Week 3- Diabetes Flashcards
(124 cards)
1
Q
Canagliflozin Brand name
A
Invokana
2
Q
Canagliflozin Class
A
SGLT-2i
3
Q
Canagliflozin Dosage forms
A
Oral tablet
4
Q
Canagliflozin Indication
A
T2DM
5
Q
Canagliflozin BBW
A
Amputation of lower limbs
6
Q
Canagliflozin CI’s
A
Severe renal impairment
7
Q
Canagliflozin Dose Adjustments
A
Renal
8
Q
Canagliflozin SE (3)
A
Hyperkalemia
GU infection
Renal insufficiency
9
Q
Dapagliflozin Brand Name
A
Farxiga
10
Q
Dapagliflozin Class
A
SLGT-2i
11
Q
Dapagliflozin dosage forms
A
Oral tablet
12
Q
Dapagliflozin Indication
A
T2DM
HF
13
Q
Dapagliflozin dose adjustments
A
Renal
14
Q
Dapagliflozin CI
A
Severe renal impairment
15
Q
Dapagliflozin SE
A
No significant
16
Q
Dulaglutide Brand name
A
Trulicity
17
Q
Dulaglutide Class
A
GLP-1
18
Q
Dulaglutide MOA
A
glucose-dependent insulin secretion and slows gastric emptying
19
Q
Dulaglutide indication
A
T2DM
20
Q
Dulaglutide BBW
A
Risk of thyroid cancers
21
Q
Dulaglutide CI
A
Family H/O medullary thyroid carcinoma
22
Q
Dulaglutide dosage form
A
Pen injector, SC
23
Q
Dulaglutide SE (3)
A
Nausea
Diarrhea
Weight loss
24
Q
Dulaglutide Max dose
A
4.5 mg once weekly
25
Exenatide Brand name
Byetta
Bydureon
26
Exenatide class
GLP-1
27
Exenatide dosage forms
SC Solution for injection
SC Suspension for injection
28
Exenatide indication
T2DM
29
Exenatide MOA
Glucose dependent insulin secretion and slows gastric emptying
30
Exenatide dose adjustments
Renal
31
Exenatide BBW
Thyroid C- cell tumors (bydureon)
32
Exenatide SE (4)
Hypoglycemia
Nausea
Diarrhea
Injection site reaction
33
Liraglutide Brand name
Victoza
Saxenda
34
Liraglutide drug class
GLP-1
35
Liraglutide dosage forms
Solution, pen injector
36
Liraglutide MOA
increases glucose-dependent insulin secretion, decreases inappropriate glucagon secretion, slows gastric emptying, and increases satiety.
37
Liraglutide Indication
T2DM
Weight loss
38
Liraglutide BBW
Increased risk of thyroid cancer
39
Liraglutide CI
multiple endocrine neoplasia syndrome type 2
family history of medullary thyroid carcinoma
40
Liraglutide SE (4)
Nausea
Diarrhea
Vomiting
Hypoglycemia
41
Liraglutide max dose (victoza)
1.8 mg/day
42
Glimepiride Brand name
Amaryl
43
Glimepiride Class
2nd gen sulfonylurea
44
Glimepiride dosage forms
Oral tablet
45
Glimepiride Indication
T2DM
46
Glimepiride max dose
8 mg/day
47
Glimepiride MOA
Enhances insulin secretion from pancreatic beta cells
48
Glimepiride dose adjustments
Renal
49
Glimepiride CI
Diabetic Ketoacidosis
50
Glimepiride SE
No significant SE
51
Glipizide Brand name
Glucotrol
52
Glipizide Class
2nd gen sulfonyl urea
53
Glipizide dosage forms
Oral tablet
54
Glipizide MOA
Enhance insulin secretion from pancreatic beta cells
55
Glipizide Indications
DM
56
Glipizide max dose
40 mg/ day (IR)
20 mg/day (ER)
57
Glipizide dose adjustments
Hepatic
Renal
58
Glipizide CI
Diabetic Ketoacidosis
T1DM
59
Glipizide SE
Asthenia
60
Linagliptin brand name
Tradjenta
61
Linagliptin class
DPP-4
62
Linagliptin dosage forms
