Week 2-Respiratory System Flashcards
(74 cards)
What is the primary purpose of the respiratory system?
Gas exchange – providing oxygen to the body and removing carbon dioxide.
Define ventilation in respiratory physiology.
Ventilation is the movement of air in and out of the lungs, driven by pressure changes caused by the diaphragm and intercostal muscles.
What is perfusion in the respiratory system?
Perfusion refers to blood flow through the pulmonary capillaries to facilitate gas exchange.
What does diffusion refer to in the lungs?
Diffusion is the movement of gases (O₂ and CO₂) across the alveolar-capillary membrane based on concentration gradients.
Describe the role of pulmonary circulation in gas exchange.
It transports deoxygenated blood from the heart to the lungs and returns oxygenated blood back to the heart for systemic circulation.
What is the pathophysiology of asthma?
Asthma involves chronic airway inflammation, hyperresponsiveness, and mucus hypersecretion, leading to reversible airway obstruction.
What are common symptoms of asthma?
Wheezing, shortness of breath, chest tightness, coughing, and tachycardia.
What inflammatory mediators are released during an asthma attack?
Histamine, interleukins, prostaglandins, leukotrienes, and nitric oxide.
What is the pathophysiology of COPD?
COPD includes chronic bronchitis and emphysema (air sacs are damaged), leading to inflammation, alveolar damage, mucus buildup, and airflow obstruction.
What are key symptoms of COPD?
chronic cough, sputum production, breathlessness, wheezing, and chest tightness.
What causes air trapping in COPD?
Loss of alveolar elasticity impairs expiration, trapping air in the lungs and causing hyperinflation.
What is pneumonia?
Pneumonia is an infection that inflames the alveoli, filling them with fluid or pus and impairing gas exchange
What are the clinical signs of pneumonia?
Fever, chills, cough with sputum, dyspnoea(Laboured breathing), chest pain, fatigue, and low SpO₂.
What are the four main components of a respiratory assessment?
Inspection, palpation, percussion, and auscultation.
What is observed during respiratory inspection?
Breathing rate, rhythm, effort, chest movement, and skin colour.
What is palpation used for in respiratory assessment?
To assess chest expansion and tactile fremitus (vibrations).
What does percussion tell you during respiratory assessment?
It helps identify areas of lung consolidation, air, or fluid by changes in sound.
What do wheezes and crackles indicate?
Wheezes suggest narrowed airways (e.g., asthma), while crackles suggest fluid (e.g., pneumonia).
What are SABAs and their role?
Short-acting beta2-agonists provide quick relief from bronchospasm. Example: Salbutamol.
Name some long-acting beta2-agonists (LABAs).
Salmeterol, Formoterol, and Indacaterol.
What are anticholinergics used for in respiratory care?
To relax airway muscles and decrease mucus. E.g., Ipratropium (short-acting), Tiotropium (long-acting).
Name corticosteroids used for inflammation in asthma and COPD.
Prednisolone, Hydrocortisone, Methylprednisolone, Dexamethasone.
What are mast cell stabilisers used for?
Maintenance treatment of asthma and COPD. E.g., Cromoglycate, Lodoxamide.
Which antibiotics are commonly used for respiratory infections?
Penicillins, cephalosporins, and tetracyclines.