Week 2 Flashcards

(33 cards)

1
Q

Define mood and affect

A

Mood = subjective feeling of sustained emotion (happy, sad)

Affect = objective immediate conveyance of emotion (blunt, flat, labile)

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2
Q

What is the neurochemical theory of depressions cause?

A

Thought to be due to low serotonin, noradrenaline, and dopamine

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3
Q

What is kindling theory in depression?

A

One episode of depression primes the brain for more with less stressful triggers

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4
Q

What are the main clinical features of depression?

A
  • decreased mood
  • anhedonia
    Everyday for more than 2 weeks
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5
Q

What are the biological symptoms of depression?

A
  • Fatigue
  • sleep disturbance
  • loss of appetite
  • weight loss
  • lowered libido
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6
Q

What are the cognitive symptoms of depression?

A
  • lowered concentration
  • negative thoughts
  • guilt
  • hopelessness
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7
Q

What are the psychotic symptoms of depression?

A
  • delusions
  • cotards syndrome
  • hallucinations
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8
Q

What is agitated depression?

A

Usual depressive symptoms but highly restless, often agitated, pacing, psychotic

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9
Q

What is catatonic depression?

A

Severe depression leading to a state of stupor and inhibited motor activity.

Often life threatening as patients stop eating/drinking

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10
Q

What domains are assessed in the mental state exam?

A
  • Appearance
  • Behaviour
  • Eye contact
  • Speech
  • Mood
  • Thoughts
  • Condition
  • Insight
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11
Q

What is the HADS scale

A

Hospital Anxiety and Depression Scale

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12
Q

What are some organic causes of depression?

A
  • Hypothyroidism
  • Hyperglycaemia
  • B12 deficiency
  • Bushings syndrome
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13
Q

What is atypical depression?

A

Low mood like depression, but other symptoms are reversed. E.g. hypersonic instead of insomnia, increased appetite instead of decreased appetite

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14
Q

What are the 1st, 2nd, and 3rd line antidepressants?

A

1st = SSRIs
2nd = SNRIs
3rd = combination

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15
Q

What is the neuroanatomical aetiology of stress?

A

Chronic stress => neuronal change

This leads to decreased hippocampal volume

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16
Q

What is the neurotransmitter aetiology of anxiety?

A

Increased noradrenaline
Decreased serat9nin
? Decreased dopamine
? Decreased GABA

17
Q

What is the anxiety learning theory?

A

Stimulus + unpleasant emotion = pairing

Avoiding that stimulus = reward = maintenance

18
Q

What are the core types of anxiety?

A
  • specific phobias
  • Generalized anxiety disorder
  • panic disorder
19
Q

What are some anxiety associated disorders?

20
Q

Define phobias

A

Excessive anxiety brought on by defined situation, avoided with dread

21
Q

Overview of generalised anxiety disorder

A

Excessive worry, not situational, everyday for 6 months

22
Q

Clinical features of generalized anxiety disorders

A
  • restless
  • fatigued
  • poor concentration
  • irritability
  • tension
  • avoidance
23
Q

Define panic attacks

A

Rapid interest fear with autonomic/physical symptoms

24
Q

Define panic disorder

A

Recurrent panic attacks over a month (can exist by itself but usually associated with other anxiety dissorders)

25
Define obsessions and compulsions
Obsession = repeated intrusive ideas, images, impulses Compulsions = Steteotyped ritualistic behaviours to combat obsessions
26
Define dissociation
Loss of normal integration of memories, identity, sensation
27
Define somatoform disorders
2yr complaints of physical symptoms with no sufficient cause. Causes imparted functioning
28
Mechanism of action for anti anxiety drugs?
Increase noradrenaline and serotonin
29
What are the 1st, 2nd, and 3rd line medications for anxiety?
1st = SSRIs 2nd = SNRIs 3rd = Gabapentinoid
30
What is the MOA of pregabalin
Inhibits calcium channel, therefore has a GABA like effect on amygdala
31
What is the MOA of benzofiazapeines (for anxiety?)
GABA agonist, therefore inhibits the amygdala
32
What mnemonic can you remember to remember the domains of the mental state exam?
A Big Smart Monkey Ate Ten Pinapples, Chewing In Rythm - Appearance - Behaviour - Speech - Mood - Affect - Thoughts - Perception - Cognition - Insight - Risk
33