what would you prescribe for...

Question 1

urinary incontinence

Answer 1

anitmuscarinics (bethanachol/ureocholine)

Question 2

MOA antimuscarinics

Answer 2

parasympathetic stimulation causes bladder spasm

Question 3

Contraindications for antimuscarinics

Answer 3

GI obstruction, asthma, parkinsons, PUD

Question 4

ADR antimuscarinics

Answer 4

HOTN, tachy, cramping, diarrhea

Question 5

Acute causes of BPH

Answer 5

antiarrhytmics, antihypertensives, OTC cold meds

Question 6

Chronic cause of BPH

Answer 6

weak detrusor

Question 7

treatment of BPH

Answer 7

alpha blockers, PDE5i, 5 alpha reductase inhibitors

Question 8

Name the alpha blockers

Answer 8

Doxazosin (Cardura), Tamsulosin (Flomax)

Question 9

Name the 5 alpha reductase i

Answer 9

dutasteride (Avodart), finasteride (proscar)

Question 10

name the PDE5i

Answer 10

cialis (tadalafil)

Question 11

which alpha blockers work on all three alpha receptors

Answer 11

doxazosin, terazosin, alfuzosin

Question 12

which alpha blocker works only on BV and would be good in HTN

Answer 12

silozosin

Question 13

What alpha blocker is selective for alpha A and D?

Answer 13

tamsulosin

Question 14

what is something to look out for with prescribing alpha blockers along with other drugs?

Answer 14

interactions!!

Question 15

Do alpha blockers work?

Answer 15

the decrease LUTS, no long term benefit

Question 16

MOA of 5 alpha reductase i

Answer 16

decrease DHT levels

Question 17

benefits of finasteride/dutasteride?

Answer 17

finasteride has a faster onset and dutasteride has a longer half life

Question 18

how is the PSA affected with 5 alpha reductase i?

Answer 18

after 6 months of therapy the new PSA baseline is cut 50%

Question 19

ADR of dutasteride and finasteride?

Answer 19

impotence, high TSH, decreased libido

Question 20

Treatment for erectile dyfunction

Answer 20

PDE5i, yohimbine, enzyte, vasotran auctum

Question 21

name the PDE5i

Answer 21

tadalafil (cialis), sildenafil (Viagra)

Question 22

MOA of PDE5i

Answer 22

increase cGMP

Question 23

ADR of sildenafil

Answer 23

PDE6 attack causes blue vision

Question 24

ADR of tadalafil

Answer 24

PDE11 attack causes back pain

Question 25

ADR of PDE5i in general

Answer 25

photosensitivity, HA, flushing

Question 26

alternative treatment use of PDE5i

Answer 26

PAH

Question 27

contraindications for PDE5i

Answer 27

nitrate use, also using alpha blockers (add PDE5i on when alpha blockers are stable)

Question 28

erection lasting more than 4 hours should get

Answer 28

ephedrine, NE, aspiration

Question 29

MOA of yohimbine

Answer 29

alpha 2 blocker

Question 30

ADR yohimbine

Answer 30

HTN, nervousness, tremor

Question 31

MOA of vasotran auctim

Answer 31

produced NO

Question 32

components of vasotram auctum

Answer 32

lL-arginine, yohimbine, ginseng, methyl nicotinate

Question 33

components of enzyte

Answer 33

ginkgo, saw palmetto, ginseng, yohimbine, mala, tribulus terrestris

Question 34

treatment of female sexual dysfxn

Answer 34

local estrogens, testosterone creams, sildenafil

Question 35

treatment of dyspareunia

Answer 35

ospemifene (estrogen receptor modulator)

Question 36

ADr ospemifine

Answer 36

flushing