Week 12: Adult Mental Health Flashcards
(77 cards)
Depression screening in adults
- screen ALL adults every visit, including pregnant and postpartum women
- PHQ-2
- PHQ-9 (older adults, cog impaired adults, nursing home residents)
- used as f/u after phq2
- higher S&S
- diagnostic & can give severity of depression
- used as f/u after phq2
- PHQ-9 (older adults, cog impaired adults, nursing home residents)
- geriatric depression scale
- Beck Depression inventory
- Edinburgh postnatal depression scale
Depression labs
- get TSH
- CBC
- UA (drug screening)
- fasting blood glucose
- B12
- folate
MDD assessment
- get baseline PHQ9 Hx, PE
- mental status exam
- suicide risk (thoughts of hurting, SI, plan?)
MDD management
- #1: Safety! Assess ALL for suicidal ideation
- r/o other conditions that can cause depression
- mild depression → psychosocial and psychotherapy (no meds)
- CBT
- interpersonal therapy (IPT)
- problem solving therapy (PST)
- moderate/severe → meds + therapy
MDD pharm management
- moderate-severe depression:
- 1st line: SSRI (sertraline), SNRI, bupropion, mirtazapine
- start low dose for 1-2 wks before dose increase. monitor for suicidal ideation, efficacy and ADE
- educate it takes few weeks for meds to work
- need to continue meds for 6-9months+
SSRI antidepressants list
- SSRI [energizing to least energizing]
- fluoxetine (Prozac)
- sertraline (Zoloft)
- citalopram (Celexa)
- escitalopram (Lexapro)
- causes QT prolongation
- paroxetine (Paxil)
- causes weight gain
- most sedating
SNRI antidepressants and side effects
- increases norepinephrine and serotonin to improve motivation/focus AND mood
- venlafaxine (Effexor)
- desvenlafaxine (Prestiq)
- duloxetine (Cymbalta)
- atomoxetine (Straterra)
bupropion (Wellbutrin)
- good choice antidepressant if don’t have anxiety and have nicotine addiction
- lower risk of decreased libido
antidepressants may induce
- mania in susceptible pts
- black box warning of increased risk of suicidal thoughts/behavior in young people
which antidepressant for pt with anxiety?
- want less energizing
- venlafaxine or duloxetine
- NO bupropion (Wellbutrin)
which antidepressants to avoid with pt’s with cardiac conditions?
- TCA’s (-triptyline) [high risk of cardiac arrhythmia, no in older adults)
- citalopram (Celexa) & escitalopram (Lexapro) [QT prolongation]
pt has depression and ADHD, give what med?
bupropion or venlafaxine
avoid which antidepressant for severe renal/GI issues and seizure?
NO bupropion (lowers seizure threshold)
antidepressant treatment duration
- initial improvement in 1-2 wks, max in 4-12 weeks
- If no response in 4-8 weeks, switch to different antidepressant w/in diff or same class
- after remission of sx’s, continue for 4-9 months
- if 1-2 episodes, can titrate off but if 2 eps, give 1 yr to titrate off. if 3 eps, need continuous maintenance therapy
- OLDER adults takes 12-16 weeks for relief of sx’s (slower process)
fluoxetine pearls
- least likely to gain weight
- most activating
- long half life
- for adolescents and non compliance
- don’t take at night
paroxetine pearls
- interacts with a lot of other meds
- bad withdrawal
- weight gain
- sedating, good for insomnia pts
citalopram pearls
- black box warning QTc prolongation
- NO with CVD dz
- (max dose 40mg QD, 20 mg QD if > 60 yrs old)
escitalopram pearls
weight neutral
neither sedating or activating
qt prolongation
venlafaxine (Effexor) and desvenlafaxine (Pristiq), want to monitor?
monitor HR and BP
induces hypertensive crisis
mirtazapine pearls
- low doses = sedation/drowsiness (15mg, 0.5 tab at half strength) = improves sleep
- if higher dose, sedative factor diminishes
- improves appetite, for pts who are not eating and causes weight gain
when to refer pts with depression?
- EMERGENT/inpatient if:
- immediate risk of self or others
- profound impaired/acutely suffering
- sx’s serotonin syndrome or withdrawal, neuroleptic malignant syndrome or lithium toxicity
- urgent psych w/in 1 week if
- high suicide risk but currently safe
- psych comorbidities
- indications for ECT
- f/u psych w/in 1 month if…
- recurrent sx’s not responding
- complication with med management that requires frequent f/u
- a/s with dementia
- psychotherapy, fam education or group support
depression presents with what
headache, back pain, chronic pain, “tired all the time”
MDD dx in adults
- SIGECAPS: 5 or more sx’s (1 must be depressed mood or lost of interest/pleasure) for 2 weeks:
- sleep (insomnia)
- interest loss
- guilt (worthlessness)
- energy low/fatigue
- concentration (diminished ability)
- appetite (weight gain or anorexia)
- psychomotor agitation/irritation
- suicidal/death thoughts
can’t be due to drug or medical condition (hypothyroidism)
which antidepressant good for sleep aid?
paroxetine, trazodone (Desryl), TCAs