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Top 200 Drug Quizzes > Week 3- Diabetes > Flashcards

Week 3- Diabetes Flashcards

1
Q

Canagliflozin Brand name

A

Invokana

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2
Q

Canagliflozin Class

A

SGLT-2i

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3
Q

Canagliflozin Dosage forms

A

Oral tablet

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4
Q

Canagliflozin Indication

A

T2DM

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5
Q

Canagliflozin BBW

A

Amputation of lower limbs

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6
Q

Canagliflozin CI’s

A

Severe renal impairment

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7
Q

Canagliflozin Dose Adjustments

A

Renal

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8
Q

Canagliflozin SE (3)

A

Hyperkalemia
GU infection
Renal insufficiency

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9
Q

Dapagliflozin Brand Name

A

Farxiga

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10
Q

Dapagliflozin Class

A

SLGT-2i

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11
Q

Dapagliflozin dosage forms

A

Oral tablet

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12
Q

Dapagliflozin Indication

A

T2DM
HF

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13
Q

Dapagliflozin dose adjustments

A

Renal

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14
Q

Dapagliflozin CI

A

Severe renal impairment

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15
Q

Dapagliflozin SE

A

No significant

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16
Q

Dulaglutide Brand name

A

Trulicity

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17
Q

Dulaglutide Class

A

GLP-1

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18
Q

Dulaglutide MOA

A

glucose-dependent insulin secretion and slows gastric emptying

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19
Q

Dulaglutide indication

A

T2DM

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20
Q

Dulaglutide BBW

A

Risk of thyroid cancers

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21
Q

Dulaglutide CI

A

Family H/O medullary thyroid carcinoma

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22
Q

Dulaglutide dosage form

A

Pen injector, SC

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23
Q

Dulaglutide SE (3)

A

Nausea
Diarrhea
Weight loss

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24
Q

Dulaglutide Max dose

A

4.5 mg once weekly

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25
Q

Exenatide Brand name

A

Byetta
Bydureon

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26
Q

Exenatide class

A

GLP-1

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27
Q

Exenatide dosage forms

A

SC Solution for injection
SC Suspension for injection

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28
Q

Exenatide indication

A

T2DM

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29
Q

Exenatide MOA

A

Glucose dependent insulin secretion and slows gastric emptying

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30
Q

Exenatide dose adjustments

A

Renal

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31
Q

Exenatide BBW

A

Thyroid C- cell tumors (bydureon)

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32
Q

Exenatide SE (4)

A

Hypoglycemia
Nausea
Diarrhea
Injection site reaction

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33
Q

Liraglutide Brand name

A

Victoza
Saxenda

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34
Q

Liraglutide drug class

A

GLP-1

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35
Q

Liraglutide dosage forms

A

Solution, pen injector

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36
Q

Liraglutide MOA

A

increases glucose-dependent insulin secretion, decreases inappropriate glucagon secretion, slows gastric emptying, and increases satiety.

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37
Q

Liraglutide Indication

A

T2DM
Weight loss

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38
Q

Liraglutide BBW

A

Increased risk of thyroid cancer

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39
Q

Liraglutide CI

A

multiple endocrine neoplasia syndrome type 2
family history of medullary thyroid carcinoma

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40
Q

Liraglutide SE (4)

A

Nausea
Diarrhea
Vomiting
Hypoglycemia

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41
Q

Liraglutide max dose (victoza)

A

1.8 mg/day

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42
Q

Glimepiride Brand name

A

Amaryl

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43
Q

Glimepiride Class

A

2nd gen sulfonylurea

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44
Q

Glimepiride dosage forms

A

Oral tablet

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45
Q

Glimepiride Indication

A

T2DM

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46
Q

Glimepiride max dose

A

8 mg/day

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47
Q

Glimepiride MOA

A

Enhances insulin secretion from pancreatic beta cells

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48
Q

Glimepiride dose adjustments

A

Renal

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49
Q

Glimepiride CI

A

Diabetic Ketoacidosis

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50
Q

Glimepiride SE

A

No significant SE

51
Q

Glipizide Brand name

A

Glucotrol

52
Q

Glipizide Class

A

2nd gen sulfonyl urea

53
Q

Glipizide dosage forms

A

Oral tablet

54
Q

Glipizide MOA

A

Enhance insulin secretion from pancreatic beta cells

55
Q

Glipizide Indications

A

DM

56
Q

Glipizide max dose

A

40 mg/ day (IR)
20 mg/day (ER)

