

where does PGF2a come from in males?

A
  • vesicular glands
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20
Q

where does hCG come from in males?

A
  • trophoblast of blastocyst (chorion)
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21
Q

where does PGF2a come from in females?

A
  • endometrium
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22
Q

where does PGE2 come from in females?

A
  • ovary
  • uterus
  • embryonic membranes
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23
Q

where does hCG come from in females?

A
  • trophoblast of blastocyst (chorion)
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24
Q

where does eCG come from in females?

A
  • chorionic girdle cells
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25
where does placental lactogen come from in females?
- placenta
26
what is the target of GnRH in males and females?
- anterior pituitary
27
what is the target of LH in males?
- leydig cells in testis
28
what is the target of FSH in males?
- sertoli cells in testis
29
what is the target of prolactin in males?
- testis and brain
30
what is the target of oxytocin in males?
- smooth muscle cauda - ductus deferens - ampulla
31
what is the target of LH in females?
- theca interna and CL in ovary
32
what is the target of FSH in females?
- granulosa cells in ovary
33
what is the target of prolactin in females?
- mammary cells - corpus luteum if you're a RAT
34
what is the target of oxytocin in females?
- myo/endometrium - myoepithelial cells
35
what is the target of estradiol in males?
- brain - - inhibits long bone growth
36
what is the target of testosterone in males?
- accessory sex glands - tunica dartos - seminiferous epithelium - skeletal muscle
37
what is the target of inhibin and activin in males and females?
- anterior pituitary (gonadotrophs)
38
what is the target of estradiol in females?
- hypothalamus - repro tract - mammary gland
39
what is the target of progesterone in females?
- hypothalamus - myo/endometrium - mammary gland
40
what is the target of testosterone in females?
- brain - skeletal muscle - granulosa cells
41
what is the target of PGF2a in males?
- epididymis
42
what is the target of hCG in males?
- fetal testis
43
what is the target of PGF2a in females?
- CL - myometrium - ovulatory follicles
44
what is the target of PGE2 in females?
- CL - oviduct
45
what is the target of hCG and eCG in females?
- ovary
46
what is the target of placental lactogen in females?
- mammary gland
47
what is the action of GnRH in females and males?
- increase FSH and LH
48
what is the action of LH in males?
- increase testosterone
49
what is the action of FSH in males?
- sertoli cell function
50
what is the action of prolactin in males?
- maternal behaviour
51
what is the action of oxytocin in males?
- PGF2a synthesis - pre ejaculatory movement of sperm
52
what is the action of LH in females?
- ovulation - CL function - progesterone secretion - follicle development
53
what is the action of FSH in females?
- follicle development - estradiol synthesis
54
what is the action of prolactin in females?
- lactation - maternal behaviour - CL function in some species
55
what is the action of oxytocin in females?
- uterin motility - PGF2a synthesis - milk ejection
56
what is the action of estradiol in males?
- sexual behaviour
57
what is the action of testosterone in males?
- anabolic growth - spermatogenesis - secretions of accessory sex glands
58
what is the action of inhibin in males and females?
- decrease FSH
59
what is the action of activin in males and females?
- increase FSH
60
what is the action of PGF2a in males?
- affect metabolic activity of sperm - epididymal contractions
61
what is the action of hCG in males?
- promote growth of fetal testis
62
what is the action of PGF2a in females?
- luteolysis - uterine horn tone and contractions - ovulation
63
what is the action of estradiol in females?
- sexual behaviour - GnRH production - secretory activity of tract - uterine motility
64
what is the action of progesterone in females?
- endometrial secretion - stop GnRH production - stop reproductive behaviour - maintain pregnancy
65
what is the action of testosterone in females?
- substrate for estrogen synthesis - abnormal masculinization
66
what is the action of PGE2 in females?
- ovulation - CL production of progesterone
67
what is the action of hCG in females?
- increase CL progesterone
68
what is the action of eCG in females?
- formation of accessory CL
69
what is the action of placental lactogen in females?
- mammary stimulation