Week 9: Fluids Flashcards

1
Q

body fluid

A

total body water=60%
intracellular 2/3 TBW
extracellular 1/3 TBW (intersititial fluid 3/4 of ECF, intravascular/plasma 1/4 of ECF)

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2
Q

plasma

A

5% of body weight

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3
Q

blood volume

A

8-9%-dogs and large animals

6-7& cats

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4
Q

calculating blood volume

A

dogs and large animals=90 ml/kg lean body weight

cats-60ml/kg lean body weight

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5
Q

electrolytes

A

cations: pos charge

anions=neg charge

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6
Q

colloids

A

large molecular weight

plasma protein

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7
Q

anions

A

chloride CL-
Bicarbonate HCO3-
Phosphates HPOr-
Proteins

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8
Q

cations

A

sodium NA+
Potassium K+
Magnesium MG 2+
Calcum CA2+

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9
Q

homeostasis

A

normal constant state

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10
Q

water solute movement

A

passive and active diffusion

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11
Q

Water permiability

A

across all membranes

concentration gradient

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12
Q

Electrolyte permeability

A

across vascular membrane not cellular

distributes throughout ECF

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13
Q

Colloid Permeability

A

fluid with large molecules

stay within the vasculature

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14
Q

water solute balance

A

pos and neg charge must be equal
solute provide osmotic pressure
small solutes pass freely intravascular space from interstitial space

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15
Q

IV fluids

A

1/3 fluids stay in intravascular space, 2/3 interstitial

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16
Q

Dehydration

A

depletes ECF

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17
Q

perioperative hemorrhage

A

loss of intravascular space

hypertonic saline or colloid

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18
Q

low albumin

A

blood plasma or colloid solution

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19
Q

IV

A

fast/versatile preferred

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20
Q

SQ

A

absorbed 6-8 hrs

isotonic

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21
Q

IO

A

fast alternative to IV

neonates

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22
Q

Crystalloids

A

electrolytes in water
hypotonic
isotonic
hypertonic

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23
Q

hypotonic

A

more water than electrolytes
5% dextrose,
0.45% NaCL, Normosol M, plasmalyte 56

24
Q

isotonic

A

equal osmolaity

0.9% NaCL, Normosol R, Plasmalyte, 148 LRS

25
Hypertonic
electrolytes | 3% and 7% NaCL
26
Colloids
high molecular weight natural=plasma/albumin solution synthetic=hetastarch, vetstartch, dextran 70
27
Surgery fluids
isotonic, polytonic, replacement fluids
28
sick patients
PCF less than 20 TP less than 3.5 g/dL isotonic, polytonic replacement fluids
29
Crystalloids
Isotonic, polytonic, replacement LRS, Normosol R, Plasma Lyte A and R, Isolyte S, , contains dextrose
30
resuscitation phase
restore vascular volume | reverse hypovolemic shock
31
replacement phase
correct dehydration | replace and maintain fluids
32
maintenance phase
after dehydration is corrected hypotonic crystalloids 40-60 ml/kg/day
33
potassium chloroide
hypokalemia
34
dextrose
hypoglycemia
35
sodium bicarbonate
use with caution metabolic acidosis severe hyperkalemia
36
administration anesthesia and surgery
<10 ml/kg/hr during first hr | 3-5 ml/kg/hr during rest of procedure
37
volume overload
``` pulmonary edema cavity effusion peripheral edema hemorrhage compromised patients (especially cats) ``` use slower infusion rate
38
overhydration
``` ocular nasal discharge chemosis subcutaneous edema increased lung sounds increased respiratory rate and dyspnea coughing and restlessness if awake hemodilution ```
39
Fresh whole blood
``` contains: RBC WBC platelets all coagulation factors proteins: albumin and globulin store for up to 8 hrs ```
40
stored whole blood
lose platlets fewer coagulation factors store up to 28 days refrigerated
41
packed red blood cells
whole blood spun down plasma removed: RBC WBC
42
why give pRBC
anemia trauma IMHA cancer
43
plasma
all coagulation factors | protein: albumin, globulin
44
store plasma
liquid-refrigerated 14 days fresh frozen-up to 1 year frozen-up to 5 years (lose coagulation)
45
why give plasma
``` replace coagulation factors and/or proteins: rodenticide toxicity hemophilia DIC/heatstroke Von Wilebrand's Hypoproteinemia ```
46
DEA 1
dog erythrocyte antigen | positive or negative
47
DEA 4
most dogs have this antigen
48
universal donor dogs
DEA 4+= best | DEA 1 negative= universal
49
In house blood type testing
DEA | alveida
50
DMS Card Type
less expensive | results show agglutination
51
who gets what type
DEA -1 can donate to pos or negative DEA 1+ can only donate to positive
52
Feline blood types
``` A=most common B=strong A antibodies AB rare no universal blood donor always type ```
53
crossmatch
if patient has transfusion before if cannot type a cat best practice any transfusion
54
pRBC transfusions | dogs
do not warm gravity vest for dogs: syringe or fluid pump use at least 22 gauge catheter
55
pRBC transfusion cats
syring pump preferable use hemonate filter administer within 4 hrs
56
fresh frozen plasma transfusion
slowly that | warm bath 30-37 degrees