Week 4 Medications Antipsychotics

Question 1

Lithium effective in treatment of

Answer 1

Acute mania
Acute bipolar depression
Prevention of manic and depressive episodes
-Takes 3-6 weeks for a full response

Question 2

Lithium side effects

Answer 2

Fine hand tremors
Polyuria, mild thirst
Nausea
Weight gain
Sedation
Acne

Question 3

Lithium therapeutic level

Answer 3

0.5-1.2 mEq/L

Question 4

Lithium-early signs of toxicity

Answer 4

N/V/D
Slurred speech
Muscle weakness

Question 5

Lithium-advanced signs of toxicity

Answer 5

Coarse hand tremor
GI upset
Mental confusion
Muscle hyperirritability
EEG changes
Incoordination

Question 6

Lithium-severe toxicity

Answer 6

Ataxia
Serious EEG changes
Blurred vision
Clinic movements, seizures
Stupor
Coma
Death

Question 7

Lithium- long term side effects

Answer 7

Hypothyroidism, goiter
Kidney dysfunction

Question 8

Anticonvulsants

Answer 8

Depakote
Divalproex
Valproate
Valproic acid

Question 9

Anticonvulsants- effective in treatment of

Answer 9

Bipolar mania
Hypomania
Mixed states (depression and hypomania at same time)
Rapid cycling

Question 10

Anticonvulsants side effects

Answer 10

GI pain
Tremors
Sedation
Hair loss
Weight gain
Blood dyscrasias
Hepatotoxicity (affects the liver so frequently monitor)
Pancreatitis

Question 11

Anticonvulsants toxicity symptoms

Answer 11

Ataxia
Confusion
Somnolence
Coma

Question 12

Anticonvulsants- Carbamazepine use

Answer 12

Same as above along with Bipolar disorder

Question 13

Carbamazepine side effects

Answer 13

Hepatic disease
Blood dyscrasias
Fluid overload
Hyponatremia
Life-threatening dermatological reactions

decreases effectiveness of birth control pills

Teratogenic

Question 14

Carbamazepine toxicity symptoms

Answer 14

Fatigue, nausea
Diplopia
Blurred vision
Ataxia

Question 15

Anticonvulsants- Lamotrigine

Answer 15

Treatment of:
Bipolar depression : acute and maintenance

Question 16

Lamotrigine side effects

Answer 16

Steven Johnson’s
Aseptic meningitis (monitor for fever)
Can lower effectiveness of birth control

Question 17

Benzodiazepines

Answer 17

Clonazepam
Lorazepam

Question 18

Benzodiazepine uses

Answer 18

Adjunctive agents
Acute mania
Psychomotor agitation

— best for patients who are noncompliant

Question 19

Second-gen antipsychotics

Answer 19

Effective in treatment of
-acute mania
-bipolar depression
-prevent relapse of mania and depression

Question 20

First gen antipsychotics

Answer 20

Chlorpromazine
Loxapine
Fluphenazine
Haloperidol

Question 21

First gen uses

Answer 21

For positive symptoms
minimal impact on negative symtpoms
Many side effects

Question 22

Extrapyramidal symptoms

Answer 22

Pseudoparkinsonism
—stooped posture, shuffling gait, tremors
Acute dystopia
—neck pain, muscle spasms
Akathisia
—feet in constant motion
Tardive dyskinesia
—sucking, smacking, chewing motion

Question 23

Acute dystonia treatment

Answer 23

Benztropine
Diphenhydramine

Question 24

Tardive dyskinesia treatment

Answer 24

Lower dosage
Benztropine

Question 25

Akathisia treatment

Answer 25

Propranolol
Benzodiazepines

Question 26

Pseudoparkinsonism treatment

Answer 26

Benztropine
Trihexyphenidyl

Question 27

Antipsychotics side effects

Answer 27

Sedation
Orthostatic hypotension
Lowered seizure threshold
Increased prolactin
-sexual dysfunction
-galactorrhea
-amenorrhea
-gynecomastia

Question 28

Metabolic syndrome

Answer 28

Weight gain
Hypertension
Diabetes
Dylipidemia

Question 29

Neuroleptic malignant syndrome

Answer 29

Muscle rigidity
High fever
Fluctuating BPs
Irregular and increased HR
Increased RR
Altered mental status (AMS)

Question 30

Second/third antipsychotics

Answer 30

Aripiprazole
Clozapine
Lurasidone
Olanzipine
Quetiapine
Risperidone

less likely to have EPS

Question 31

Clozapine adverse effects

Answer 31

Agranulocytosis (this is always gonna happen they just don’t know when)
-monitor for fever
Myocarditis
Siallorhea (drooling)
used as a last resort medication