Week 2 Flashcards

(39 cards)

1
Q

What are the 4 main types of Ions?

A

Sodium
Potassium
Chloride
Organic Anions

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2
Q

What does Cl- stand for?

A

Chloride (Cl-)

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3
Q

What does Na+ stand for?

A

Sodium (Na+)

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4
Q

During the resting state, is a neuron pos or neg charged?

A

Negatively

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5
Q

What does K+ stand for?

A

Potassium (K+)

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6
Q

As an atom positively or neg charged?

A

no, it’s neutral. When it stops being neutral it becomes and Ion (pos OR neg charged)

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7
Q

What does A- Stand for?

A

Organic Anions (A-)

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8
Q

What is the shorthand for Sodium?

A

Na+

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9
Q

What is the shorthand for potassium?

A

K+

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10
Q

What is an Ion?

A

pos or neg charged Atom

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11
Q

What is shorthand for Organic Anions?

A

A-

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12
Q

What is shorthand for Chloride?

A

Cl-

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13
Q

Where do the pos & negative electrons and protons sit in an atom?

A

Positive Protons inside nucleus

Neg Electron orbit around nucleus in outer shell

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14
Q

Is an electron pos or neg?

A

neg

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15
Q

is a proton pos or neg?

A

pos

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16
Q

Is an atom pos or neg charged?

A

Neither, it’s neutral - pos & neg even each other out so in resting state it remains neutral

17
Q

what is an ion?

A

pos or neg charged atom

18
Q

how does an ion become negatively charged?

A

gaines neg electron

19
Q

How is the resting potential maintained?

A

Ion channels

allows inflow of ions in and out of cell

Sodium-Potassium pump

20
Q

Where are receptors found?

A

Mostly Cell Body & Dendrites

21
Q

In analogy of lock and key, receptors are one and key is the other. Which is the Receptor?

A

Receptor is key

22
Q

What do autoreceptors do?

A

Turn off neurotransmitter release (stimulated neurotransmitters released by own neuron)

23
Q

What is the GABBA-A neurotransmitter?

A

Main inhibitory

24
Q

What is an Antagonist?

A

A drug that opposes or inhibits the effects of a particular neurotransmitter on the postsynaptic cell

25
What is an Agonist?
A drug that facilitates the effects of a particular neurotransmitter on the postsynaptic cell
26
Which drug action imitates a neurotransmitter?
Agonist
27
What is a direct antagonist?
A drug that binds with receptor but does not activate it - prevents the natural ligand from binding with the receptor. Stops natural action
28
what is a direct agonist?
A drug that binds with and activated receptor - just as the neurotransmitter would
29
What is non-competitive binding on a receptor?
Binding of a drug to a site on a receptor; does not interfere with the binding site for the principal ligand.
30
What is an indirect agoinst?
A drug that attaches to a binding site on a receptor and facilitates the action of the receptor; does not interfere with the binding site of the principal ligand.
31
What is an indirect antagonist?
A drug that attaches to a binding site on a receptor and interferes with the action of the receptor; does not interfere with the binding of the principal ligand.
32
What is a resting membrane potential?
resting potential
33
How does an atom become a neg charged ion?
gains a negative charged electron
34
how doe an atom become a pos charged ion?
looses a neg charged electron
35
what is a excitatory postsynaptic potential (EPSP)?
if stimulations causes the voltage inside of the cell to become more positive (keep firing)
36
what is a Inhibitory postsynaptic potential (IPSP)?
if stimulations causes the voltage inside of the cell to become more negative (stop firing)
37
neurotransmitters cant be left in the gap as they will continue to exert effect or block receptor. What is the Reuptake pump?
physical removal of neurotransmitter - directs it back into presynaptic neuron for recycling
38
neurotransmitters cant be left in the gap as they will continue to exert effect or block receptor. What is an Exzymatic degredation?
Enzymes break down neurotransmitters no longer fire
39
Where are receptors mostly found?
dendrites & cell body