Week 2 Flashcards

(43 cards)

1
Q

Is the heat response vasoconstriction or vasodilation?

A

Vasodilatoin

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2
Q

Is the cold response vasoconstriction or vasodilation?

A

Vasoconstriction; decreased sweating, shivering

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3
Q

What skin disorder is caused by Chediak-Higashi Syndrome?

A

Albinism (tyrosine mutation)

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4
Q

Pemphigus Vulgaris: IgG autoantibodies against ____

A

Desmoglein 3

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5
Q

Where does fluid accumulate in pemphigus vulgaris?

A

Above basal layer

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6
Q

Bullous Pemphiogoid: IgG autoantibodies against _____

A

Hemidesmosomes

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7
Q

Where does fluid accumulate in Bullous Pemphigoid?

A

Between epidermis and basement membrane

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8
Q

Nikolsky sign is positive in ___ and negative in ____.

A

P. vulgaris; b. pemphigoid

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9
Q

Which skin disorder is associated with celiac disease?

A

Dermatitis Herpetiformis

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10
Q

Guarnieri bodies are associated with _____.

A

Smallpox (variola)

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11
Q

A “pearl-like” skin lesion is most likely referring to which disease?

A

Molluscum contagiosum

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12
Q

What are Tzanck smears used for?

A

Diagnosing active herpes infection

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13
Q

Fifth Disease is associated with ______

A

Parvo B19 virus

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14
Q

Which disease is this: after fever, rash starts on trunks then spreads to extremities

A

Roseola

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15
Q

Hand, foot, and mouth disease is caused by which virus

A

Cocksackievirus (Picornavirus – enterovirus (naked +ssRNA)

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16
Q

A rash commonly appears on hands and soles of feet in ______.

A

Treponema Pallidum

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17
Q
Name the disease: Centripetal rash -appears first on
the wrists and ankles, often
spreading within hours
proximally to the trunk and
distally to the palms and soles
A

Rocky Mountain Spotted Fever

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18
Q

What is the most common cervical radiculopathy?

A

C7 radiculopathy

19
Q

C4 dermatome:

A

skin over the shoulder tip

20
Q

C5 dermatome:

A

upper lateral arm

21
Q

C6 dermatome:

22
Q

C7 dermatome:

23
Q

C8 dermatome:

A

little finger

24
Q

T1 dermatome

25
T2 dermatome
skin of axilla
26
C5 myotome:
shoulder abduction
27
C6 myotome:
elbox flexion
28
C7 myotome:
elbow extension
29
C8 myotome:
flexion of fingers
30
T1 myotome:
abduction and adduction of fingers
31
what are the terminal branches of the brachial plexus?
Musculocutaneous nerve, axillary nerve, radial nerve, median nerve, ulnar nerve
32
Describe Erb-Duchenne paralysis (waiter's tip)
adducted shoulder, extended elbow, internally rotated arm)
33
which nerves are affected in Erb-Duchenne paralysis?
axillary (deltoid abduction), musculocutaneous (biceps flexion), suprascapular nerve (infraspinatus external rotation)
34
which nerves are involved in Klumpke paralysis?
radial and ulnar
35
In Pemphigus Vulgaris, Abs are directed against _______.
Desmoglein 3
36
In Kawasaki Disease, Abs are directed against _____.
Blood vessels
37
In immune-mediated thrombocytopenia, Abs are directed against
platelets.
38
Kawaski disease most commonly occurs after _____ in _____ children.
infection; genetically disposed
39
Serum sickness: deposition of immune complexes in _____.
tissue
40
Arthus reaction: deposition of immune complexes in ______.
skin
41
morbiliform rash on the face is likely due to _____
Steven Johnsons
42
morbiliform rash on the trunk is likely due to ______
DRESS syndrome
43
white dots or lines known as Wickham striae are seen in which condition?
lichen planus