welz

Question 1

a German surgeon and pathologist who first described welz tumor

Answer 1

Dr. Max Wilms

Question 2

Wilms tumor, also known as

Answer 2

nephroblastoma

Question 3

ETIOLOGICAL CAUSES AND FACTORS

Answer 3

Genetic alterations development of
the genitourinary tract.

family history of Wilms tumor

Having persistent metanephric tissue or
nephrogenic rests

Have a urological disorder

Question 4

two embryological
structures that give rise to the kidney

Answer 4

metanephric
blastema

Question 5

metanephric blastema that grow after 36 weeks of gestational age are called

Answer 5

nephrogenic rests.

Question 6

nephrogenic rests are associated with

Answer 6

nephroblastomatosis

Question 7

a precursor
lesion to Wilms tumors.

Answer 7

nephroblastomatosis

Question 8

Wilms tumor can occur as part of rare
syndromes.

Answer 8

WAGR syndrome

Denys-Drash syndrome

Beckwith-Wiedemann syndrome

Question 9

disorder
that affects many body systems and
is named for its main features

Answer 9

WAGR syndrome

Question 10

WAGR syndrome stands for

Answer 10

Wilms tumor, Aniridia, Genitourinary anomalies, and a Range of developmental delays

Question 11

characterized by kidney disease that
begins within the first few months of
life

Answer 11

Denys-Drash syndrome

Question 12

classified as an
overgrowth syndrome, which means that affected infants are larger than
normal

Answer 12

Beckwith-Wiedemann syndrome

Question 13

PHYSICAL EXAMINATION d is usually identified when a
caregiver notices a

Answer 13

abdominal swelling

Question 14

color of patient

Answer 14

pallor

Question 15

The mass is typically confined to what area

Answer 15

flank area

Question 16

is common due to
increased renin secretion from the
tumor.

Answer 16

Hypertension

Question 17

e present in 20% of cases.

Answer 17

hematuria

Question 18

metastatic signs such as

Answer 18

respiratory distress (lung metastasis) or
hepatomegaly

Question 19

Create image of the kidneys help find whether a child has a kidney tumor

Answer 19

Imaging test

Question 20

test to determine if the
cancer has spread (metastasized):

Answer 20

Abdominal ultrasound

Bone scan

CT scan

Chest X-ray

MRI

Question 21

tissue is removed and
examined under a microscope

Answer 21

Biopsy

Question 22

Uses by healthcare provider
throughout europe
● Uses surgery after chemotherapy to
do the staging

Answer 22

International Society of Paediatric
Oncology (SIOP)

Question 23

● Uses surgery to stage the tumor
before chemotherapy

Answer 23

Children’s Oncology Group (COG)

Question 24

s the name for the way that healthcare
providers determine if and how far the cancer has
spread beyond its original location

Answer 24

Staging

Question 25

Found only in your child’s kidney ● Removed completely after surgery What stage:

Answer 25

Stage I

Question 26

What stage: Tumor has grown past your child’s kidney ● Also remove completely

Answer 26

Stage II

Question 26

What stage: ● Tumor is not able to be remove completely ● Some tissue remains in your child’s abdominal area

Answer 26

Stage III

Question 26

What stage: Tumor has grown beyond your child’s abdomen and pelvis to places like their lungs, liver, bone, or brain

Answer 26

Stage IV

Question 27

What stage: V ● Tumor is bilateral, or present in both kidneys ● Provider will do staging on each kidney separately

Answer 27

Stage V

Question 28

chemo drugs used most often are:

Answer 28

Actinomycin D (dactinomycin) ● Vincristine

Question 29

Short-term side effects can include:

Answer 29

● Hair loss ● Mouth sores ● Loss of appetite ● Nausea and vomiting

Question 30

Drug-specific side effects

Answer 30

Vincristine can damage nerves. Doxorubicin can damage the heart

Question 31

tingling, numbness, weakness, or pain, particularly in the hands and feet

Answer 31

peripheral neuropathy