Week 5 Flashcards
(24 cards)
What does NSAID mean?
Non-steroid anti-inflammatory drugs
What does Aspirin interact with?
Anti-coagulant - warfarin/heparin Glucocorticoids Alcohol Ibuprofen ACE inhibitors, angiotensin receptor blockers
What are adverse effects for Celecoxib (Celebrex)?
Dyspepsia - upper gut pain Abdominal pain Renal toxicity Sulfonamide allergy Cardiovascular impact - stroke, MI, and other serious events Use in pregnancy
What are the adverse effects of Glucocorticoids?
Adrenal insufficiency Osteoporosis Infection Glucose intolerance Myopathy Electrolyte disturbance Growth retardation Glaucoma and Cataracts Peptic ulcer disease
Treatment for Gout
NASAID- pain/ inflammation
Glucocorticoids-effective alternative if pt has renal disease
Types of cells in nervous system (2)
Neurons and glia
Neuron structure and function
Major division of nervous system
Central nervous system
Peripheral nervous system - somatic/ autonomic
What is the Neurons role?
Process information - sense environmental changes/communicate to other Neurons
What is the glia role?
Insulate, support and nourish Neurons
Parts of the Neuron?
Soma - cell body
Dendrites
Axon
The autonomic nervous system consists of? (2)
Sympathetic and Parasympathetic
(3) types of tissue
Glands
Smooth Muscle
Cardiac Muscle
Autonomic Nervous System - Sympathetic anatomy
Branch from thoracic and lumber spinal nerves
Autonomic Nervous System - Parasympathetic Anatomy
Cranial Nerves - 3, 7, 9, 10
Pelvic Nerves exiting from s2-s4
Function of the Sympathetic route
Mobilise body for short term emergencies
Fight or flight - fright or sex’
Increase heart rate
Glucose mobilisation
Function of the Parasympathetic
Works calmly for long term good
Rest and digest
Facilitates digestion, energy storage, growth, immune response.
Decreases heart rate, increase gut motility (digestion)
What types of tissue does the sympathetic and parasympathetic nervous system innervate?
Cardiac Muscle
Smooth Muscle
Glands
Neurotransmission - types of synapses (2)
Electrical (rare)
Chemical
Sympathetic Neurotransmitters (3)
ACh - acetylcholine
E - (epinephrine) - adrenaline
NE - (norepinephrine) - noradrenaline
Neurotransmission receptors (2) categories
Cholinergic receptors - respond to acetylcholine
Adrenergic receptors- respond to adrenaline and noradrenalin
Receptor sub types (2)
Alpha
Beta
Which neurotransmitter does the parasympathetic nervous system use?
Acetylcholine
What does Cox mean?
Cyclo-oxygenase
What is a Ganglionic?
Connection of 2 nerves
