Week 7 - Cancer

Question 1

tobacco % cancer

Answer 1

30

Question 2

diet , alcohol % cancer

Answer 2

38

Question 3

Cancer three step

Answer 3

Initiation (mutation and cell transformation)

Proliferation (establishment of transformed cell line)

Invasion (integration into the tissues, spread to other organs - metastasis)

Question 4

carcinogenesis =

Answer 4

damage to proto/anti-oncogenes

Question 5

c-Ras

Answer 5

proto-oncogene, protein involved in signal transduction

Question 6

P53 tumour suppressor protein

Answer 6

anti-oncogene

Question 7

What % cancer - inherited genes

Answer 7

thought only 5-10%

Question 8

foods containing dietary fibre - cancer

Answer 8

probably decrease colorectum

suggestive decrease oesophagus

Question 9

aflatoxins - cancer

Answer 9

convincing evidence increase liver

Question 10

non-starchy vegetables - types

Answer 10

leafy: spinach, lettuce
cruciferous: bok choy, broccoli, cabbage, watercress
allium: onions, leeks, garlic

Question 11

garlic - cancer

Answer 11

prob dec colorectum

Question 12

non-starchy veg - cancer

Answer 12

prob dec: oesophagus, stomach, mouth/pharynx/larynx

Question 13

fish - cancer

Answer 13

sugg dec colorectum

Question 14

red meat - cancer

Answer 14

conv inc colorectum

Question 15

milk - cancer

Answer 15

prob dec colorectum

Question 16

fat - cancer

Answer 16

sugg inc lung, breast

animal - colorectum

Question 17

salt - cancer

Answer 17

prob inc stomach

Question 18

physical activity - cancer

Answer 18

conv dec colon
prob dec breast-post, endometrium
sugg - lung, pancreas, breast-pre