Week 8 - HIV, hepatitis, coronavirus, bacteriophages Flashcards
(31 cards)
Every zoonotic coronavirus has originated in bats. True or false?
True.
When was the SARS epidemic?
2002-4
What does MERS stand for?
Middle East Respiratory Syndrome
When was the MERS epidemic?
2012.
Classify SARS-CoV2.
Enveloped ss(+)RNA virus.
SARS-CoV-2 comes from family Coronaviridae. True or false?
True.
What is the ‘N’ protein in a virus? What does it do in coronaviruses?
Nucleoprotein, winds up the RNA genome.
What is the ‘M’ protein, and what does it do in coronaviruses?
Membrane protein, forms the capsid.
SARS-CoV-2 has a 45kb genome. True or false?
False. It is 30kb.
The ‘S’ protein in coronaviruses stands for…
Spike protein.
What receptor on the surface of cells do SARS-Cov-2 spike proteins target?
ACE2 receptor.
Classify the hepatitis C virus.
Enveloped ss(+)RNA.
What cells does hepatitis C target?
Hepatocytes in the liver.
From what family does the hepatitis C virus come from?
Flaviviridae.
The hepatitis C genome is 15kb. True or false?
True.
Treatment that directly acts against RNA polymerase or proteases are called DAAs, or…
Direct acting antivirals.
Which immune cells decline in an HIV patient?
CD4+ memory T cells
Viruses that convert genomic viral RNA into cellular DNA are called:
Retroviruses.
What is the key enzyme of retroviruses?
Reverse transcriptase.
HIV can be suppressed, HCV can be cured. True or false?
True.
What is the most abundant DNA-replicating agent on the planet?
Bacteriophages.
What are three phage structures?
- Filamentous
- Head-tail / T-even
- Icosahedral
A temperate phage uses which cycle?
Lysogenic cycle.
A virulent phage uses which cycle?
Lytic cycle.
