Week 4 Hepatitis Flashcards
(53 cards)
What are the most common types of hepatitis in canada
A, B, C
What is hepatomegaly
an enlarged liver
what is the most severe form of Nonalcoholic Fatty Liver Disease and what does this mean
non-alcoholic steatohepatitis (NASH) which means that fatty build up has started to damage liver cells resulting in fibrosis
what is Metabolic dysfunction-associates steatotic liver disease
when fat builds up in the liver and causes inflammation and possibly cirrhosis (previously known as NAFLD)
what are risk factors for MASLD
-Obesity
-Type 2 DM
-increased age
What would it mean if AST was elevated
Indicates that there is inflammation of an organ but not specific to a single organ (the “S” stands for several organs
What would an elevated ALT level indicate
Specifically indicates liver inflammation
What would an elevated GGT level indicate
Indicates Cholecystitis and alcohol induced fatty liver disease (Stands for “Get Me Another Drink”)
What does an elevated ALP level indicate
-Can indicate liver disease (but is not specific to the liver)
-Bone disease (ie bone CA)
What might Albumin Bilirubin and INR levels look like in a patient with liver disease
-Decreased Albumin (since the liver isn’t functioning properly can’t create enough)
-Increased bilirubin (Since the liver excretes bilirubin if it’s not working properly it will build up in the blood)
-Increased INR (since the liver produces platelets if its not functioning properly the blood will take longer to clot)
How is hepatitis A spread
spread via the fecal oral route
If a person had the IgM antibodies to hepatitis A what would that indicate
Would indicate that there is an acute infection going on
if a person had the IgG antibody to hepatitis A what would that indicate
would indicate that the person has had exposure to Hep A in the past either through vaccination or the disease itself and now has immunity
what would it indicate if someone had a negative IgM to hep A but a positive IgG
means they are not experiencing an acute infection but they have been exposed in the past either by vaccination or having the disease in the past
Can Hep A result in a chronic carrier state*
No the disease is self limiting and fully resolves with no lasting effects and people do not remain contagious if they have had the disease
Are there scheduled vaccines for Hepatitis A
No only people who are at high risk receive a vaccine
are there scheduled vaccines for hepatitis B
yes immunizations are scheduled at 2, 4 and 6 months
how is hepatitis B spread
spread via blood and bodily fluids
What does Hepatitis B surface antigen indicate
Indicates that a person currently has hepatitis B (so can be present in an acute or chronic infection just not in a resolved infection)
What does Anti hepatitis B surface antibodies indicate
Means that someone has been exposed either through vaccination or infection and is now immune
What does Total Antibody to Hepatitis B Virus core Antigen indicate
Indicates an acute chronic or resolved infection
what would someones Hepatitis B serology look like if they had a resolved Hep B
-Negative HB Surface AG
-Positive Anti Hep B Surface Antibodies
-Positive Total AB to HBV Core Antigen
what would someones Hep B serology look like if they had a chronic Hep B infection
-Positive HB Surface AG
-Negative Anti Hep B Surface Antibodies (because they still have the infection they did not develop immunity)
-Positive Total AB to HBV Core Antigen
Is there a vaccine for hepatitis C
No there is no Hepatitis C vaccine