Oral tablet
63
Linagliptin indication
T2DM
64
Linagliptin MOA
Inhibits DPP-4 enzyme leading to prolonged incretin hormones (GLP/GIP)
65
Linagliptin SE
Hypoglycemia
66
Saxagliptin brand name
Onglyza
67
Saxagliptin class
DPP-4 inhibitor
68
Saxagliptin dosage forms
Oral tablet
69
Saxagliptin indication
DM
70
Saxagliptin MOA
Inhibits DPP-4 enzyme and enhances functions of GLP/GIP
71
Saxagliptin dose adjustments
Renal
72
Saxagliptin SE
Hypoglycemia
73
Sitagliptin Brand name
Januvia
74
Sitagliptin class
DPP-4 inhibitor
75
Sitagliptin dosage forms
Oral tablet
76
Sitagliptin inidication
T2DM
77
Sitagliptin MOA
Inhibits DPP-4 enzyme and enhances functions of GLP/GIP
78
Sitagliptin dose adjustments
Renal
79
Sitagliptin SE
Hypoglycemia
80
Metformin brand name
Glucophage
81
Metformin class
Biguanide
82
Metformin dosage forms
Oral tablet
Oral solution
83
Metformin Indiciations
T2DM
PCOS
84
Metformin MOA
Reduces hepatic glucose production & enhances glucose utilization by muscle
85
Metformin dose adjustments
Renal
86
Metformin BBW
Lactic acidosis
87
Metformin CI
eGFR <30
Metabolic acidosis
88
Metformin SE (6)
GI: nausea, vomiting, diarrhea, flatulence
Malabsorption
Asthenia
89
Lantus generic name
Insulin glargine
90
Lantus class
Insulin LA
91
Lantus indication
DM
92
Lantus dosage forms
Solution, SC
Solution pen injector, SC
93
Lantus MOA
Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue
94
Lantus dose adjustments
Renal
95
Lantus CI
Hypokalemia
96
Lantus SE (7)
Hypertension
Peripheral edema
Hypoglycemia
Diarrhea
UTI
Infections
Depression
97
Levemir Generic name
Detemir
98
Levemir class
Insulin LA
99
Levemir dosage forms
Solution, SC
Solution pen injector, SC
100
Levemir indications
DM
101
Levemir MOA
Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue
102
Levemir CI
HYPOkalemia
103
Levemir SE
Hypoglycemia
Abdominal pain
Headache
Flu like symptoms
Upper respiratory tract infection
104
Novolog generic name
Insulin aspart
105
Novolog class
Insulin , RA
106
Novolog dosage forms
Solution, injection
Solution pen injector, SC
107
Novolog MOA
Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue
108
Novolog indication
DM
109
Novolog CI
HYPOkalemia
110
Novolog SE
Hypoglycemia
Headache
Nasopharyngitis
111
Humalog generic name
Lispro
112
Humalog class
Insulin, RA
113
Humalog dosage forms
Solution, SC
Solution pen- injector, SC
114
Humalog indications
DM
115
Humalog MOA
Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue
116
Humalog CI
HYPOkalemia
117
Humalog SE
Hypoglycemia
Headache
Pain
Cough
Flu like symptoms
118
Garlic brand name
Allium
Alho
119
Garlic class
Antihyperlipidemic
120
Garlic dosage form
Capsule
121
Garlic indications
Hyperlipidemia
Hypertension
122
Garlic MOA
Allicin is thought to be the active ingredient of garlic and has antioxidant and antilipid properties, although the precise mechanism is unknown
123
Garlic CI
Surgery (discontinue 10 days prior to elective surgery)
124
Garlic SE
Offensive odor
Nausea
