Week 6 - Core

Question 1

What is the tRNA binding site on ribosomes which accepts the incoming tRNA molecule during translation?

Answer 1

The A (aminoacyl) site

Question 2

What are the 3 compounds of a nucleotide?

Answer 2

A sugar, phosphate, nitrogen-containing side group (base)

Question 3

What are the main features of RNA processing?

Answer 3

5’ cap, 3’ poly-A tail, and removal of introns via splicing

Question 4

A couple have 3 children, aged 12, 8, & 3 weeks. The new born (neonate) child is diagnosed with phenylketonuria (PKU), an autosomal recessive condition. What is the likelihood that each of the other 2 children carry the recessive allele?

Answer 4

2/3, this is because there is a 25% of having 2 normal alleles (non carrier), 50% chance if one normal and one recessive allele (carrier), and 25% chance inheriting 2 recessions (affected)

Question 5

A single layer of tall, skinny epithelial cells would be best described as…

Answer 5

Simple columnar epithelium

Question 6

What TLRs (toll-like receptors) are found on the cell surface?

Answer 6

TLR 1, 2, 4, 5, 6, & 10

Question 7

What bacterium was responsible for the plague?

Answer 7

Yersinia Pestis

Question 8

What micro-organism, now considered eradicated, has been the single agent/disease responsible for most diseases d the estimated infectious disease mortality in the last century?

Answer 8

Smallpox Virus

Question 9

What is the critical initial step of the infectious process?

Answer 9

Exposure

Question 10

What micro-organism is responsible for leprosy?

Answer 10

Mycobacterium Leprae