Week 2-5 Flashcards

Question

RBC

Answer 1

aka erythrocyte

Answer 2

▪ Transports and protects hemoglobin (which carries oxygen to tissues) ▪ Homeostasis – water and electrolytes ▪ Antibody protection ▪ Temperature regulation ▪ Buffering system ▪ Hemostasis

Answer 3

7.0 microns Biconcave disc with central pallor

Answer 4

5.8 microns Biconcave disc with no central pallor (due to small size)

Answer 5

4.5 microns Biconcave disc with no central pallor

Answer 6

3.2 microns Biconcave disc with no cental pallor

Answer 7

Canine -> Feline/Equine/Bovine -> Sheep -> Goat

Answer 8

Rubriblast Prorubricyte Rubricyte Metarubricyte Polychromatic RBC Erythrocyte

Answer 9

Large, perfectly round cell with large, round nucleus and royal blue cytoplasm Light blue nucleoli Nuclear chromatin is stippled Perinuclear clear area

Answer 10

Similar to rubriblast but smaller No nucleoli present Round nucleus Chromatin more coarse (hard to tell) Royal blue cytoplasm Perinuclear clear zone

Answer 11

Nuclear chromatin (spoked wheel pattern) Nucleus is round and dark purple with blue black chromatin Cytoplasm dark blue; lightens to pink as hemoglobin increases Divided into basophilic, polychromatic or normochromatic as presence of hemoglobin increases

Answer 12

Nucleus undergoes a pyknotic degeneration (shrinking, dense) Appears as dark blue mass with no distinct chromatin structure Cytoplasm is pink (due to hemoglobin) with a basophilic hue When seen in peripheral blood they are called nucleated RBCs

Answer 13

Anucleate erythrocyte with slight basophilia Larger than mature RBCs When stained with new methylene blue, some show a network of blue fibers - RNA - Cells are called reticulocytes

Answer 14

Mature RBC in peripheral blood Stain pink

Answer 15

Stacked like coins

Answer 16

No uniform size

Answer 17

Larger size

Answer 18

Normal sized RBCs

Answer 19

Smaller than usual

Answer 20

Decreased staining caused by reduced hemoglobin Most often are microcytes Decreased MCV (mean corpuscle value)

Answer 21

Does not exist because each RBC has a limit of hemoglobin it can carry

Answer 22

Polychromatophilic RBC These are reticulocytes when stained with new methylene blue

Answer 23

General term describing abnormally shaped RBCs

Answer 24

RBC fragments Torn RBC

Answer 25

Formed by intravascular trauma and mechanical injury which resulting in turbulent blood flow

Answer 26

Irregular blunt projection cells Few, unevenly distributed projections Variable length and diameter

Answer 27

Due to alternations in lipid composition of the RBCs Seen in hepatic diseases From cholesterol changes at cell membrane Seen in hemangiosarcoma (acanthocytes considered a blood biomarker for this condition)

Answer 28

Numerous short, evenly spaced blunt to sharp projections of uniform shape and size

Answer 29

Can be due to renal disease or an electrolyte imbalance but often due to faulty technique - Crenation caused by slow smear drying - Excessive anticoagulant may also cause

Answer 30

Darkly stained cells with reduced or no central pallor Perfectly round sphere, no longer disk shaped Not easily detected in species other than dogs because other species lack central pallor Typically, the volume of cell is normal Normal MCV

Answer 31

Seen in IMHA - macrophage bites the RBC

Answer 32

General term referring to cells with increased membrane surface relative to cell volume - Can result to cell folding Cells take on a variety of shapes Includes target cells and stomatocytes

Answer 33

aka Codocyte Type of leptocyte Bullseye appearance Central rounded area of Hb surrounded by a clear zone with a dense ring of Hb at the periphery

Answer 34

Found in hepatic disorders, iron deficiency and IMHA

Answer 35

Type of leptocyte Cup shaped RBC with an oval, elongated mouth appearing in the central pallor Artifact due to thick blood smear

Answer 36

Non-specific finding seen in: - Hereditary condition in malamutes - Drug-induced - Regenerative anemia - Liver disease - Lead poisoning

Answer 37

Blister on one side of RBC forming an area devoid of hemoglobin

Answer 38

Oxidative injury seen with iron deficiency

Answer 39

Ruptured blister with two upright "cattle horn-like" projections Projections fragment from RBC to form schizocytes

Answer 40

Can be seen in healthy cats with no clear significance Can be seen in DIC, hemangiosarcoma, iron deficiency anemia, liver disease

Answer 41

Tear drop shaped erythrocyte with a single elongated or pointed end

Answer 42

May be found in bone marrow disorders of dogs and cats, iron deficiency in ruminants, kidney and splenic disorders in dogs Result of mechanical fragmentation

Answer 43

Sickle cell RBC changes to a spindle shape - Cell elongates and comes to a sharp or round point on both ends

Answer 44

Result of alteration of hemoglobin due to temperature, oxygen and pH changes (alkalosis) Seen in normal deer, angora goat and some sheep blood

Answer 45

Red at one end and clear at the other end giving a half moon appearance

Answer 46

Due to excess oxidant stress Found in hemolytic diseases seen in dogs with onion/acetaminophen ingestion Often see heinz bodies with them

Answer 47

Ovalocyte (previous name) Oval or elliptical RBC More flat than concave

Answer 48

Can be non-specific or due to smear making technique May be seen in iron deficiency anemia or liver disease

Answer 49

Extremely pale to colourless Appearing round to smudge-like Devoid of hemoglobin in the cytoplasmW

Answer 50

Can be due to intravascular hemolysis or blood film preparation

Answer 51

Punched out cell Abrupt change from dense red to white area giving a "punched out" apprearance

Answer 52

Artifact of improper spreading of blood on slide

Week 2-5 Flashcards

(78 cards)