Weeks 1-4 Flashcards
(20 cards)
What is pKa value?
Used to determine the strength of acids. pKa = -log10Ka
What is an acid?
Proton donor, must contain Hydrogen
What is a base?
Proton acceptor, must contain a lone pair of electrons to bind the H+ ion.
What determines if an acid OR base is strong or weak?
If it dissociates completely
What is pKb value
Used to determine the strength of bases. pKb = -log10Kb
What is a buffer
A solution/mixture of a weak acid and its conjugate base
How do you calculate Ka
Ka= [H3O]+x[A-]/[HA]
What differentiates a Alpha 1-4 link and a Beta 1-4 link?
In alpha 1-4 links the OH hydroxyl group on C1 is below the ring plane whereas is beta 1-4 links it is above the ring plane (beta = up, alpha= down as monosachrides)
What is a D configuration monosaccharide?
A monosaccharide with the hydroxyl -OH group on the penultimate carbon facing the right in the fischer projection
What is an L configuration monosaccharide?
A monosaccharide with the hydroxyl -OH group on the penultimate carbon facing the left in the fischer projection
What is the penultimate carbon
The penultimate carbon is the chiral carbon atom farthest from the carbonyl group (aldehyde or ketone) that determines whether a sugar is designated as D or L
What is an anomeric carbon
The new sterocentre resulting from cyclic hemiacetal formation
What is an anomer
Carbohydrates that differ in configuration at their anomeric centers
What are the diverse roles of proteins?
Structure of cells
Replication of cells
Transportation
Catalysis of reactions
Signalling of messages
combating infection
Describe the Primary structure of a protein
A sequence of amino acids
Describe the secondary structure of a protein
a sequence of amino acids folded in on itself
Describe the tertiary structure of a protein
Secondary structure folded in on itself
Describe the Quaternary structure of a protein
2 or more tertiary structures joined together.
Amino acid properties
Capacity to polymerize
useful acid-base properties
Varied physical properties
Varied chemical functions