Wernicke and Korsafoff

Question 1

• Psychosis induced by Vitamin B1, thiamine deficiency
• This is a situation the pt looses touch with reality due to vit B1 deficiency
• The primary S/Sx are amnesia (memory loss) and confabulation (making up stories)
o Confabulation—The lies for this pts are just as real as reality

Answer 1

Wernicke and Korsafoff

Question 2

How do deal with a pt with Wernicke and Korsafoff who is confabulating about going to a meeting with Barack Obama this morning?

Answer 2

Redirect the pt to something he can do
o For instance, tell pt something along that line: “Why can we go watch TV to see what is
on the news today”

Question 3

• it is preventble.. tabe b1
  2. Can stop from getting worse.. take b1
  3. Irreversible (70%)… will kill braincells

Answer 3

Wernicke and Korsafoff syndrome

Question 4

co -enzyme that helps mltelbolyi Wilmot . If low b1 = 0 metabolize , it will build
up in their brain and destroy it

Answer 4

B1

Question 5

It is an alcohol deterrent

Answer 5

Antabuse

Question 6

Antidote
• Aversion (strong hatred) Therapy—a type of behavior therapy designed to make a patient
give up an undesirable habit by causing them to associate it with an unpleasant effect
Boards only o Works in theory better than in reality

Answer 6

Revia

Question 7

It is aversion theraphy

Answer 7

Antabuse and Revia (Disulfiram)