57
Q

Glipizide dose adjustments

A

Hepatic
Renal

58
Q

Glipizide CI

A

Diabetic Ketoacidosis
T1DM

59
Q

Glipizide SE

A

Asthenia

60
Q

Linagliptin brand name

A

Tradjenta

61
Q

Linagliptin class

A

DPP-4

62
Q

Linagliptin dosage forms

A

Oral tablet

63
Q

Linagliptin indication

A

T2DM

64
Q

Linagliptin MOA

A

Inhibits DPP-4 enzyme leading to prolonged incretin hormones (GLP/GIP)

65
Q

Linagliptin SE

A

Hypoglycemia

66
Q

Saxagliptin brand name

A

Onglyza

67
Q

Saxagliptin class

A

DPP-4 inhibitor

68
Q

Saxagliptin dosage forms

A

Oral tablet

69
Q

Saxagliptin indication

A

DM

70
Q

Saxagliptin MOA

A

Inhibits DPP-4 enzyme and enhances functions of GLP/GIP

71
Q

Saxagliptin dose adjustments

A

Renal

72
Q

Saxagliptin SE

A

Hypoglycemia

73
Q

Sitagliptin Brand name

A

Januvia

74
Q

Sitagliptin class

A

DPP-4 inhibitor

75
Q

Sitagliptin dosage forms

A

Oral tablet

76
Q

Sitagliptin inidication

A

T2DM

77
Q

Sitagliptin MOA

A

Inhibits DPP-4 enzyme and enhances functions of GLP/GIP

78
Q

Sitagliptin dose adjustments

A

Renal

79
Q

Sitagliptin SE

A

Hypoglycemia

80
Q

Metformin brand name

A

Glucophage

81
Q

Metformin class

A

Biguanide

82
Q

Metformin dosage forms

A

Oral tablet
Oral solution

83
Q

Metformin Indiciations

A

T2DM
PCOS

84
Q

Metformin MOA

A

Reduces hepatic glucose production & enhances glucose utilization by muscle

85
Q

Metformin dose adjustments

A

Renal

86
Q

Metformin BBW

A

Lactic acidosis

87
Q

Metformin CI

A

eGFR <30
Metabolic acidosis

88
Q

Metformin SE (6)

A

GI: nausea, vomiting, diarrhea, flatulence
Malabsorption
Asthenia

89
Q

Lantus generic name

A

Insulin glargine

90
Q

Lantus class

A

Insulin LA

91
Q

Lantus indication

A

DM

92
Q

Lantus dosage forms

A

Solution, SC
Solution pen injector, SC

93
Q

Lantus MOA

A

Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue

94
Q

Lantus dose adjustments

A

Renal

95
Q

Lantus CI

A

Hypokalemia

96
Q

Lantus SE (7)

A

Hypertension
Peripheral edema
Hypoglycemia
Diarrhea
UTI
Infections
Depression

97
Q

Levemir Generic name

A

Detemir

98
Q

Levemir class

A

Insulin LA

99
Q

Levemir dosage forms

A

Solution, SC
Solution pen injector, SC

100
Q

Levemir indications

A

DM

101
Q

Levemir MOA

A

Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue

102
Q

Levemir CI

A

HYPOkalemia

103
Q

Levemir SE

A

Hypoglycemia
Abdominal pain
Headache
Flu like symptoms
Upper respiratory tract infection

104
Q

Novolog generic name

A

Insulin aspart

105
Q

Novolog class

A

Insulin , RA

106
Q

Novolog dosage forms

A

Solution, injection
Solution pen injector, SC

107
Q

Novolog MOA

A

Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue

108
Q

Novolog indication

A

DM

109
Q

Novolog CI

A

HYPOkalemia

110
Q

Novolog SE

A

Hypoglycemia
Headache
Nasopharyngitis

111
Q

Humalog generic name

A

Lispro

112
Q

Humalog class

A

Insulin, RA

113
Q

Humalog dosage forms

A

Solution, SC
Solution pen- injector, SC

114
Q

Humalog indications

A

DM

115
Q

Humalog MOA

A

Acts via membrane bound receptors. Targets organs for insulin including liver, muscle, and adipose tissue

116
Q

Humalog CI

A

HYPOkalemia

117
Q

Humalog SE

A

Hypoglycemia
Headache
Pain
Cough
Flu like symptoms

118
Q

Garlic brand name

A

Allium
Alho

119
Q

Garlic class

A

Antihyperlipidemic

120
Q

Garlic dosage form

A

Capsule

121
Q

Garlic indications

A

Hyperlipidemia
Hypertension

122
Q

Garlic MOA

A

Allicin is thought to be the active ingredient of garlic and has antioxidant and antilipid properties, although the precise mechanism is unknown

123
Q

Garlic CI

A

Surgery (discontinue 10 days prior to elective surgery)

124
Q

Garlic SE

A

Offensive odor
Nausea

Top 200 Drug Quizzes (1 decks)

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